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CATH Superfamily 1.10.1040.10

N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
Glycerol-3-phosphate dehydrogenase [NAD
P
1269
3D
 3k96B02 - 93.3
2
6-phosphogluconate dehydrogenase, decarboxylating
1180
3D
 5uq9H02 - 94.5
3
Ketol-acid reductoisomerase, mitochondrial
758 - - 70.6
4
Glycerol-3-phosphate dehydrogenase [NAD
+
680
3D
 4fgwB02 - 94.9
5
Ketol-acid reductoisomerase, mitochondrial
589 - - 76.2
6
3-hydroxyisobutyrate dehydrogenase
449
3D
 2i9pD02 - 97.5
7
Ketol-acid reductoisomerase
NADP(+
387
3D
 3ulkB02 - 58.4
8
2-hydroxy-3-oxopropionate reductase
346 - - 41.7
9
Mannitol-1-phosphate 5-dehydrogenase
320
3D
 3h2zA02 - 84.3
10
3-hydroxybutyryl-CoA dehydrogenase
308 - - 59.9
11
putative oxidoreductase GLYR1 isoform X1
254
3D
 2uyyD02 - 65.2
15
Ketol-acid reductoisomerase
174
3D
 3fr8B02 - 75.4
12
Glycerol-3-phosphate dehydrogenase [NAD
+
171 - - 68.0
14
2-dehydropantoate 2-reductase
167
3D
 2ofpB02 - 75.2
13
Ketol-acid reductoisomerase, mitochondrial
163 - - 82.2
19
3-hydroxybutyryl-CoA dehydrogenase FadB2
161
3D
 3rqsB03 - 78.1
17
2-dehydropantoate 2-reductase
158
3D
 3i83B02 - 98.4
16
Glyoxylate/succinic semialdehyde reductase 2
150
3D
 3dojA02 - 84.6
18
Altronate oxidoreductase
146 - - 30.4
20
D-mannonate oxidoreductase, NAD-binding
127 - - 60.1
21
2-hydroxy-3-oxopropionate reductase
127 - - 19.7
23
lambda-crystallin homolog
88
3D
 3f3sB02 - 63.8
22
3-sulfolactaldehyde reductase
87 - - 26.8
26
UDP-glucose 6-dehydrogenase
74
3D
 1dliA03 - 46.9
24
Glycerol-3-phosphate dehydrogenase
74 - - 41.2
25
Glycerol-3-phosphate dehydrogenase [NAD
P
73 - - 63.4
27
L-carnitine dehydrogenase
66 - - 57.7
28
Mannitol 2-dehydrogenase
47 - - 70.3
29
6-phosphogluconate dehydrogenase
Decarboxylating
42 - - 27.1
30
Ketol-acid reductoisomerase
NADP(+
32 - - 18.4
32
6-phosphogluconate dehydrogenase, decarboxylating
28
3D
 1pgjB02 - 99.0
31
Glycerol-3-phosphate dehydrogenase
NAD(P +
26 - - 81.5
33
PAM1p protein
24 - - 77.0
34
Mannitol-1-phosphate 5-dehydrogenase
24
3D
 5jnmA02 - 2.7
35
2-dehydropantoate 2-reductase
20 - - 20.4
36
2-dehydropantoate 2-reductase
20 - - 2.8
38
Probable 2-dehydropantoate 2-reductase
18 - - 71.7
37
Glycerol-3-phosphate dehydrogenase [NAD
P
18 - - 22.0
39
Blast:Putative oxidoreductase GLYR1 homolog
17 - - 21.0
59
2-dehydropantoate 2-reductase
16
3D
 3g17H02 - 13.7
40
6-phosphogluconate dehydrogenase, decarboxylating
16 - - 76.7
41
2-dehydropantoate 2-reductase
16 - - 10.6
43
2-dehydropantoate 2-reductase
15
3D
 3egoB02 - 45.1
84
Glycerol-3-phosphate dehydrogenase [NAD
