The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
1134
3D
2rc4A02 - 88.4
2
1043
3D
2ou2A02 - 87.9
3
800 - - 83.2
4
604
3D
4nsqD00 - 80.7
7
1
438
3D
4r9mC00 - 69.3
5
376 - - 95.4
6
348 - - 95.5
8
291 - - 39.0
9
256 - - 63.4
10
253 - - 80.2
11
253
3D
3bj8D00 - 94.7
12
210 - - 38.0
13
208 - - 86.6
14
205
3D
6c9mD00 - 65.9
15
201 - - 76.5
18
195
3D
2cntD00 - 78.9
16
192 - - 95.0
17
191 - - 77.8
19
181 - - 65.7
26
179
3D
3dr8B00 - 93.8
20
178
3D
4h6zB02 - 78.7
21
175
3D
1l0cA00 - 79.9
22
165
3D
2p0wB02 - 77.3
25
156
3D
2vqyA00 - 43.7
23
153 - - 78.4
24
149 - - 52.5
29
147
3D
4ab7H02 - 98.0
28
141
3D
5icwB00 - 68.5
27
140 - - 8.4
31
129
3D
3cxsA01 - 74.7
30
123 - - 80.7
42
116
3D
2p6gF01 - 78.7
32
115 - - 26.7
33
113 - - 86.4
34
112 - - 77.3
35
110
3D
1xebH00 - 85.8
56
100
3D
2p6gF02 - 89.3
36
96 - - 11.1
46
89
3D
3v8iB00 - 97.1
38
87
3D
5ls7B00 - 10.1
37
85 - - 76.8
43
78
3D
4ag9B01 - 92.9
39
78 - - 80.3
40
putative
77 - - 78.9
44
76
3D
2ft0B00 - 53.0
41
76 - - 84.1
45
74
3D
4k30Y00 - 78.4
52
69
3D
1z9uB00 - 33.9
47
69
3D
3tcvB00 - 94.0
48
68
3D
3t90A00 - 93.3
49
65 - - 85.3
50
64 - - 8.9
60
64
3D
4u9zA00 - 86.4
51
63 - - 75.7
54
Met
61
3D
2zpaB03 - 69.3
55
61
3D
1y9wB01 - 77.1
53
60 - - 73.4
62
60
3D
3fxtH00 - 92.3
57
57 - - 42.5
58
Nat5
55 - - 74.4
59
54 - - 78.0
66
53
3D
1qsoD00 - 89.8
61
N
alpha
53 - - 70.2
64
51
3D
2fe7B00 - 93.7
63
50 - - 57.6
112
49
3D
6b3tA01 - 94.7
65
48 - - 89.0
71
43
3D
4f0yB00 - 80.6
68
43 - - 23.4
67
43 - - 81.6
70
42
3D
3s6kA02 - 80.5
69
41 - - 13.9
78
38
3D
2pswC00 - 16.9
72
35 - - 92.7
73
34 - - 74.4
74
N
alpha
34 - - 24.0
75
33 - - 73.4
76
33 - - 89.9
77
32 - - 89.0
79
31 - - 38.4
81
31 - - 36.2
80
31 - - 70.7
82
31 - - 67.5
98
30
3D
4kvoH00 - 53.0
89
29
3D
2c27A00 - 45.8
136
29
3D
1i21Y00 - 82.8
83
NAT
29 - - 68.0
84
28 - - 65.9
85
27 - - 62.4
87
27 - - 5.2
86
27 - - 84.0
88
26 - - 71.7
90
26 - - 24.6
106
26
3D
2q4yA00 - 97.1
107
25
3D
4xpdB00 - 52.1
91
25 - - 86.3
93
24 - - 29.4
92
24 - - 59.4
94
24 - - 74.0
105
24
3D
3i3gB00 - 93.8
96
23 - - 18.4
95
23 - - 79.8
114
22
3D
4psxD02 - 86.4
97
22 - - 75.1
99
21 - - 73.7
100
21 - - 95.0
148
20
3D
1yk3H00 - 0.0
111
6'
20
3D
1s3zB00 - 1.5
149
AAC(2'
20
3D
1m4iB00 - 9.1
102
20 - - 6.3
101
