CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family cerebral cavernous malformations 2 protein-like

Enzyme Information

UniProtKB Entries (1)

Q9BSQ5
CCM2_HUMAN
Homo sapiens
Cerebral cavernous malformations 2 protein

PDB Structure

PDB 4WJ7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis for the Disruption of the Cerebral Cavernous Malformations 2 (CCM2) Interaction with Krev Interaction Trapped 1 (KRIT1) by Disease-associated Mutations.
Fisher, O.S., Liu, W., Zhang, R., Stiegler, A.L., Ghedia, S., Weber, J.L., Boggon, T.J.
J.Biol.Chem.