The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
2664
3D
3qijB03 - 95.1
2
1890
3D
6d2kA03 - 99.2
3
1459
3D
1ni2B03 - 88.8
4
997
3D
4c0aF03 - 80.3
5
A4
987 - - 68.0
6
969 - - 82.3
7
950
3D
1wi1A01 - 81.2
8
927 - - 92.4
9
907
3D
2r0dB03 - 75.2
10
813 - - 72.2
11
807 - - 79.8
12
801
3D
5c79B00 - 87.9
13
761 - - 91.8
14
Drosophila
736
3D
2p8vA00 - 90.7
15
730
3D
4mt7A02 - 79.4
17
725
3D
4khaA02 - 98.3
16
724 - - 82.5
18
717
3D
5clqD00 - 96.1
19
A4 Fe65
667
3D
3d8fD00 - 71.9
20
648
3D
2cofA00 - 92.6
21
644
3D
5efxA00 - 87.7
22
633 - - 74.6
23
629 - - 77.2
24
623
3D
1mphA00 - 96.0
27
615
3D
6hhjA01 - 92.2
28
612
3D
2mwnB00 - 93.0
25
603 - - 92.6
26
598
3D
4nswB02 - 80.8
31
585
3D
2nmbA00 - 69.2
30
583
3D
5u78D00 - 82.0
29
581
3D
5u1mA00 - 80.7
32
571 - - 79.8
33
561
3D
2rovA00 - 69.2
35
561
3D
1p3rC00 - 75.1
34
557
3D
2yt1A01 - 82.6
36
540
3D
4xwxA00 - 82.2
38
539
3D
1zvrA01 - 91.5
37
531 - - 86.9
47
524
3D
1evhA00 - 86.7
39
521
3D
3hqcA00 - 78.3
40
510
3D
2nz8B02 - 69.5
44
503
3D
1x11B00 - 70.0
42
499 - - 84.8
41
499 - - 88.5
43
496 - - 76.5
45
492
3D
2m38A00 - 40.2
46
491
3D
4gzuB03 - 87.5
48
RalGDS/AF-6
490
3D
4kvgD02 - 84.0
49
468
3D
1eazA00 - 85.6
50
455
3D
2vrwB02 - 84.8
51
446
3D
4wsfA00 - 75.9
52
442
3D
3syxA00 - 88.6
53
434
3D
3a98D02 - 73.2
55
434
3D
5fi1A02 - 72.3
58
429
3D
4ny0D03 - 75.3
54
428 - - 80.8
56
419
3D
2coaA01 - 86.8
57
Drosophila
418
3D
4bbkA00 - 77.2
59
414
3D
1mi1B01 - 79.6
60
406 - - 74.2
61
403 - - 93.2
62
400
3D
3hk0B02 - 89.6
65
396
3D
4k2pD01 - 82.0
63
391 - - 80.8
64
390
3D
1tqzA01 - 84.3
72
387
3D
5jhhE02 - 87.4
67
384
3D
5c5bD02 - 82.0
70
378
3D
3pg7B02 - 53.7
68
Drosophila
377
3D
1pmsA00 - 70.3
66
376 - - 92.4
69
376
3D
5hziB03 - 69.1
71
371
3D
1qc6B00 - 53.5
73
367
3D
2d9vA01 - 97.3
78
361
3D
1rj2J02 - 86.7
75
358
3D
3pvlA04 - 81.2
76
357 - - 80.1
74
357 - - 74.5
77
354 - - 78.5
84
347
3D
6c2yA05 - 85.1
80
341 - - 93.2
79
341 - - 72.9
81
338 - - 95.3
83
334
3D
2dkpA01 - 86.1
82
333 - - 63.6
85
322
3D
3rcpA00 - 92.2
86
315 - - 85.7
87
313
3D
4gzuB02 - 78.6
88
312
3D
1maiA00 - 98.0
89
306 - - 70.5
91
302 - - 72.0
90
302 - - 63.8
92
294 - - 69.8
93
294
3D
1v5uA00 - 68.7
94
280
3D
1v61A00 - 76.8
95
278 - - 53.0
98
274
3D
4ifsA02 - 92.4
96
273 - - 79.7
101
268
3D
2j59R00 - 68.2
97
268
3D
4b6hB00 - 79.5
99
265 - - 95.4
100
262 - - 87.2
102
261 - - 79.9
104
261
3D
5jjdA00 - 84.0
103
260
3D
1uprA00 - 82.3
105
256 - - 73.2
106
255 - - 74.2
107
253 - - 75.7
108
252 - - 77.0
111
251
3D
2y7bA00 - 92.5
110
250 - - 82.4
109
250 - - 86.1
115
249
3D
5xv8B00 - 85.4
112
246 - - 75.0
113
243 - - 74.4
114
243 - - 75.8
116
240 - - 69.6
117
238 - - 66.6
118
237 - - 79.7
121
237
3D
1foeG02 - 79.7
119
236 - - 97.4
120
236
3D
1v89A00 - 80.9
123
231
3D
4wj7D00 - 65.8
122
227 - - 76.5
126
224
3D
2vkiA00 - 75.1
124
221 - - 82.7
125
220 - - 80.2
128
217
3D
2codA01 - 79.3
129
217
3D
1qqgB01 - 68.3
127
216 - - 90.9
130
213 - - 96.7
131
ZWICHEL
212 - - 51.1
132
211 - - 81.1
135
210
3D
2yf0A01 - 93.5
133