20 - - 57.3
104
20 - - 80.2
103
20 - - 38.7
109
19 - - 10.8
110
19 - - 17.4
176
19
3D
2vzzD00 - 0.0
108
19 - - 76.7
115
18 - - 10.7
133
18
3D
1mk4B00 - 93.6
116
18 - - 75.8
113
18 - - 65.9
121
17 - - 9.2
124
17 - - 72.0
123
17 - - 2.4
120
N
alpha
17 - - 0.0
119
17 - - 17.2
122
GNAT
17 - - 1.4
118
17 - - 72.7
183
17
3D
5ib0G00 - 0.0
117
17 - - 71.0
126
16 - - 8.2
132
16 - - 78.7
128
16 - - 88.8
127
16 - - 12.0
131
16 - - 5.0
130
16 - - 14.2
125
16 - - 71.6
129
16 - - 2.6
134
15 - - 2.4
135
15 - - 37.3
200
15
3D
5c88B00 - 83.5
194
15
3D
4avcB02 - 31.2
137
14 - - 0.0
140
Met
14 - - 83.1
138
14 - - 54.2
203
14
3D
4y49O00 - 0.7
139
14 - - 54.6
144
13 - - 5.7
141
13 - - 56.1
143
13 - - 12.7
142
13 - - 79.4
171
13
3D
2h5mA00 - 10.0
155
12 - - 0.8
146
12 - - 42.7
215
12
3D
4x5kA00 - 26.6
147
12 - - 2.4
154
12 - - 0.0
145
12 - - 16.7
151
12 - - 0.7
158
12 - - 98.1
150
12 - - 25.5
153
12 - - 0.0
156
12 - - 68.7
157
12 - - 11.7
152
12 - - 4.6
167
11 - - 80.1
162
11 - - 45.9
159
11 - - 74.1
164
11 - - 39.3
175
11 - - 6.8
161
11 - - 33.1
179
11 - - 36.9
168
11 - - 84.7
163
11 - - 45.6
160
11 - - 0.0
166
11 - - 77.3
181
11 - - 92.3
177
11 - - 6.9
180
11 - - 78.8
172
11 - - 8.3
165
11 - - 53.4
174
11 - - 10.2
170
11 - - 8.1
173
11 - - 0.0
169
11 - - 9.7
178
11 - - 0.0
185
10 - - 3.3
189
10 - - 0.0
184
10 - - 11.0
192
10 - - 93.5
186
10 - - 14.2
188
10 - - 0.0
190
10 - - 0.0
187
10 - - 0.7
191
10 - - 98.7
182
10 - - 82.6
199
9 - - 82.9
209
9 - - 77.4
205
9 - - 0.7
195
9 - - 33.8
202
9 - - 14.0
210
9 - - 41.5
197
9 - - 1.9
207
9 - - 0.8
193
9 - - 42.3
208
9 - - 27.2
196
9 - - 19.9
206
9 - - 4.3
198
NAT
9 - - 41.3
204
9 - - 7.5
201
9 - - 7.5
219
8 - - 7.4
223
8 - - 16.7
220
8 - - 0.0
224
8 - - 0.0
221
8 - - 0.0
222
8 - - 5.0
216
8 - - 73.1
213
8 - - 0.0
218
8 - - 0.0
211
8 - - 74.9
225
8 - - 45.2
214
8 - - 67.9
212
8 - - 13.3
217
8 - - 13.2
246
7 - - 18.9
243
7 - - 3.9
228
7 - - 5.6
232
7 - - 44.6
240
7 - - 0.0
248
7 - - 82.5
226
7 - - 43.4
241
7 - - 3.1
237
7 - - 18.2
244
7 - - 12.4
238
7 - - 10.0
230
Met
7 - - 0.0
242
7 - - 1.5
233
7 - - 34.1
236
7 - - 13.0
234
7 - - 84.5
247
7 - - 2.6
227
7 - - 4.1
231
7 - - 48.6
229
7 - - 2.2
245
7 - - 6.5
239
7 - - 11.2
235
7 - - 0.0
259
6 - - 14.1
262
