CATH Superfamily 3.20.20.70

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Enzyme?	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
117579	4-Hydroxy-2-oxoglutarate aldolase / 2-dehydro-3-deoxyphosphogluconate aldolase	50613	EC	3D	1eunA00	-	89.4
120872	4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic	33335	EC	3D	3s5nA00	-	97.3
119827	Nadh:flavin oxidoreductase nadh oxidase	32813	EC	3D	1q45A00	-	91.6
120487	Dihydroorotate dehydrogenase quinone	27997	EC	3D	1d3gA00	-	90.2
120820	Imidazole glycerol phosphate synthase	27576	EC	3D	2lleA00	-	91.6
119626	3-keto-L-gulonate-6-phosphate decarboxylase UlaD	26908	EC	3D	1kv8A00	-	74.5
116748	Fructose-bisphosphate aldolase class 1	25778	EC		-	-	84.9
120777	tRNA-dihydrouridine synthase B protein	24431	EC	3D	3w9zA01	-	84.5
120512	IMP dehydrogenase., GMP reductase	23078	EC	3D	1b3oA00	-	84.7
120452	2-isopropylmalate synthase 2, mitochondrial	21188	EC	3D	3ivsA01	-	93.5
120783	Pyruvate carboxylase subunit B	21177	EC	3D	3bg3A02	-	93.9
120791	Triosephosphate isomerase /regucalcin fusion	20808	EC	3D	3q37A00	-	91.1
120782	Ribulose-phosphate 3-epimerase AFU_orthologue; AFUA_2G15190	20444	EC	3D	3ovpA00	-	90.9
120854	FO synthase subunit 2	19454	EC	3D	1r30A00	-	92.7
117610	Ethanolamine ammonia-lyase, large subunit	19157	EC	3D	3aboA03	-	85.8
120580	Fructose-bisphosphate aldolase, class II	17972	EC	3D	1b57A00	-	96.0
117135	Probable phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited	17109	EC	3D	1hfbA00	-	90.1
120702	Dual-specificity RNA methyltransferase RlmN	16681	EC	3D	3rf9A02	-	92.7
120825	Tryptophan synthase alpha chain	16653	EC	3D	1v7yA00	-	91.9
119975	Lipoyl synthase 2, mitochondrial	16377	EC		-	-	87.5
118627	Putative fructose-6-phosphate aldolase	15583	EC	3D	1l6wA00	-	87.2
120450	Pyridoxal phosphate biosynthetic protein	15368	EC	3D	1ho1A00	-	92.0
120593	Cyclic pyranopterin monophosphate synthase	15001	EC	3D	2fb2A00	-	93.0
119454	Delta-aminolevulinic acid dehydratase, chloroplastic	14892	EC	3D	1e51A00	-	95.7
120694	Deoxyribose-phosphate aldolase 2	14512	EC	3D	1jcjA00	-	95.2
119711	FMN-dependent L-lactate dehydrogenase protein	14323	EC	3D	1huvA00	-	90.3
120787	Dihydroorotate dehydrogenase, catalytic subunit	14311	EC	3D	5kswA00	-	93.4
120766	Indole-3-glycerol phosphate synthase 2	13782	EC	3D	3qjaA00	-	93.0
120721	Transaldolase AFU_orthologue AFUA_5G09230	13083	EC	3D	1f05A00	-	93.9
120901	Probable nicotinate-nucleotide pyrophosphorylase [carboxylating]	12997	EC	3D	2jbmA02	-	91.3
120922	Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative	12135	EC	3D	2f84A00	-	91.8
120607	Putative L-lysine 2,3-aminomutase	11122	EC	3D	2a5hA02	-	94.6
119956	Thiazole biosynthesis protein thiG	10442	EC	3D	1tygA00	-	96.3
119159	2-dehydro-3-deoxyphosphooctonate aldolase, putative, expressed	10138	EC	3D	1d9eA00	-	91.0
