CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family | 3-keto-5-aminohexanoate cleavage enzyme |
Enzyme Information
| 2.3.1.247 |
3-keto-5-aminohexanoate cleavage enzyme.
based on mapping to UniProt B0VHH0
(5S)-5-amino-3-oxohexanoate + acetyl-CoA = L-3-aminobutanoyl-CoA + acetoacetate.
-!- The enzyme, isolated from the bacteria Fusobacterium nucleatum and Cloacimonas acidaminovorans, is involved in the anaerobic fermentation of lysine.
|
UniProtKB Entries (1)
| B0VHH0 |
KCE_CLOAI
Candidatus Cloacimonas acidaminovorans str. Evry
3-keto-5-aminohexanoate cleavage enzyme
|
PDB Structure
| PDB | 2Y7D |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
3-Keto-5-Aminohexanoate Cleavage Enzyme: A Common Fold for an Uncommon Claisen-Type Condensation.
J.Biol.Chem.
|