6 - - 0.0
267
6 - - 0.0
255
6 - - 24.4
263
6 - - 0.0
260
6 - - 0.0
266
6 - - 0.7
621
6
3D
2g0bH01 - 0.0
279
6 - - 30.5
268
6 - - 0.0
275
6 - - 9.3
261
6 - - 14.9
264
6 - - 14.4
250
6 - - 7.4
249
6 - - 20.6
253
6 - - 16.5
272
6 - - 3.2
256
6 - - 87.4
280
6 - - 85.8
258
6 - - 3.9
251
6 - - 6.8
281
NAT
6 - - 78.2
277
6 - - 0.0
254
6 - - 0.0
282
6 - - 94.3
269
6 - - 8.0
278
6 - - 83.7
270
6 - - 8.3
273
6 - - 2.9
252
6 - - 23.5
276
6 - - 0.0
257
6 - - 61.7
274
6 - - 1.6
265
6 - - 0.0
271
6 - - 0.0
289
5 - - 83.1
285
5 - - 33.2
295
5 - - 8.9
305
N
alpha
5 - - 77.8
379
1
5
3D
3k9uB00 - 0.0
299
5 - - 7.8
288
5 - - 74.0
286
5 - - 42.4
297
5 - - 4.0
283
5 - - 78.4
284
5 - - 23.2
302
5 - - 36.1
292
5 - - 10.4
304
5 - - 63.9
294
5 - - 7.6
301
5 - - 0.0
291
5 - - 16.5
298
5 - - 5.1
293
5 - - 1.2
306
5 - - 84.2
290
5 - - 52.4
303
5 - - 36.4
300
5 - - 0.0
287
N
alpha
5 - - 42.6
296
5 - - 0.0
341
4 - - 9.0
324
4 - - 10.4
337
4 - - 0.0
344
4 - - 78.1
321
4 - - 0.0
315
4 - - 69.6
346
N
alpha
4 - - 45.0
319
4 - - 9.8
328
4 - - 12.7
332
4 - - 1.8
343
4 - - 69.0
340
NAT
4 - - 7.9
348
4 - - 84.4
323
4 - - 14.6
320
4 - - 5.5
326
4 - - 12.6
334
4 - - 3.3
347
4 - - 57.4
327
4 - - 0.0
331
4 - - 8.2
338
4 - - 9.6
322
4 - - 0.0
330
4 - - 0.0
333
4 - - 18.5
309
4 - - 0.0
342
4 - - 0.0
336
4 - - 0.0
447
4
3D
2wpxB00 - 0.0
311
4 - - 18.5
325
4 - - 15.1
314
4 - - 17.1
307
4 - - 74.8
345
4 - - 11.0
316
4 - - 16.3
349
4 - - 18.7
313
4 - - 24.1
310
4 - - 77.7
318
4 - - 0.0
329
4 - - 4.4
335
4 - - 6.0
317
4 - - 0.0
308
4 - - 16.6
312
Arylalkylamine N-AcetylTransferase
4 - - 18.0
339
4 - - 0.0
367
3 - - 5.3
385
3 - - 0.0
355
3 - - 0.0
359
3 - - 16.1
362
3 - - 4.4
375
3 - - 9.0
361
3 - - 6.7
364
3 - - 5.9
363
3 - - 0.0
360
3 - - 69.2
366
3 - - 0.0
368
3 - - 5.7
384
3 - - 0.0
351
3 - - 13.3
377
3 - - 1.5
381
3 - - 0.0
354
3 - - 0.0
350
3 - - 71.2
388
3 - - 57.3
353
3 - - 0.0
356
3 - - 16.8
372
3 - - 0.0
445
3
3D
2z0zA00 - 0.0
386
3 - - 12.2
383
3 - - 5.8
358
3 - - 41.7
380
3 - - 9.1
357
3 - - 1.6
374
3 - - 7.2
365
3 - - 14.1
371
NAT
3 - - 7.8
387
3 - - 35.1
382
3 - - 15.9
378
3 - - 0.0
369
3 - - 6.9
370
3 - - 0.6
373
3 - - 9.3
376
3 - - 9.2
352
3 - - 59.9
423
2 - - 37.8
448
2 - - 0.0
420
2 - - 31.6
489
2 - - 0.0
462