119619	Glutamate synthase, large subunit	9934	EC	3D	1ea0A03	-	94.2
120648	Hexulose-6-phosphate synthase and isomerase	9424	EC	3D	3iebA00	-	97.2
115667	Aldose-ketose isomerase YihS	8856	EC		-	-	40.5
119615	Pyridoxine biosynthesis protein PDX1	8847	EC	3D	5k2zA00	-	88.2
120345	Putative thiamine-phosphate synthase 2	7950	EC	3D	1g4eA00	-	90.8
120764	Oxidoreductase, 2-nitropropane dioxygenase family	7806	EC	3D	3bo9A00	-	91.2
118665	Glutamate synthase, large subunit	7651	EC	3D	1ea0A02	-	93.7
120359	Phosphomethylpyrimidine kinase, Thiamine-phosphate diphosphorylase	7442	EC		-	-	89.6
120976	3-dehydroquinate dehydratase, type I	7009	EC	3D	2gptA01	-	94.0
88382	2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase	6892	EC	3D	2v81A00	-	59.9
120507	2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase 1	6512	EC	3D	3gkfA00	-	95.6
119773	tRNA-dihydrouridine synthase A	6388	EC		-	-	93.2
118865	Bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	6007	EC	3D	1vr6A02	-	73.0
120722	Putative N-acetylmannosamine-6-phosphate 2-epimerase	5835	EC	3D	1y0eA00	-	98.5
116673	Tagatose 1,6-diphosphate aldolase	5719	EC	3D	3iv3A00	-	93.8
120367	Indole-3-glycerol-phosphate synthase., Phosphoribosylanthranilate isomerase	5584	EC	3D	1dl3A00	-	92.9
120251	Isopentenyl-diphosphate delta-isomerase, type 2	5530	EC	3D	1p0kA00	-	90.2
120938	Arylsulfatase regulator, anaerobic sulfatase-maturating enzyme	5371	EC	3D	4k36A00	-	92.7
120333	Probable alpha-galactosidase A	4978	EC	3D	1r46A01	-	85.3
120732	Anaerobic ribonucleoside-triphosphate reductase-activating protein	4772	EC		-	-	96.5
120939	Glucose-6-phosphate isomerase / transaldolase	4767	EC	3D	3r5eA00	-	96.2
118723	Fructose-bisphosphate aldolase 1, chloroplastic	4479	EC	3D	1aldA00	-	85.6
120731	Probable alpha-galactosidase C	4286	EC	3D	2yfnA02	-	97.5
120633	Tryptophan biosynthesis protein trpCF	4052	EC	3D	1piiA02	-	93.4
120253	Orotidine 5'-phosphate decarboxylase	3808	EC		-	-	92.7
120894	Thiazole biosynthesis protein ThiH	3709	EC	3D	3t7vA00	-	95.8
119582	Indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase	3684	EC	3D	1jcmP00	-	92.9
117165	Fructose-bisphosphate aldolase class 1	3016	EC		-	-	82.2
116116	Probable tRNA-dihydrouridine synthase 2	2493			-	-	61.0
120439	Thiamine-phosphate synthase	2321	EC		-	-	95.9
60593	Triosephosphate isomerase	2189	EC	3D	1spqA00	-	97.5
115651	D-tagatose-1,6-bisphosphate aldolase subunit GatZ	1981	EC	3D	2fiqA01	-	89.9
119698	Uncharacterised protein	1934	EC	3D	3v75A01	-	92.0
34734	Anaerobic sulfatase maturase	1852			-	-	28.6
120225	N- 5'-phosphoribosyl	1730	EC		-	-	91.0
120179	Uridine monophosphate synthetase isoform I	1701	EC	3D	2eawA00	-	83.2
120952	1- 5-phosphoribosyl 5-phosphoribosylamino	1699	EC	3D	2agkA00	-	81.9
120255	Thiamine-phosphate synthase	1699	EC	3D	3o63A00	-	86.2
120838	Tryptophan synthase, beta subunit	1657	EC	3D	5lheA00	-	92.5
