The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
117579
50613
EC
3D
1eunA00 - 89.4
120872
33335
EC
3D
3s5nA00 - 97.3
119827
32813
EC
3D
1q45A00 - 91.6
120487
quinone
27997
EC
3D
1d3gA00 - 90.2
120820
27576
EC
3D
2lleA00 - 91.6
119626
26908
EC
3D
1kv8A00 - 74.5
116748
25778
EC
- - 84.9
120777
24431
EC
3D
3w9zA01 - 84.5
120512
23078
EC
3D
1b3oA00 - 84.7
120452
21188
EC
3D
3ivsA01 - 93.5
120783
21177
EC
3D
3bg3A02 - 93.9
120791
20808
EC
3D
3q37A00 - 91.1
120782
AFU_orthologue; AFUA_2G15190
20444
EC
3D
3ovpA00 - 90.9
120854
19454
EC
3D
1r30A00 - 92.7
117610
19157
EC
3D
3aboA03 - 85.8
120580
17972
EC
3D
1b57A00 - 96.0
117135
17109
EC
3D
1hfbA00 - 90.1
120702
16681
EC
3D
3rf9A02 - 92.7
120825
16653
EC
3D
1v7yA00 - 91.9
119975
16377
EC
- - 87.5
118627
15583
EC
3D
1l6wA00 - 87.2
120450
15368
EC
3D
1ho1A00 - 92.0
120593
15001
EC
3D
2fb2A00 - 93.0
119454
14892
EC
3D
1e51A00 - 95.7
120694
14512
EC
3D
1jcjA00 - 95.2
119711
14323
EC
3D
1huvA00 - 90.3
120787
14311
EC
3D
5kswA00 - 93.4
120766
13782
EC
3D
3qjaA00 - 93.0
120721
AFU_orthologue AFUA_5G09230
13083
EC
3D
1f05A00 - 93.9
120901
12997
EC
3D
2jbmA02 - 91.3
120922
12135
EC
3D
2f84A00 - 91.8
120607
11122
EC
3D
2a5hA02 - 94.6
119956
10442
EC
3D
1tygA00 - 96.3
119159
10138
EC
3D
1d9eA00 - 91.0
119619
9934
EC
3D
1ea0A03 - 94.2
120648
9424
EC
3D
3iebA00 - 97.2
115667
8856
EC
- - 40.5
119615
8847
EC
3D
5k2zA00 - 88.2
120345
7950
EC
3D
1g4eA00 - 90.8
120764
7806
EC
3D
3bo9A00 - 91.2
118665
7651
EC
3D
1ea0A02 - 93.7
120359
7442
EC
- - 89.6
120976
7009
EC
3D
2gptA01 - 94.0
88382
6892
EC
3D
2v81A00 - 59.9
120507
6512
EC
3D
3gkfA00 - 95.6
119773
6388
EC
- - 93.2
118865
6007
EC
3D
1vr6A02 - 73.0
120722
5835
EC
3D
1y0eA00 - 98.5
116673
5719
EC
3D
3iv3A00 - 93.8
120367
5584
EC
3D
1dl3A00 - 92.9
120251
5530
EC
3D
1p0kA00 - 90.2
120938
5371
EC
3D
4k36A00 - 92.7
120333
4978
EC
3D
1r46A01 - 85.3
120732
4772
EC
- - 96.5
120939
4767
EC
3D
3r5eA00 - 96.2
118723
4479
EC
3D
1aldA00 - 85.6
120731
4286
EC
3D
2yfnA02 - 97.5
120633
4052
EC
3D
1piiA02 - 93.4
120253
3808
EC
- - 92.7
120894
3709
EC
3D
3t7vA00 - 95.8
119582
3684
EC
3D
1jcmP00 - 92.9
117165
3016
EC
- - 82.2
116116
2493 - - 61.0
120439
2321
EC
- - 95.9
60593
2189
EC
3D
1spqA00 - 97.5
115651
1981
EC
3D
2fiqA01 - 89.9
119698
1934
EC
3D
3v75A01 - 92.0
34734
1852 - - 28.6
120225
N-
5'-phosphoribosyl
1730
EC
- - 91.0
120179
1701
EC
3D
2eawA00 - 83.2
120952
1-
5-phosphoribosyl 5-phosphoribosylamino
1699
EC
3D
2agkA00 - 81.9
120255
1699
EC
3D
3o63A00 - 86.2
120838
1657
EC
3D
5lheA00 - 92.5
120246
1617
EC
3D
2pe4A00 - 83.2
118423
1592
EC
- - 97.1
119732
1196
EC
- - 76.4
117972
1144
EC
- - 84.6
55559
1125
EC
3D
2dp3A00 - 94.3
86789
797
EC
- - 0.6
120273
N-
5'-phosphoribosyl
795
EC
- - 90.5
79566
768
EC
- - 6.3
120556
621
EC
3D
1xi3A00 - 96.8
120206
619
EC
3D
2h6rA00 - 95.5
119653
606
EC
3D
2uv8G04 - 90.5
116492
598
EC
- - 69.3
120278
N-
5'-phosphoribosyl
513
EC
- - 90.9
120913
511
EC
- - 89.5
120666
509
EC
- - 94.3
118248
507 - - 92.7
120583
494
EC
- - 84.1
120574
N-
5'-phosphoribosyl
409
EC
- - 94.0
106829
399
EC
- - 6.5
