The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
SH2 domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
4293
2284
3D
1bm2A00 - 85.2
4354
2126
EC
3D
2knoA01 - 78.9
4228
2005
EC
3D
1a07A00 - 93.1
4366
1749
EC
3D
2b3oA01 - 89.1
4342
1485
EC
3D
1opkA02 - 98.8
4305
1466
3D
1h9oA00 - 97.5
4308
1270
EC
3D
2l3tA01 - 74.0
4276
960
EC
3D
2ge9A00 - 92.7
4233
890
EC
3D
1b47A03 - 88.6
4254
777
EC
3D
1bg1A04 - 80.1
4288
774
EC
3D
2mk2A00 - 85.4
4229
631
EC
3D
2hdvA00 - 77.8
4290
628
3D
2crhA01 - 91.6
4278
511
EC
3D
4ey0A02 - 91.7
4181
480
3D
1ju5A00 - 82.7
1631
455
EC
3D
1ayaA00 - 38.9
4295
425
3D
1y1uA04 - 91.0
4256
415
EC
3D
3eacA00 - 90.0
4189
400
3D
2izvA00 - 83.8
4119
384 - - 83.7
4214
376
EC
3D
2shpA02 - 81.4
4217
352 - - 91.1
4294
320
3D
2eo6A01 - 93.2
4173
317
3D
3cxlA01 - 61.0
4212
297
EC
3D
1a81A01 - 85.8
4210
297
EC
3D
2kk6A00 - 76.0
4234
246
EC
3D
2dlyA00 - 83.2
98
225 - - 69.8
4268
215
EC
- - 94.7
4136
215
EC
3D
1a81A03 - 84.4
4195
179 - - 81.3
1340
136 - - 60.3
151
134
3D
2vifA01 - 29.2
4129
131 - - 38.5
2646
125
3D
2cr4A01 - 72.0
2736
123 - - 50.4
596
113 - - 65.5
4167
107
3D
1milA00 - 52.7
4148
97 - - 58.1
4222
96 - - 79.5
1132
92
EC
3D
1jwoA00 - 44.7
100
90
3D
2c9wA01 - 51.5
4145
87 - - 40.8
1435
86 - - 39.9
959
83 - - 61.5
4275
82 - - 70.2
4122
79
3D
3mazA00 - 54.5
4126
75
EC
3D
2eobA01 - 55.1
1889
75
EC
3D
2oq1A03 - 45.6
4137
74 - - 47.4
1894
72 - - 38.7
907
71 - - 41.4
1566
69
3D
4m4zA02 - 42.2
4097
62
EC
- - 40.3
4140
61
EC
- - 57.2
4156
57
3D
2el8A01 - 60.1
282
55
EC
3D
2b3oA02 - 36.2
4364
52
EC
- - 79.4
1142
52
EC
- - 10.2
2155
44 - - 41.5
2348
41
EC
- - 23.7
2234
39 - - 26.1
1215
39 - - 34.1
1140
39
EC
- - 13.3
1905
27 - - 6.6
4144
24 - - 30.4
4322
22
EC
- - 79.7
3263
20
EC
- - 14.6
1475
19 - - 6.7
4187
18
3D
2cs0A01 - 42.3
656
18 - - 15.5
649
17 - - 8.4
4161
17
EC
- - 44.6
2487
17 - - 37.3
791
15 - - 14.3
4160
13
EC
- - 35.2
792
13
EC
- - 48.9
238
13 - - 24.0
2500
9 - - 5.3
4258
7 - - 48.6
58
6 - - 2.3
4333
5
EC
- - 65.2
174
5
EC
- - 15.3
3315
4
EC
- - 14.3
415
4
EC
- - 14.4
2191
4 - - 18.2
4292
4 - - 7.9
419
4
EC
- - 6.0
19
4 - - 4.3
4282
4
3D
2ci9A00 - 19.8
2375
3
EC
- - 9.9
3616
3 - - 10.8
2861
3
EC
- - 2.0
395
2 - - 14.5
2485
2
EC
- - 8.7
1845
2
EC
- - 0.0
2045
2 - - 0.0
1002
2
EC
- - 7.7
770
2
EC
- - 13.6
3835
2
EC
- - 13.2
2124
2
EC
- - 8.8
49
1 - - 0.0
2046
1
EC
- - 0.0
4082
1 - - 0.0
701
1
EC
- - 0.0
1512
1 - - 0.0
4363
1
EC
- - 0.0
4050
1
EC
- - 0.0