120246	GPI-anchored cell-surface protein hyaluronidase 2	1617	EC	3D	2pe4A00	-	83.2
118423	Coenzyme PQQ synthesis protein E	1592	EC		-	-	97.1
119732	Thiamine-phosphate synthase 2	1196	EC		-	-	76.4
117972	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase	1144	EC		-	-	84.6
55559	Triosephosphate isomerase	1125	EC	3D	2dp3A00	-	94.3
86789	Putative epimerase KpLE2 phage-like element	797	EC		-	-	0.6
120273	N- 5'-phosphoribosyl	795	EC		-	-	90.5
79566	Putative epimerase LsrE	768	EC		-	-	6.3
120556	Thiamine-phosphate synthase	621	EC	3D	1xi3A00	-	96.8
120206	Triosephosphate isomerase	619	EC	3D	2h6rA00	-	95.5
119653	Fatty acid synthase beta subunit	606	EC	3D	2uv8G04	-	90.5
116492	Inositol-5-monophosphate dehydrogenase	598	EC		-	-	69.3
120278	N- 5'-phosphoribosyl	513	EC		-	-	90.9
120913	Putative alpha-galactosidase 8	511	EC		-	-	89.5
120666	Multifunctional tryptophan biosynthesis protein	509	EC		-	-	94.3
118248	Nitrogenase cofactor biosynthesis protein NifB	507			-	-	92.7
120583	7-carboxy-7-deazaguanine synthase	494	EC		-	-	84.1
120574	N- 5'-phosphoribosyl	409	EC		-	-	94.0
106829	Molybdenum transport protein ModD	399	EC		-	-	6.5
104754	Nicotinate-nucleotide diphosphorylase	380	EC	3D	2b7nA02	-	34.4
117982	Thiamine-phosphate synthase	370	EC		-	-	63.2
63882	Uncharacterized protein	309			-	-	15.6
119575	Pseudaminic acid synthase	296	EC		-	-	60.0
120927	7-carboxy-7-deazaguanine synthase	283	EC		-	-	93.8
58421	Molybdenum cofactor biosynthesis protein 1	276	EC		-	-	84.7
120746	Sporulation putative phosphosulfolactate synthase YitD	219	EC	3D	1qwgA00	-	94.6
1828	Glutamate synthase family protein	213	EC		-	-	38.8
119834	Phosphoribosyl-anthranilate isomerase	211	EC		-	-	85.2
1148	IMP Inosine monophosphate	207	EC	3D	1nf7A00	-	77.9
115431	Radical S-adenosyl methionine domain-containing protein 2	191			-	-	83.5
119618	Keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase	189	EC	3D	1mxsA00	-	57.5
73503	Phosphomethylpyrimidine synthase	165	EC		-	-	10.3
120831	3-dehydroquinate synthase	149	EC		-	-	94.7
118828	Sialic acid synthase	146	EC		-	-	84.1
119564	Triosephosphate isomerase	144	EC		-	-	69.6
120571	Probable thiamine biosynthetic bifunctional enzyme, chloroplastic	137	EC		-	-	91.0
119485	3-keto-5-aminohexanoate cleavage enzyme	121	EC	3D	2y7dA00	-	79.0
114399	Probable N-methylproline demethylase	113	EC		-	-	56.3
74818	Thiamine biosynthetic bifunctional enzyme	108	EC		-	-	0.0
93723	Thiamine-phosphate synthase	105	EC		-	-	36.2
88024	Thiamine-phosphate synthase	102	EC		-	-	14.9
29738	Radical SAM protein YfkA	98	EC		-	-	14.3
60742	Triosephosphate isomerase	96	EC	3D	4y8fA00	-	29.3
89899	N- 5'-phosphoribosyl	96	EC		-	-	15.6
94996	4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconate aldolase	90	EC		-	-	5.2
120529	Probable galactinol--sucrose galactosyltransferase 2	84	EC		-	-	90.5
89603	Thiamine-phosphate synthase	83	EC		-	-	8.5