210 - - 81.0
134
209 - - 56.2
136
206 - - 93.0
137
205
3D
3so6A00 - 66.1
138
201 - - 80.2
140
199 - - 58.2
139
199 - - 52.6
142
197
3D
4ekuA03 - 78.7
141
197 - - 78.2
143
196 - - 85.3
145
193
3D
4tknC03 - 89.9
144
190 - - 66.0
148
189
3D
3hw2B00 - 93.4
147
188 - - 79.1
146
188 - - 77.4
149
183 - - 95.5
150
181 - - 82.6
152
179
3D
2dtcB00 - 50.7
151
178
3D
2z0qA02 - 76.5
153
177
3D
2dyqA00 - 79.7
154
176
3D
2d9xA01 - 83.5
155
175 - - 89.4
158
174
3D
3mpxA02 - 68.3
156
174 - - 54.1
157
174 - - 81.3
160
172 - - 69.8
159
172 - - 71.7
161
171 - - 72.2
163
170
3D
3tfmA01 - 42.8
162
169 - - 43.7
165
166 - - 79.4
164
166 - - 95.5
167
165 - - 69.8
166
165 - - 60.1
168
164 - - 75.3
169
163 - - 51.4
170
162 - - 85.7
171
162 - - 88.0
172
160 - - 75.4
173
157 - - 58.7
174
153 - - 62.3
175
150
3D
2dn6A00 - 73.0
191
149
3D
2z0pD00 - 74.1
178
149
3D
2elaB00 - 58.4
176
148 - - 82.3
180
146
3D
1zc4D00 - 82.7
177
146 - - 84.9
182
145
3D
2p0hA00 - 85.3
179
143
3D
2ec1A00 - 78.2
181
142 - - 60.3
194
142
3D
2otxB02 - 70.8
184
GEF
141
3D
2rgnE02 - 61.7
183
140 - - 73.0
187
139
3D
1v5mA00 - 73.3
185
139 - - 86.1
186
138 - - 72.5
189
135 - - 73.4
196
135
3D
3au5B04 - 42.3
192
135 - - 46.0
188
135 - - 65.4
190
135 - - 24.5
193
134 - - 60.0
195
133 - - 36.9
197
131 - - 76.7
198
129 - - 31.2
199
127 - - 66.9
200
GEF
126 - - 58.8
202
125 - - 71.1
201
125 - - 60.5
206
124
3D
3pp2B00 - 77.4
203
124 - - 85.6
204
123 - - 83.1
205
GEF
122 - - 70.9
209
122
3D
1wgqA00 - 67.6
208
122
3D
1x1gA00 - 62.2
207
121 - - 64.7
210
121
3D
2lulA00 - 79.9
211
120 - - 70.2
212
120 - - 81.4
213
120
3D
2d9wA01 - 81.4
214
119 - - 93.6
215
117 - - 85.8
217
113 - - 88.7
216
113 - - 64.0
226
111
3D
2i5fA00 - 60.5
218
108 - - 76.5
227
108
3D
4hdqA03 - 46.0
219
106 - - 79.7
220
106
3D
1zyiA00 - 69.8
221
105 - - 34.4
222
105 - - 85.5
223
105
3D
1plsA00 - 75.1
229
104
3D
1fb8A00 - 84.5
224
104 - - 35.7
225
103 - - 25.1
228
102 - - 80.3
246
101
3D
2v76D00 - 71.6
230
Boi2
100 - - 86.4
231
100 - - 90.1
235
98
3D
2oqbB00 - 61.5
236
97
3D
3tfmA02 - 31.2
232
97 - - 48.0
234
PH
96 - - 72.9
233
96 - - 59.5
241
96
3D
2hthB00 - 85.1
237
95 - - 46.2
238
95 - - 63.5
240
94 - - 59.5
239
94 - - 32.0
242
94 - - 85.2
243
94 - - 92.0
244
93 - - 75.1
248
93
3D
2dhkA01 - 93.6
249
92 - - 53.6
247
92 - - 70.2
245
92 - - 71.9
250
91 - - 73.3
252
Csx2
90 - - 91.7
251
90 - - 82.7
253
89 - - 45.4
254
88 - - 66.4
255
87 - - 44.9
256
87 - - 71.7
257
85 - - 52.8
261
85
3D
2cy5A00 - 90.7
258
85 - - 8.9
259
84 - - 72.0
260
83 - - 71.8
262
82 - - 76.3
264
81 - - 96.9
265
81 - - 52.5
263
81 - - 89.9
267
79 - - 85.4
266
79 - - 35.5
268
79 - - 67.4
269
78 - - 99.2
275
77
3D
3ml4D02 - 46.1
272
76 - - 14.6
271
76 - - 66.5
270
76 - - 73.8
277
76
3D
1u5dD00 - 54.6
273
75 - - 24.9
274
74 - - 76.9
276
73 - - 39.4
278
70 - - 71.8
279
70 - - 15.6
281
68 - - 94.9
280
68 - - 53.6
282
68 - - 40.4
285
67 - - 30.9
284
67 - - 44.1
283
67 - - 87.2
286
67 - - 98.2
287
66 - - 63.8
288
65 - - 31.0
289
65 - - 90.0
290
