CATH / Gene3D

16 million protein domains classified into 2,626 superfamilies

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CATH @ VIZBI 2013 March 21, 2013

"Evolution of Protein Architecture" - Dr Sillitoe presents the CATH resource at VIZBI (Harvard/MIT)

Latest Release

CATH v3.5 based on PDB dated September 20, 2011
173,536CATH Domains
2,626CATH Superfamilies

Gene3D v11 released March 18, 2012
1,639Cellular Genomes
1,016Viral Genomes
14,963,305Protein Sequences
16,297,076CATH Domain Predictions

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New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures.
Sillitoe I, Cuff AL, Dessailly BH, Dawson NL, Furnham N, Lee D, Lees JG, Lewis TE, Studer RA, Rentzsch R, Yeats C, Thornton JM, Orengo CA
Nucleic Acids Res. 2013 Jan