CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family Vav guanine nucleotide exchange factor 2

Enzyme Information

UniProtKB Entries (2)

P27870
VAV_MOUSE
Mus musculus
Proto-oncogene vav
P63000
RAC1_HUMAN
Homo sapiens
Ras-related C3 botulinum toxin substrate 1

PDB Structure

PDB 2VRW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crucial Structural Role for the Ph and C1 Domains of the Vav1 Exchange Factor.
Rapley, J., Tybulewicz, V., Rittinger, K.
Embo Rep.