64 - - 63.0
293
64 - - 92.9
292
64 - - 82.8
291
64 - - 62.8
294
63 - - 58.4
295
62 - - 63.7
296
62 - - 37.1
297
61 - - 92.1
298
61 - - 81.7
328
60
3D
4a6kD00 - 93.2
299
59 - - 73.7
301
56 - - 61.7
303
56 - - 95.2
300
56 - - 87.6
302
56 - - 44.4
304
56 - - 87.2
305
55 - - 78.6
307
54 - - 77.9
310
54
3D
4khbH01 - 73.9
306
54 - - 52.0
308
53 - - 87.2
309
52 - - 44.4
311
Bud4
49 - - 76.9
315
49 - - 36.2
317
49 - - 78.8
313
49 - - 77.4
312
49 - - 93.0
316
49 - - 43.2
314
49 - - 48.1
318
48 - - 24.0
319
47 - - 23.5
320
46 - - 49.4
331
46
3D
4emoD00 - 77.4
323
45 - - 19.2
324
45 - - 89.5
322
45 - - 48.4
321
45 - - 76.0
325
44 - - 41.4
326
44 - - 59.5
336
44
3D
3ml4D01 - 46.8
327
44 - - 25.4
330
tre-2/USP6, BUB2, cdc16
43 - - 36.3
329
43 - - 74.3
332
42 - - 61.1
333
41 - - 20.4
335
40 - - 50.6
341
40
3D
5a3fC03 - 40.1
334
40 - - 19.5
337
39 - - 19.3
340
38 - - 38.5
338
38 - - 73.9
342
38 - - 61.0
483
38
3D
6citB00 - 44.4
343
38 - - 64.7
339
38 - - 45.5
344
37 - - 23.9
345
36 - - 17.6
347
35 - - 35.5
348
35 - - 82.7
346
35 - - 52.6
350
34 - - 98.5
349
34 - - 82.9
351
34 - - 82.7
353
33 - - 70.8
352
33 - - 17.4
354
33 - - 66.7
355
33 - - 45.6
356
33 - - 92.9
359
32 - - 31.9
360
32 - - 60.3
361
32 - - 35.3
357
32 - - 61.7
358
ISP1
32 - - 17.6
363
30 - - 65.7
365
30 - - 83.4
364
30 - - 76.9
362
30 - - 93.9
366
29 - - 79.3
367
29 - - 45.1
370
29 - - 58.3
369
29 - - 72.7
368
29 - - 32.8
371
29 - - 16.1
373
28 - - 28.8
372
28 - - 79.4
375
27 - - 70.9
377
27 - - 89.0
374
27 - - 44.7
376
27 - - 93.8
378
26 - - 78.3
389
26
3D
2cocA01 - 41.4
381
26 - - 63.4
382
26 - - 81.5
379
26 - - 16.8
380
26 - - 27.1
391
25 - - 91.8
387
25 - - 62.9
385
25 - - 49.5
484
25
3D
5urnA00 - 34.4
383
25 - - 54.6
390
25 - - 80.7
388
25 - - 63.1
392
25
3D
1x1fA00 - 33.3
386
25 - - 27.9
384
25 - - 92.7
393
24 - - 41.3
395
24 - - 58.7
397
24 - - 20.7
394
24 - - 48.7
398
24
3D
3f5rA00 - 68.9
396
24 - - 91.2
400
23 - - 28.8
401
23 - - 34.8
399
23 - - 36.7
402
23 - - 73.8
404
22 - - 87.3
406
22 - - 87.0
405
22 - - 91.3
407
22 - - 17.4
403
22 - - 71.0
410
21 - - 30.2
415
21 - - 10.0
417
21 - - 1.0
413
21 - - 21.4
425
21
3D
2lydA00 - 70.1
442
21
3D
3ulcA01 - 71.7
412
21 - - 57.9
408
PH
21 - - 51.7
416
21 - - 19.3
414
21 - - 13.7
409
21 - - 61.5
411
21 - - 46.6
424
20 - - 20.8
419
20 - - 4.3
421
20 - - 32.5
418
20 - - 42.2
423
PIK-H1
20 - - 12.2
422
20 - - 13.2
420
20 - - 10.4
430
19 - - 15.7
432
19 - - 8.2
434
19 - - 45.7
431
19 - - 70.2
427
19 - - 82.4
426
19 - - 68.6
428
19 - - 53.3
429
19 - - 15.3
433
19 - - 23.4
454
18
3D
3wyfE00 - 81.5
438
18 - - 12.5
440
18 - - 19.4
443
18 - - 61.0
437
18 - - 18.6
436
18 - - 5.4
441
18 - - 82.4
439
18 - - 7.6
435
18 - - 31.6
451
17 - - 20.7
447
17 - - 72.4
444
17 - - 76.5
446
17 - - 65.2
449
17 - - 34.1
453
17 - - 73.3
452
Bem3
17 - - 76.7
445
17 - - 21.1
448
17 - - 75.6
450
17 - - 35.5
463
16 - - 23.5
458
16 - - 13.5
456
16 - - 19.4
461
16 - - 32.6
465
16 - - 84.5
459
16 - - 82.5
455
16 - - 74.5
457
16 - - 88.3
460
