CATH Classification

Domain Context

CATH Clusters

Superfamily SH2 domain
Functional Family Non-specific protein-tyrosine kinase

Enzyme Information

2.7.10.2
Non-specific protein-tyrosine kinase.
based on mapping to UniProt P41240
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P41240
CSK_HUMAN
Homo sapiens
Tyrosine-protein kinase CSK

PDB Structure

PDB 3EAC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Combining biophysical methods to analyze the disulfide bond in SH2 domain of C-terminal Src kinase.
Liu, D., Cowburn, D.
Biophys Rep