104754
380
EC
3D
2b7nA02 - 34.4
117982
370
EC
- - 63.2
63882
309 - - 15.6
119575
296
EC
- - 60.0
120927
283
EC
- - 93.8
58421
276
EC
- - 84.7
120746
219
EC
3D
1qwgA00 - 94.6
1828
213
EC
- - 38.8
119834
211
EC
- - 85.2
1148
Inosine monophosphate
207
EC
3D
1nf7A00 - 77.9
115431
191 - - 83.5
119618
189
EC
3D
1mxsA00 - 57.5
73503
165
EC
- - 10.3
120831
149
EC
- - 94.7
118828
146
EC
- - 84.1
119564
144
EC
- - 69.6
120571
137
EC
- - 91.0
119485
121
EC
3D
2y7dA00 - 79.0
114399
113
EC
- - 56.3
74818
108
EC
- - 0.0
93723
105
EC
- - 36.2
88024
102
EC
- - 14.9
29738
98
EC
- - 14.3
60742
96
EC
3D
4y8fA00 - 29.3
89899
N-
5'-phosphoribosyl
96
EC
- - 15.6
94996
90
EC
- - 5.2
120529
84
EC
- - 90.5
89603
83
EC
- - 8.5
120928
N-
5'-phosphoribosyl
81
EC
- - 97.1
120108
20 P
74
EC
- - 49.0
120929
66
EC
- - 91.5
97812
58
EC
- - 16.2
86786
57
EC
- - 4.2
6637
56
EC
- - 82.6
118734
55
EC
- - 28.8
120263
N-
5'-phosphoribosyl
53
EC
- - 80.9
25844
52
EC
- - 64.4
52976
51
EC
- - 7.8
118832
44
EC
- - 51.4
88100
43
EC
3D
1yadA00 - 11.3
120497
38
EC
3D
2yx0A00 - 69.3
41821
37
EC
- - 3.0
92591
37
EC
- - 1.1
100470
36
EC
- - 6.0
85727
33
EC
- - 4.3
117376
33
EC
- - 27.1
28297
31
EC
3D
3fkkA00 - 13.9
7435
27
EC
- - 2.4
120807
27 - - 95.7
52475
26
EC
- - 16.8
56864
26
EC
- - 11.9
120774
22
EC
- - 80.1
88988
21
EC
- - 20.1
120634
N-
5'-phosphoribosyl
21
EC
- - 88.9
23166
20
EC
- - 1.7
86336
19
EC
- - 13.8
87677
18
EC
- - 4.7
120157
18
EC
- - 37.5
120713
18
EC
- - 76.2
74243
16
EC
- - 0.0
79557
16
EC
- - 0.0
120117
14
EC
- - 50.6
8375
13 - - 2.9
86330
12
EC
- - 20.3
86730
11
EC
- - 4.2
90254
11
EC
- - 9.4
117601
10
EC
- - 7.4
119545
10 - - 33.7
90247
10
EC
- - 1.9
33820
10
EC
- - 16.3
116267
9
EC
- - 8.0
2263
8
EC
- - 2.1
92735
8
EC
- - 8.1
24553
8
EC
- - 1.8
120537
N-
5'-phosphoribosyl
8
EC
- - 37.6
40492
7 - - 11.9
64323
6
EC
- - 12.1
104382
5 - - 9.5
120517
5
EC
- - 11.2
86796
5
EC
- - 1.0
39323
4 - - 0.0
42266
4
EC
- - 14.2
99066
4
EC
- - 0.0
119650
4 - - 0.0
83484
4
EC
- - 0.0
42384
4 - - 0.0
76047
N-
5'-phosphoribosyl
4
EC
- - 0.0
120877
N-
5'-phosphoribosyl
3
EC
- - 46.2
80772
3
EC
- - 5.2
47232
3
EC
- - 10.5
120856
3
EC
- - 41.1
74801
3
EC
- - 9.5
48674
2
EC
- - 0.0
51924
2
EC
- - 3.4
120491
N-
5'-phosphoribosyl
2
EC
- - 33.9
119519
2
EC
- - 23.2
92272
2
EC
- - 2.0
16785
2
EC
- - 0.3
97590
2
EC
- - 2.9
79089
2 - - 6.4
120917
2 - - 9.4
119478
2
EC
- - 30.0
75400
2
EC
- - 0.0
120490
2
EC
- - 34.7
64355
2
EC
- - 6.0
61478
2 - - 10.0
2033
1 - - 0.0
74251
1
EC
- - 0.0
113619
N-
5'-phosphoribosyl
1
EC
- - 0.0
120848
1
EC
- - 0.0
80118
1
EC
- - 0.0
78558
N-
5'-phosphoribosyl
1
EC
- - 0.0
84258
N-
5'-phosphoribosyl
1
EC
- - 0.0
75430
1 - - 0.0
63233
1 - - 0.0
62135
1 - - 0.0
113822
1
EC
- - 0.0
106775
1
EC
- - 0.0
88999
1 - - 0.0
88538
1
EC
- - 0.0
95730
1 - - 0.0
121015
1 - - 0.0
120519
1 - - 0.0
6002
1 - - 0.0
69248
1-
5-phosphoribosyl 5-phosphoribosylamino
1
EC
- - 0.0
3156
1 - - 0.0
36232
1 - - 0.0
113338
1
EC
- - 0.0
91961
1
EC
- - 0.0
90252
1 - - 0.0
90977
1
EC
- - 0.0
89490
N-
5'-phosphoribosyl
1
EC
- - 0.0
59950
1 - - 0.0