16 - - 49.3
462
16 - - 10.8
464
16 - - 11.5
468
15 - - 15.1
475
15 - - 16.7
477
15 - - 22.5
479
15 - - 94.7
467
15 - - 17.7
474
15 - - 14.7
472
15 - - 18.1
470
15 - - 37.9
476
15 - - 4.6
469
15 - - 30.9
471
15 - - 5.0
478
Scaffold protein
15 - - 22.1
466
15 - - 31.0
473
15 - - 20.0
495
14 - - 16.7
486
14 - - 72.0
480
14 - - 50.6
493
14 - - 14.0
501
14 - - 21.7
490
14 - - 23.1
481
14 - - 12.8
503
14 - - 54.9
491
14 - - 2.9
485
14 - - 71.3
488
14 - - 66.2
496
14 - - 66.6
498
14 - - 21.4
500
14 - - 19.1
492
14 - - 18.4
489
14 - - 23.0
502
14 - - 62.3
497
14 - - 52.8
487
14 - - 52.6
494
14 - - 27.0
482
14 - - 31.2
499
14 - - 19.4
512
13 - - 19.3
508
13 - - 17.3
506
13 - - 20.5
510
13 - - 19.2
520
13
3D
1fhoA00 - 16.3
505
13 - - 16.3
509
13 - - 38.5
507
13 - - 10.6
513
13 - - 46.0
511
13 - - 11.0
504
13 - - 6.1
517
Necap-2
12 - - 12.6
515
12 - - 70.0
519
12 - - 70.6
526
12 - - 46.8
524
12 - - 74.7
522
12 - - 14.1
516
12 - - 7.7
716
12
3D
4dx9m00 - 22.5
523
12 - - 21.8
525
12 - - 41.4
514
12 - - 76.7
521
Cnk
12 - - 16.2
518
12 - - 71.7
540
11 - - 82.0
536
11 - - 83.3
573
11
3D
4iapB01 - 34.1
534
tre-2/USP6, BUB2, cdc16
11 - - 41.3
539
11 - - 12.5
532
11 - - 55.9
537
11 - - 21.6
529
11 - - 37.0
530
11 - - 23.9
527
11 - - 34.0
535
11 - - 73.5
824
11
3D
1k5gK00 - 32.3
533
11 - - 27.0
585
11
3D
3voqB00 - 25.4
555
11
3D
3zvrA03 - 9.1
538
11 - - 9.5
531
11 - - 3.3
528
11 - - 13.9
560
10 - - 60.8
558
Tre-2/Bub2/Cdc16
10 - - 75.6
545
10 - - 6.9
542
10 - - 1.7
556
10 - - 10.0
549
10 - - 52.6
554
10 - - 15.5
552
Tre-2/Bub2/Cdc16
10 - - 16.3
564
10 - - 92.9
563
10 - - 81.9
544
10 - - 13.6
546
10 - - 7.1
561
Protein4.1-ezrin-radixin-moesin
10 - - 49.7
550
10 - - 81.6
559
10 - - 21.1
548
10 - - 18.9
541
10 - - 15.9
557
Protein4.1-ezrin-radixin-moesin
10 - - 22.6
543
10 - - 9.9
553
10 - - 10.3
562
10 - - 83.3
551
10 - - 20.7
547
Mammalian Tumor Invasion And Metastasis factor
10 - - 15.5
578
9 - - 27.1
571
9 - - 6.8
1123
9
3D
5n2vD00 - 1.6
569
9 - - 9.8
586
9 - - 42.3
581
9 - - 9.6
574
9 - - 0.0
566
9 - - 4.9
583
9 - - 18.4
584
9 - - 17.5
576
9 - - 37.0
570
9 - - 6.9
580
9 - - 11.2
572
9 - - 3.5
579
9 - - 37.1
567
9 - - 72.1
568
9 - - 17.1
582
9 - - 2.4
575
9 - - 13.7
565
9 - - 17.9
587
Protein4.1-ezrin-radixin-moesin
9 - - 9.3
577
9 - - 82.9
594
8 - - 4.5
606
8 - - 14.6
588
8 - - 23.0
604
8 - - 7.8
614
8 - - 0.9
591
8 - - 14.8
598
PH
8 - - 17.2
602
8 - - 82.9
612
8 - - 2.0
608
8 - - 12.3
714
8
3D
4k81G02 - 22.1
600
8 - - 47.1
592
8 - - 20.3
597
8 - - 15.9
595
8 - - 17.4
605
8 - - 0.0
607
8 - - 0.0
590
8 - - 22.0
617
8 - - 94.5
610
8 - - 8.7
615
8 - - 75.2
589
8 - - 37.1
603
8 - - 8.8
611
8 - - 10.1
593
8 - - 8.7
616
8 - - 54.5
599
8 - - 42.9
609
8 - - 3.9
601
8 - - 78.5
596
8 - - 12.6
613
Tre-2/Bub2/Cdc16
8 - - 80.9
634
7 - - 1.2
638
7 - - 72.2
652
7 - - 4.5
633
7 - - 2.3
646
Tre-2/Bub2/Cdc16
7 - - 10.7
626
7 - - 13.8
649
7 - - 4.7
648
7 - - 4.3
642
7 - - 18.1
619
7 - - 33.7
621
7 - - 44.4
657
7 - - 3.9
623
7 - - 80.7
628
7 - - 9.4
