CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family mRNA-decapping enzyme 1B

Enzyme Information

UniProtKB Entries (1)

E1JJR3
E1JJR3_DROME
Drosophila melanogaster
5'-3' exoribonuclease 1

PDB Structure

PDB 2LYD
External Links
Method SOLUTION NMR
Organism
Primary Citation
A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation.
Braun, J.E., Truffault, V., Boland, A., Huntzinger, E., Chang, C.T., Haas, G., Weichenrieder, O., Coles, M., Izaurralde, E.
Nat.Struct.Mol.Biol.