2 - - 0.0
426
2 - - 0.0
419
2 - - 31.0
446
2 - - 5.6
459
2 - - 0.0
443
2 - - 0.0
428
2 - - 0.0
432
2 - - 0.0
440
2 - - 0.0
455
2 - - 0.0
437
2 - - 0.0
444
2 - - 0.0
421
2 - - 31.7
415
2 - - 38.2
515
2 - - 43.9
441
2 - - 0.0
389
2 - - 33.9
467
2 - - 4.2
485
2 - - 11.4
424
2 - - 40.7
430
2 - - 3.4
409
2 - - 0.0
442
2 - - 0.0
433
2 - - 0.0
436
NAT
2 - - 0.0
479
2 - - 11.7
468
NAT
2 - - 7.6
463
2 - - 0.0
495
6
2 - - 0.0
460
2 - - 0.0
509
2 - - 35.7
438
2 - - 11.7
422
2 - - 39.1
466
2 - - 8.8
399
2 - - 7.5
505
2 - - 0.0
427
2 - - 0.0
395
2 - - 9.4
499
AFU_orthologue AFUA_3G11780
2 - - 0.0
431
2 - - 0.0
464
2 - - 0.0
475
2 - - 5.5
434
2 - - 5.2
461
2 - - 0.0
405
2 - - 0.0
418
2 - - 21.3
510
2 - - 36.2
513
2 - - 41.4
486
2 - - 0.0
497
2 - - 11.0
516
2 - - 41.2
483
2 - - 1.9
502
2 - - 0.0
429
2 - - 8.9
480
2 - - 1.4
392
2 - - 13.8
458
2 - - 10.3
488
2 - - 0.0
450
2 - - 0.9
402
2 - - 2.5
453
2 - - 0.0
449
2 - - 0.0
416
2 - - 19.8
472
2 - - 0.0
456
2 - - 8.8
413
2 - - 0.0
410
2 - - 8.7
481
2 - - 9.3
477
2 - - 0.0
414
2 - - 0.0
454
2 - - 0.0
407
2 - - 0.0
511
2 - - 44.2
411
2 - - 0.0
507
2 - - 0.0
425
2 - - 6.7
397
2 - - 0.0
484
2 - - 0.0
514
2 - - 42.0
492
2 - - 0.0
451
2 - - 0.0
470
2 - - 9.7
473
2 - - 7.0
406
2 - - 11.8
412
2 - - 2.8
403
2 - - 0.0
452
2 - - 0.0
398
2 - - 3.0
491
6'
2 - - 0.0
476
2 - - 8.2
439
2 - - 13.3
508
2 - - 26.9
400
2 - - 4.4
500
2 - - 0.0
393
2 - - 24.7
408
O-GlcNAcase
2 - - 1.0
390
2 - - 0.0
482
2 - - 0.0
503
2 - - 0.0
512
2 - - 36.1
506
Met
2 - - 0.0
396
2 - - 11.7
469
2 - - 0.0
494
2 - - 9.9
478
2 - - 0.0
493
2 - - 0.0
401
2 - - 9.9
465
2 - - 0.0
490
2 - - 0.0
504
2 - - 0.0
487
2 - - 0.0
394
2 - - 2.5
471
2 - - 0.0
496
6
2 - - 0.0
457
2 - - 0.0
435
2 - - 0.0
404
2 - - 4.6
391
2 - - 65.7
474
2 - - 0.0
498
2 - - 4.8
501
2 - - 8.2
417
2 - - 24.1
647
1 - - 0.0
540
1 - - 0.0
605
1 - - 0.0
661
1 - - 0.0
528
1 - - 0.0
532
1 - - 0.0
543
1 - - 0.0
634
1 - - 0.0
559
1 - - 0.0
546
1 - - 0.0
519
1 - - 0.0
675
1 - - 0.0
664
1 - - 0.0
526
1 - - 0.0
631
1 - - 0.0
562
1 - - 0.0
699
1 - - 0.0
589
1 - - 0.0
520
1 - - 0.0
627
1 - - 0.0
548
1 - - 0.0
523
1 - - 0.0
524
1 - - 0.0
585
1 - - 0.0
666
1 - - 0.0
622
1 - - 0.0
638
1 - - 0.0
660
1 - - 0.0
567
GNAT
1 - - 0.0
695