630
7 - - 14.8
636
7 - - 12.8
625
7 - - 11.4
654
7 - - 15.7
655
Protein4.1-ezrin-radixin-moesin
7 - - 3.3
627
7 - - 1.9
653
7 - - 11.2
637
Tre-2/Bub2/Cdc16
7 - - 72.4
644
7 - - 6.8
650
7 - - 5.8
651
7 - - 10.0
629
7 - - 3.8
632
7 - - 10.0
645
7 - - 0.0
635
7 - - 0.0
620
7 - - 27.3
622
7 - - 43.3
647
7 - - 16.7
641
7 - - 8.8
640
7 - - 13.3
624
7 - - 74.0
656
7 - - 71.1
639
7 - - 53.6
643
7 - - 4.1
631
7 - - 6.1
618
PH
7 - - 30.3
661
6 - - 2.1
678
6 - - 17.0
666
6 - - 27.4
660
6 - - 1.0
671
6 - - 28.2
663
6 - - 15.9
658
6 - - 56.4
659
6 - - 15.0
682
Actin cytoskeleton modulator
6 - - 22.4
665
6 - - 67.6
681
6 - - 12.2
673
6 - - 14.5
667
6 - - 7.8
670
6 - - 48.1
675
6 - - 13.5
662
6 - - 10.6
683
6 - - 7.5
672
6 - - 9.5
677
6 - - 1.4
664
6 - - 33.6
674
6 - - 2.3
680
6 - - 1.0
679
6 - - 4.3
668
6 - - 43.5
669
6 - - 72.0
676
6 - - 0.0
695
5 - - 0.0
684
5 - - 79.5
706
A4
5 - - 20.4
686
5 - - 12.8
690
5 - - 69.8
700
5 - - 89.2
708
5 - - 11.0
710
5 - - 81.0
692
5 - - 1.5
689
5 - - 35.9
704
5 - - 10.5
698
5 - - 47.1
701
5 - - 89.7
711
5 - - 92.3
702
5 - - 20.3
696
5 - - 0.0
712
5 - - 38.3
685
5 - - 2.2
694
5 - - 14.8
691
5 - - 92.6
709
5 - - 84.8
699
5 - - 73.1
687
5 - - 4.6
688
5 - - 26.5
693
5 - - 11.5
705
5 - - 8.3
697
5 - - 3.2
707
5 - - 11.0
713
5 - - 57.7
703
5 - - 11.7
722
4 - - 5.4
728
4 - - 12.6
742
4 - - 12.6
758
4 - - 45.9
734
4 - - 86.1
746
4 - - 7.5
744
4 - - 0.0
724
4 - - 10.8
756
4 - - 35.4
717
4 - - 75.2
736
4 - - 89.0
727
4 - - 7.5
754
4 - - 76.9
731
4 - - 12.7
738
4 - - 9.6
733
4 - - 38.2
748
4 - - 15.3
741
4 - - 3.7
729
4 - - 5.1
735
4 - - 82.0
737
4 - - 83.7
739
4 - - 22.0
715
4 - - 41.4
743
4 - - 9.8
720
4 - - 10.3
723
4 - - 11.4
752
4 - - 74.3
759
4 - - 79.5
718
4 - - 82.9
751
4 - - 9.4
725
4 - - 8.1
757
4 - - 78.9
745
4 - - 4.2
730
4 - - 18.7
732
4 - - 3.6
747
4 - - 13.1
740
4 - - 23.8
719
4 - - 71.3
750
4 - - 5.0
755
4 - - 81.9
753
4 - - 5.6
726
4 - - 0.0
749
Vps36
4 - - 11.0
721
4 - - 77.4
798
Tre-2/Bub2/Cdc16
3 - - 0.0
784
3 - - 0.0
762
3 - - 37.9
773
3 - - 9.2
796
3 - - 3.8
775
3 - - 11.3
764
3 - - 70.4
810
RhoGAP
3 - - 6.1
806
3 - - 2.1
815
3 - - 36.4
766
3 - - 2.9
788
3 - - 5.3
782
GEF
3 - - 2.1
809
3 - - 4.3
781
3 - - 13.6
811
3 - - 7.8
819
3 - - 15.0
776
3 - - 10.8
801
3 - - 2.7
780
3 - - 16.9
817
3 - - 77.7
768
3 - - 9.6
761
RanBP
3 - - 63.7
823
3 - - 51.8
771
3 - - 7.9
808
3 - - 3.2
821
3 - - 59.5
763
3 - - 53.4
793
Capping, ARp2/3, Myosin I Linker protein
3 - - 9.7
799
3 - - 19.8
767
3 - - 10.0
805
3 - - 0.0
783
3 - - 0.0
789
3 - - 2.9
772
3 - - 0.0
778
3 - - 12.7
765
3 - - 72.2
800
3 - - 3.9
813
3 - - 0.0
816
3 - - 1.1
791
3 - - 3.0
787
3 - - 19.5
769
3 - - 9.3
803
3 - - 7.9
790
3 - - 1.1
797
3 - - 0.0
818
3 - - 59.1
795
3 - - 1.2
812
3 - - 13.4
794
3 - - 7.1
786
RanBP
3 - - 71.8
820
3 - - 30.5
774
3 - - 15.4
770
3 - - 1.1
804
3 - - 0.7
777
3 - - 1.4
785
3 - - 34.7
822
3 - - 22.5
779
3 - - 2.3
792
3 - - 0.0
814
3 - - 10.7
760
3 - - 14.6
802
3 - - 1.5
807
3 - - 12.5
882
2 - - 0.0