120928	N- 5'-phosphoribosyl	81	EC		-	-	97.1
120108	tRNA-dihydrouridine 20 P	74	EC		-	-	49.0
120929	7-carboxy-7-deazaguanine synthase	66	EC		-	-	91.5
97812	Radical SAM protein	58	EC		-	-	16.2
86786	Thiamine-phosphate synthase	57	EC		-	-	4.2
6637	Selenate reductase subunit YgfK	56	EC		-	-	82.6
118734	Thiamine-phosphate synthase	55	EC		-	-	28.8
120263	N- 5'-phosphoribosyl	53	EC		-	-	80.9
25844	Isopentenyl-diphosphate delta-isomerase, type II	52	EC		-	-	64.4
52976	Uncharacterized aldolase SSO3226	51	EC		-	-	7.8
118832	Polyunsaturated fatty acid synthase PfaD	44	EC		-	-	51.4
88100	Regulatory protein TenI	43	EC	3D	1yadA00	-	11.3
120497	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase	38	EC	3D	2yx0A00	-	69.3
41821	Nitronate monooxygenase	37	EC		-	-	3.0
92591	Bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase	37	EC		-	-	1.1
100470	2-keto-3-deoxygluconate-6-phosphate aldolase	36	EC		-	-	6.0
85727	Thiamine-phosphate synthase	33	EC		-	-	4.3
117376	Thiamine-phosphate synthase	33	EC		-	-	27.1
28297	Dihydrodipicolinate synthetase	31	EC	3D	3fkkA00	-	13.9
7435	Ferredoxin-dependent glutamate synthase	27	EC		-	-	2.4
120807	Radical SAM domain protein	27			-	-	95.7
52475	Orotidine 5'-phosphate decarboxylase	26	EC		-	-	16.8
56864	Triosephosphate isomerase 2	26	EC		-	-	11.9
120774	Thiamine-phosphate synthase	22	EC		-	-	80.1
88988	Thiamine-phosphate synthase	21	EC		-	-	20.1
120634	N- 5'-phosphoribosyl	21	EC		-	-	88.9
23166	4-hydroxy-2-oxovalerate aldolase domain-containing protein	20	EC		-	-	1.7
86336	Deoxyribose-phosphate aldolase	19	EC		-	-	13.8
87677	Thiamine-phosphate synthase	18	EC		-	-	4.7
120157	3-dehydroquinate dehydratase	18	EC		-	-	37.5
120713	Putative thiamine-phosphate synthase 2	18	EC		-	-	76.2
74243	Deoxyribose-phosphate aldolase	16	EC		-	-	0.0
79557	3-dehydroquinate dehydratase	16	EC		-	-	0.0
120117	Putative pyrophosphorylase ModD	14	EC		-	-	50.6
8375	NADH-dependent flavin oxidoreductase	13			-	-	2.9
86330	Phosphoribosylanthranilate isomerase	12	EC		-	-	20.3
90254	Thiamine-phosphate synthase	11	EC		-	-	9.4
86730	Thiamine-phosphate synthase	11	EC		-	-	4.2
33820	Orotidine 5'-phosphate decarboxylase	10	EC		-	-	16.3
90247	Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase	10	EC		-	-	1.9
117601	Thiamine-phosphate synthase	10	EC		-	-	7.4
119545	Heme d1 biosynthesis protein NirJ	10			-	-	33.7
116267	NADH:flavin oxidoreductase/NADH oxidase	9	EC		-	-	8.0
120537	N- 5'-phosphoribosyl	8	EC		-	-	37.6
24553	FMN-dependent 2-nitropropane dioxygenase	8	EC		-	-	1.8
92735	Putative KHG/KDPG aldolase	8	EC		-	-	8.1
2263	2-enoate reductase FldZ	8	EC		-	-	2.1
40492	2-nitropropane dioxygenase family	7			-	-	11.9
64323	Orotidine 5'-phosphate decarboxylase	6	EC		-	-	12.1
104382	FZO-like protein	5			-	-	9.5
120517	Thiamine-phosphate synthase	5	EC		-	-	11.2