1 - - 0.0
541
1 - - 0.0
663
1 - - 0.0
521
1 - - 0.0
668
1 - - 0.0
679
1 - - 0.0
636
1 - - 0.0
633
1 - - 0.0
544
1 - - 0.0
609
1 - - 0.0
642
1 - - 0.0
630
1 - - 0.0
537
1 - - 0.0
555
GNAT
1 - - 0.0
624
1 - - 0.0
566
1 - - 0.0
685
1 - - 0.0
538
1 - - 0.0
522
1 - - 0.0
560
1 - - 0.0
667
1 - - 0.0
595
1 - - 0.0
641
1 - - 0.0
563
1 - - 0.0
615
1 - - 0.0
568
1 - - 0.0
536
1 - - 0.0
579
1 - - 0.0
644
1 - - 0.0
533
1 - - 0.0
542
1 - - 0.0
530
1 - - 0.0
655
1 - - 0.0
637
1 - - 0.0
547
1 - - 0.0
640
1 - - 0.0
561
1 - - 0.0
632
1 - - 0.0
628
1 - - 0.0
659
1 - - 0.0
534
1 - - 0.0
643
1 - - 0.0
646
1 - - 0.0
619
1 - - 0.0
575
1 - - 0.0
564
1 - - 0.0
626
1 - - 0.0
531
1 - - 0.0
599
1 - - 0.0
662
1 - - 0.0
620
1 - - 0.0
689
1 - - 0.0
527
1 - - 0.0
648
1 - - 0.0
623
1 - - 0.0
617
1 - - 0.0
698
1 - - 0.0
674
1 - - 0.0
556
1 - - 0.0
572
1 - - 0.0
604
1 - - 0.0
549
1 - - 0.0
553
1 - - 0.0
550
1 - - 0.0
657
1 - - 0.0
635
1 - - 0.0
588
1 - - 0.0
696
1 - - 0.0
558
1 - - 0.0
671
1 - - 0.0
580
1 - - 0.0
529
1 - - 0.0
687
1 - - 0.0
583
1 - - 0.0
597
1 - - 0.0
690
1 - - 0.0
586
1 - - 0.0
665
1 - - 0.0
601
1 - - 0.0
518
1 - - 0.0
693
1 - - 0.0
678
1 - - 0.0
551
1 - - 0.0
694
1 - - 0.0
592
1 - - 0.0
669
1 - - 0.0
682
1 - - 0.0
584
1 - - 0.0
525
1 - - 0.0
608
1 - - 0.0
600
1 - - 0.0
545
1 - - 0.0
554
1 - - 0.0
639
1 - - 0.0
676
1 - - 0.0
691
1 - - 0.0
652
1 - - 0.0
603
1 - - 0.0
612
1 - - 0.0
606
1 - - 0.0
673
1 - - 0.0
577
1 - - 0.0
670
1 - - 0.0
581
NAT
1 - - 0.0
651
1 - - 0.0
578
1 - - 0.0
594
1 - - 0.0
569
1 - - 0.0
692
1 - - 0.0
582
1 - - 0.0
684
1 - - 0.0
625
1 - - 0.0
611
1 - - 0.0
607
1 - - 0.0
645
1 - - 0.0
576
1 - - 0.0
539
1 - - 0.0
654
1 - - 0.0
591
1 - - 0.0
552
1 - - 0.0
573
1 - - 0.0
614
1 - - 0.0
677
1 - - 0.0
570
1 - - 0.0
681
1 - - 0.0
517
1 - - 0.0
610
1 - - 0.0
613
1 - - 0.0
598
1 - - 0.0
656
1 - - 0.0
574
1 - - 0.0
672
1 - - 0.0
616
1 - - 0.0
653
1 - - 0.0
602
1 - - 0.0
649
1 - - 0.0
650
1 - - 0.0
535
1 - - 0.0
557
1 - - 0.0
688
1 - - 0.0
596
1 - - 0.0
571
1 - - 0.0
658
1 - - 0.0
629
1 - - 0.0
680
1 - - 0.0
587
1 - - 0.0
683
NAT
1 - - 0.0
697
1 - - 0.0
590
1 - - 0.0
565
1 - - 0.0
686
NAT
1 - - 0.0
593
1 - - 0.0
618
1 - - 0.0
CATH-Gene3D is a Global Biodata Core Resource Learn more...