CATH / Gene3D

16 million protein domains classified into 2,626 superfamilies

What's New?

The CATH website has recently undergone a big overhaul. We really hope you find the new pages more useful, easier to use and quicker to load. Please get in touch and let us know what you think.

Searching CATH

Example pages

Latest News

New CATH web pages at ECCB 2012

CATH @ VIZBI 2013 March 21, 2013

"Evolution of Protein Architecture" - Dr Sillitoe presents the CATH resource at VIZBI (Harvard/MIT)

Latest Release

CATH v3.5 based on PDB dated September 20, 2011
173,536CATH Domains
2,626CATH Superfamilies
51,334PDBs

Gene3D v11 released March 18, 2012
1,639Cellular Genomes
1,016Viral Genomes
14,963,305Protein Sequences
16,297,076CATH Domain Predictions

Citing CATH

If you find this resource useful, please consider citing the reference that describes this work:

New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures.
Sillitoe I, Cuff AL, Dessailly BH, Dawson NL, Furnham N, Lee D, Lees JG, Lewis TE, Studer RA, Rentzsch R, Yeats C, Thornton JM, Orengo CA
Nucleic Acids Res. 2013 Jan