86796	Thiamine-phosphate synthase	5	EC		-	-	1.0
76047	N- 5'-phosphoribosyl	4	EC		-	-	0.0
99066	2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase	4	EC		-	-	0.0
119650	Hypothetical chloroplast RF23	4			-	-	0.0
83484	3-dehydroquinate dehydratase	4	EC		-	-	0.0
39323	Kinase IolC	4			-	-	0.0
42384	Possible alpha-galactosidase	4			-	-	0.0
42266	Fructose-bisphosphate aldolase/6-deoxy-5-ketofructose 1-phosphate synthase	4	EC		-	-	14.2
120877	N- 5'-phosphoribosyl	3	EC		-	-	46.2
120856	Triosephosphate isomerase	3	EC		-	-	41.1
47232	Orotidine 5'-phosphate decarboxylase	3	EC		-	-	10.5
74801	Lysine 2,3-aminomutase YodO family protein	3	EC		-	-	9.5
80772	Thiamine-phosphate synthase	3	EC		-	-	5.2
48674	Orotidine 5'-phosphate decarboxylase	2	EC		-	-	0.0
120917	Uncharacterized methyltransferase PH0819	2			-	-	9.4
51924	Bifunctional enzyme PyrF/PyrE	2	EC		-	-	3.4
120491	N- 5'-phosphoribosyl	2	EC		-	-	33.9
119478	Indole-3-glycerol phosphate synthase	2	EC		-	-	30.0
16785	Isomalto-dextranase	2	EC		-	-	0.3
97590	Thiamine-phosphate synthase	2	EC		-	-	2.9
119519	Thiamine-phosphate synthase	2	EC		-	-	23.2
79089	Putative L-lysine 2,3-aminomutase aq_1632	2			-	-	6.4
75400	Thiamine biosynthesis multifunctional protein ThiED	2	EC		-	-	0.0
64355	Phosphosulfolactate synthase	2	EC		-	-	6.0
120490	Thiamine-phosphate synthase	2	EC		-	-	34.7
92272	Thiamine-phosphate synthase	2	EC		-	-	2.0
61478	Radical SAM domain protein	2			-	-	10.0
120519	Uncharacterized protein ycf23	1			-	-	0.0
89490	N- 5'-phosphoribosyl	1	EC		-	-	0.0
6002	Bile acid-inducible operon protein CD	1			-	-	0.0
113338	Indole-3-glycerol phosphate synthase	1	EC		-	-	0.0
88538	Thiamine-phosphate synthase	1	EC		-	-	0.0
91961	Thiamine-phosphate synthase	1	EC		-	-	0.0
120848	7-carboxy-7-deazaguanine synthase	1	EC		-	-	0.0
63233	Radical SAM domain protein	1			-	-	0.0
69248	1- 5-phosphoribosyl 5-phosphoribosylamino	1	EC		-	-	0.0
90252	Uncharacterized protein ycf23	1			-	-	0.0
80118	Thiamine biosynthesis multifunctional protein ThiED	1	EC		-	-	0.0
78558	N- 5'-phosphoribosyl	1	EC		-	-	0.0
90977	Thiamine-phosphate synthase	1	EC		-	-	0.0
62135	Putative Fe-S-cluster redox enzyme	1			-	-	0.0
3156	NADH-dependent flavin oxidoreductase	1			-	-	0.0
113822	Transaldolase	1	EC		-	-	0.0
36232	Tungsten-containing aldehyde ferredoxin oxidoreductase cofactor-modifying protein	1			-	-	0.0
2033	Glutamate synthase, homolog	1			-	-	0.0
84258	N- 5'-phosphoribosyl	1	EC		-	-	0.0
106775	Homocitrate synthase, omega subunit	1	EC		-	-	0.0
95730	Radical SAM domain protein	1			-	-	0.0
75430	Alpha-galactosidase 2	1			-	-	0.0
121015	Methanogenesis marker protein 10	1			-	-	0.0
88999	Radical SAM domain protein	1			-	-	0.0
74251	Multifunctional tryptophan biosynthesis protein	1	EC		-	-	0.0
113619	N- 5'-phosphoribosyl	1	EC		-	-	0.0
59950	Putative transcriptional regulatory protein y4pA	1			-	-	0.0