898
2 - - 0.0
1031
2 - - 36.8
978
2 - - 2.5
889
2 - - 0.0
861
2 - - 0.0
982
2 - - 8.8
825
2 - - 0.0
917
2 - - 24.1
966
2 - - 0.0
992
2 - - 0.9
834
2 - - 0.0
1000
2 - - 7.8
943
2 - - 22.9
999
2 - - 0.0
1022
2 - - 0.0
953
2 - - 8.9
875
2 - - 0.0
906
2 - - 0.0
927
2 - - 45.3
874
2 - - 0.0
975
2 - - 0.0
1033
2 - - 0.0
1026
2 - - 42.1
844
2 - - 31.9
919
2 - - 37.7
888
2 - - 1.1
1011
2 - - 0.0
1019
2 - - 0.0
990
2 - - 0.0
932
2 - - 13.7
860
2 - - 0.0
856
2 - - 0.0
961
2 - - 3.1
977
2 - - 1.4
1001
2 - - 0.9
854
2 - - 9.4
969
2 - - 0.0
877
2 - - 0.0
984
Vps36
2 - - 0.0
946
2 - - 19.0
941
2 - - 18.7
951
2 - - 4.7
832
2 - - 0.0
828
2 - - 22.3
872
2 - - 0.0
988
2 - - 1.4
865
2 - - 0.0
904
2 - - 0.0
930
2 - - 41.0
886
2 - - 0.0
1028
2 - - 41.7
939
2 - - 21.1
913
2 - - 11.3
894
2 - - 0.0
858
2 - - 0.0
954
2 - - 9.9
985
2 - - 0.0
830
2 - - 0.0
971
2 - - 0.0
847
2 - - 38.3
1003
2 - - 0.0
1029
2 - - 0.0
890
2 - - 8.8
922
2 - - 41.4
841
2 - - 16.1
936
2 - - 20.4
867
AFU_orthologue AFUA_3G13830
2 - - 0.0
1036
2 - - 44.1
928
2 - - 0.0
878
2 - - 0.0
997
2 - - 8.7
892
2 - - 10.5
1018
2 - - 15.3
1007
2 - - 0.0
998
2 - - 0.0
987
2 - - 0.0
908
2 - - 3.9
903
ARHGEF chondrocyte-derived
2 - - 39.1
845
2 - - 39.4
973
2 - - 8.0
915
2 - - 28.8
974
2 - - 0.0
963
2 - - 1.1
980
2 - - 11.5
958
2 - - 5.2
995
2 - - 0.0
837
2 - - 13.0
1030
2 - - 12.9
883
2 - - 0.0
1024
2 - - 41.7
864
2 - - 9.7
1016
2 - - 0.0
925
2 - - 43.5
840
2 - - 27.5
945
2 - - 23.4
959
2 - - 0.0
1020
2 - - 0.9
846
2 - - 41.2
1021
2 - - 44.4
934
2 - - 14.5
948
2 - - 8.6
968
2 - - 0.0
833
2 - - 0.0
926
2 - - 44.1
859
2 - - 0.0
876
2 - - 5.7
933
2 - - 9.8
993
2 - - 0.0
950
2 - - 2.1
1025
2 - - 41.1
1015
2 - - 12.4
976
2 - - 3.6
940
2 - - 20.8
1012
2 - - 9.7
835
2 - - 5.5
1032
2 - - 37.7
901
2 - - 10.7
1035
2 - - 38.2
862
2 - - 0.8
881
2 - - 0.0
897
2 - - 3.7
1002
2 - - 0.0
914
2 - - 21.7
965
2 - - 3.1
851
2 - - 6.4
916
2 - - 28.5
868
2 - - 3.8
983
2 - - 6.5
853
Dictyostelium Suppressor of MEK null
2 - - 10.1
911
2 - - 11.0
907
2 - - 1.3
895
2 - - 25.3
1006
2 - - 1.0
1034
2 - - 34.2
996
2 - - 0.0
956
2 - - 2.2
947
2 - - 1.8
920
2 - - 30.7
887
2 - - 6.6
869
2 - - 4.8
918
2 - - 13.6
1014
2 - - 0.0
843
2 - - 41.0
991
2 - - 1.7
931
2 - - 43.1
967
2 - - 0.0
979
2 - - 6.6
1005
2 - - 0.0
960
2 - - 0.0
826
2 - - 0.0
850
Src homology 2 domain-containing
2 - - 3.5
1004
2 - - 0.0
891
2 - - 0.0
937
2 - - 23.0
921
2 - - 34.0
1013
2 - - 11.0
994
2 - - 0.0
849
2 - - 0.0
842
2 - - 39.5
899
2 - - 4.4
944
2 - - 24.3
957
2 - - 0.0
970
2 - - 0.0
1017
2 - - 41.1
855
2 - - 0.0
831
2 - - 0.0
880
2 - - 0.0
986
2 - - 6.3
1008
2 - - 0.0
1027
2 - - 41.6
871
2 - - 9.5
902
2 - - 27.9
827
2 - - 23.4
905
2 - - 9.8
866
2 - - 0.0
910
2 - - 4.3
893
2 - - 0.0
838
Nuclear import/export
2 - - 24.8
870
2 - - 2.3
896
2 - - 40.5
962
2 - - 0.0
836
2 - - 13.4
955
2 - - 11.1
942
2 - - 22.2
912
2 - - 7.5
923
2 - - 41.9
981
2 - - 0.0
857
2 - - 0.0
1010
2 - - 0.0
964
2 - - 6.8
935
2 - - 16.7
1023
2 - - 42.2
924
2 - - 38.8
885
2 - - 3.7
884
2 - - 2.2
863
2 - - 0.9
829
2 - - 0.0
952
2 - - 0.0
989
2 - - 0.0
873
2 - - 9.7
852
2 - - 6.4
879
2 - - 0.0
938
2 - - 15.9
929
2 - - 42.5
949
2 - - 0.0
839
2 - - 27.5
1009
2 - - 2.4
909
2 - - 6.7
848
2 - - 14.9
900
2 - - 0.0
972
2 - - 0.0
1049
1 - - 0.0
1050
1 - - 0.0
1178
1 - - 0.0
1387
1 - - 0.0
1273
1 - - 0.0
1364
1 - - 0.0
1250
1 - - 0.0
1363
1 - - 0.0
1109
1 - - 0.0
1244
1 - - 0.0
1233
1 - - 0.0
1162
1 - - 0.0
1214
1 - - 0.0
1190
1 - - 0.0
1171
1 - - 0.0
1345
1 - - 0.0
1322
1 - - 0.0
1172
1 - - 0.0
1259
1 - - 0.0
1216
1 - - 0.0
1135
1 - - 0.0
1203
1 - - 0.0
1068
1 - - 0.0
1354
1 - - 0.0
1048
1 - - 0.0
1278
1 - - 0.0
1381
1 - - 0.0
1061
1 - - 0.0
1396
1 - - 0.0
1375
1 - - 0.0
1168
1 - - 0.0
1180
1 - - 0.0
1185
1 - - 0.0
1130
1 - - 0.0
1315
1 - - 0.0
1266
1 - - 0.0
1292
1 - - 0.0
1356
1 - - 0.0
1153
RalGDS/AF-6
1 - - 0.0
1336
1 - - 0.0
1089
1 - - 0.0
1084
1 - - 0.0
1144
1 - - 0.0
1197
1 - - 0.0
1349
1 - - 0.0
1247
1 - - 0.0
1309
1 - - 0.0
1260
1 - - 0.0
1320
1 - - 0.0
1390
1 - - 0.0
1268
1 - - 0.0
1372
1 - - 0.0
1161
1 - - 0.0
1285
1 - - 0.0
1380
1 - - 0.0
1242
1 - - 0.0
1107
1 - - 0.0
1208
1 - - 0.0
1383
1 - - 0.0
1201
1 - - 0.0
1074
1 - - 0.0
1195
1 - - 0.0
1063
1 - - 0.0
1327
1 - - 0.0
1274
1 - - 0.0
1283
1 - - 0.0
1220
1 - - 0.0
1331
1 - - 0.0
1149
1 - - 0.0
1305
1 - - 0.0
1087
1 - - 0.0
1288
1 - - 0.0
1238
1 - - 0.0
1229
1 - - 0.0
1338
1 - - 0.0
1182
1 - - 0.0
1076
1 - - 0.0
1174
1 - - 0.0
1141
1 - - 0.0
1128
1 - - 0.0
1155
1 - - 0.0
1361
1 - - 0.0
1313
1 - - 0.0
1373
1 - - 0.0
1302
1 - - 0.0
1112
1 - - 0.0
1397
1 - - 0.0
1294
1 - - 0.0
1358
1 - - 0.0
1156
1 - - 0.0
1218
GEF
1 - - 0.0
1193
1 - - 0.0
1404
1 - - 0.0
1106
1 - - 0.0
1402
1 - - 0.0
1146
1 - - 0.0
1333
1 - - 0.0
1184
1 - - 0.0
1207
1 - - 0.0
1318
1 - - 0.0
1116
1 - - 0.0
1329
1 - - 0.0
1098
1 - - 0.0
1059
1 - - 0.0
1189
1 - - 0.0
1177
1 - - 0.0
1127
1 - - 0.0
1298
1 - - 0.0
1269
1 - - 0.0
1359
1 - - 0.0
1101
1 - - 0.0
1166
1 - - 0.0
1165
1 - - 0.0
1378
1 - - 0.0
1054
1 - - 0.0
1289
Krev interaction trapped/cerebral cavernous malformation 1
1 - - 0.0
1282
1 - - 0.0
1311
1 - - 0.0
1044
1 - - 0.0
1072
1 - - 0.0
1394
1 - - 0.0
1350
1 - - 0.0
1391
1 - - 0.0
1277
1 - - 0.0
1086
1 - - 0.0
1240
1 - - 0.0
1092
1 - - 0.0
1347
1 - - 0.0
1078
1 - - 0.0
1243
1 - - 0.0
1253
1 - - 0.0
1265
1 - - 0.0
1196
1 - - 0.0
1114
1 - - 0.0
1223
1 - - 0.0
1316
1 - - 0.0
1368
1 - - 0.0
1254
1 - - 0.0
1234
1 - - 0.0
1314
1 - - 0.0
1125
1 - - 0.0
1188
1 - - 0.0
1186
1 - - 0.0
1280
1 - - 0.0
1058
1 - - 0.0
1324
1 - - 0.0
1150
1 - - 0.0
1096
1 - - 0.0
1335
1 - - 0.0
1191
1 - - 0.0
1340
1 - - 0.0
1231
1 - - 0.0
1119
1 - - 0.0
1249
1 - - 0.0
1046
1 - - 0.0
1142
1 - - 0.0
1291
1 - - 0.0
1052
1 - - 0.0
1179
1 - - 0.0
1271
1 - - 0.0
1104
1 - - 0.0
1406
1 - - 0.0
1133
1 - - 0.0
1118
1 - - 0.0
1307
1 - - 0.0
1301
1 - - 0.0
1212
1 - - 0.0
1164
1 - - 0.0
1081
1 - - 0.0
1094
1 - - 0.0
1225
1 - - 0.0
1205
1 - - 0.0
1287
1 - - 0.0
1159
1 - - 0.0
1367
1 - - 0.0
1226
1 - - 0.0
1256
1 - - 0.0
1070
1 - - 0.0
1170
1 - - 0.0
1042
1 - - 0.0
1169
1 - - 0.0
1065
1 - - 0.0
1312
1 - - 0.0
1257
1 - - 0.0
1263
1 - - 0.0
1296
1 - - 0.0
1303
1 - - 0.0
1398
1 - - 0.0
1145
1 - - 0.0
1246
1 - - 0.0
1083
1 - - 0.0
1110
1 - - 0.0
1293
1 - - 0.0
1357
1 - - 0.0
1152
1 - - 0.0
1131
1 - - 0.0
1090
1 - - 0.0
1308
1 - - 0.0
1374
1 - - 0.0
1270
1 - - 0.0
1389
1 - - 0.0
1202
1 - - 0.0
1040
1 - - 0.0
1138
1 - - 0.0
1232
1 - - 0.0
1267
1 - - 0.0
1386
1 - - 0.0
1056
1 - - 0.0
1215
1 - - 0.0
1173
1 - - 0.0
1279
1 - - 0.0
1258
1 - - 0.0
1395
1 - - 0.0
1075
1 - - 0.0
1148
1 - - 0.0
1321
1 - - 0.0
1365
1 - - 0.0
1407
1 - - 0.0
1228
1 - - 0.0
1073
Fragment
1 - - 0.0
1342
1 - - 0.0
1103
1 - - 0.0
1062
1 - - 0.0
1129
1 - - 0.0
1143
1 - - 0.0
1355
1 - - 0.0
1261
1 - - 0.0
1339
1 - - 0.0
1352
1 - - 0.0
1310
1 - - 0.0
1239
1 - - 0.0
1140
1 - - 0.0
1181
1 - - 0.0
1245
1 - - 0.0
1067
1 - - 0.0
1400
1 - - 0.0
1388
1 - - 0.0
1295
1 - - 0.0
1111
1 - - 0.0
1154
1 - - 0.0
1210
1 - - 0.0
1157
1 - - 0.0
1284
1 - - 0.0
1330
1 - - 0.0
1160
1 - - 0.0
1221
1 - - 0.0
1200
1 - - 0.0
1122
1 - - 0.0
1108
1 - - 0.0
1275
1 - - 0.0
1053
1 - - 0.0
1209
1 - - 0.0
1362
1 - - 0.0
1371
1 - - 0.0
1198
1 - - 0.0
1077
1 - - 0.0
1136
1 - - 0.0
1175
1 - - 0.0
1272
1 - - 0.0
1299
1 - - 0.0
1236
1 - - 0.0
1326
1 - - 0.0
1088
1 - - 0.0
1382
1 - - 0.0
1176
1 - - 0.0
1039
1 - - 0.0
1337
1 - - 0.0
1115
1 - - 0.0
1038
1 - - 0.0
1344
1 - - 0.0
1064
1 - - 0.0
1099
1 - - 0.0
1217
1 - - 0.0
1346
1 - - 0.0
1045
1 - - 0.0
1360
1 - - 0.0
1069
1 - - 0.0
1224
1 - - 0.0
1370
1 - - 0.0
1306
1 - - 0.0
1328
1 - - 0.0
1091
1 - - 0.0
1392
1 - - 0.0
1080
1 - - 0.0
1281
1 - - 0.0
1113
1 - - 0.0
1317
1 - - 0.0
1325
1 - - 0.0
1286
1 - - 0.0
1237
1 - - 0.0
1264
1 - - 0.0
1252
1 - - 0.0
1037
1 - - 0.0
1057
1 - - 0.0
1147
Fragment
1 - - 0.0
1332
1 - - 0.0
1241
1 - - 0.0
1399
1 - - 0.0
1206
Goodpasture antigen
1 - - 0.0
1117
1 - - 0.0
1401
1 - - 0.0
1139
1 - - 0.0
1319
1 - - 0.0
1222
1 - - 0.0
1353
1 - - 0.0
1219
1 - - 0.0
1194
1 - - 0.0
1126
1 - - 0.0
1341
1 - - 0.0
1097
1 - - 0.0
1121
1 - - 0.0
1384
1 - - 0.0
1385
1 - - 0.0
1085
NECAP
1 - - 0.0
1403
1 - - 0.0
1051
1 - - 0.0
1304
1 - - 0.0
1102
1 - - 0.0
1211
1 - - 0.0
1379
1 - - 0.0
1376
1 - - 0.0
1167
1 - - 0.0
1393
1 - - 0.0
1235
1 - - 0.0
1343
1 - - 0.0
1213
1 - - 0.0
1093
1 - - 0.0
1199
1 - - 0.0
1300
1 - - 0.0
1158
1 - - 0.0
1079
1 - - 0.0
1248
1 - - 0.0
1041
1 - - 0.0
1297
1 - - 0.0
1366
1 - - 0.0
1043
1 - - 0.0
1255
1 - - 0.0
1082
1 - - 0.0
1066
1 - - 0.0
1071
1 - - 0.0
1348
1 - - 0.0
1137
1 - - 0.0
1227
1 - - 0.0
1120
1 - - 0.0
1105
1 - - 0.0
1187
1 - - 0.0
1334
1 - - 0.0
1251
1 - - 0.0
1192
1 - - 0.0
1095
1 - - 0.0
1183
1 - - 0.0
1262
1 - - 0.0
1290
1 - - 0.0
1132
1 - - 0.0
1369
1 - - 0.0
1151
1 - - 0.0
1204
1 - - 0.0
1047
1 - - 0.0
1055
1 - - 0.0
1276
1 - - 0.0
1124
1 - - 0.0
1230
1 - - 0.0
1163
1 - - 0.0
1323
1 - - 0.0
1405
1 - - 0.0
1060
1 - - 0.0
1134
1 - - 0.0
1100
1 - - 0.0
1377
1 - - 0.0
1351
1 - - 0.0