+
15
3D
 6e90D02 - 38.5
42
Mannitol-1-phosphate 5-dehydrogenase
15 - - 7.3
46
Ketose-bisphosphate aldolase class-II family protein
13 - - 17.5
44
Putative 3-hydroxyisobutyrate dehydrogenase
13 - - 15.2
45
Ketose-bisphosphate aldolase class-II family protein
13 - - 11.2
48
Putative 2-hydroxy-3-oxopropionate reductase
11 - - 27.5
47
2-dehydropantoate 2-reductase
11 - - 72.7
49
Related to 2-dehydropantoate 2-reductase
10 - - 53.0
51
Glycerol-3-phosphate dehydrogenase
NAD(+
9 - - 15.9
50
Probable 3-hydroxyisobutyrate dehydrogenase-like 1, mitochondrial
9 - - 18.6
52
Mitochondrial translational activator
9 - - 0.0
107
2-dehydropantoate 2-reductase
8
3D
 5hwsD02 - 41.5
53
3-hydroxyacyl-CoA dehydrogenase
8 - - 11.4
55
2-dehydropantoate 2-reductase
8
3D
 4ol9A02 - 0.0
95
Probable 2-dehydropantoate 2-reductase
8 - - 0.0
80
2-hydroxymethylglutarate dehydrogenase
7
3D
 3ckyD02 - 0.9
56
3-hydroxyisobutyrate dehydrogenase a
7 - - 69.1
54
Altronate oxidoreductase
7 - - 12.3
58
Glycerol-3-phosphate dehydrogenase [NAD
P
6 - - 14.6
61
3-hydroxyacyl-CoA dehydrogenase
6 - - 19.1
57
2-dehydropantoate 2-reductase
6 - - 79.9
60
2-dehydropantoate 2-reductase
6 - - 14.1
66
3-hydroxyisobutyrate dehydrogenase
5 - - 34.4
62
Glycerol-3-phosphate dehydrogenase [NAD
+
5 - - 3.0
64
2-dehydropantoate 2-reductase
5 - - 1.0
67
2-dehydropantoate 2-reductase
5 - - 54.8
65
Uncharacterized protein
5 - - 5.5
63
D-mannonate oxidoreductase
5 - - 0.0
71
ApbA-domain-containing protein
4 - - 0.9
76
2-dehydropantoate 2-reductase
4 - - 7.3
74
Altronate oxidoreductase
4 - - 0.0
68
ApbA-domain-containing protein
4 - - 0.8
77
AGAP012912-PA
4 - - 36.3
69
2-dehydropantoate 2-reductase
4 - - 9.3
72
2-hydroxy-3-oxopropionate reductase
4 - - 2.6
73
Putative 3-hydroxyisobutyrate dehydrogenase
4 - - 0.9
70
3-hydroxyisobutyrate dehydrogenase, mitochondrial, putative
4 - - 11.6
75
2-dehydropantoate 2-reductase
4 - - 4.0
78
YALI0D20438p
3 - - 0.0
82
Uncharacterized protein
3 - - 17.4
79
NAD binding domain of 6-phosphogluconate dehydrogenase/NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase, putative
3 - - 8.3
83
Chromosome 1, whole genome shotgun sequence
3 - - 58.9
81
2-dehydropantoate 2-reductase
3 - - 10.4
101
Oxidoreductase subunit
2 - - 0.0
96
Glyoxylate reductase 1
2 - - 2.9
98
Glycerol-3-phosphate dehydrogenase [NAD
+
2 - - 0.0
87
Uncharacterized protein
2 - - 0.0
85
Putative 2-dehydropantoate 2-reductase
2 - - 34.6
102
Ketose-bisphosphate aldolase class-II family protein
2 - - 7.9
89
Uncharacterized protein
2 - - 0.9
91
Uncharacterized protein
2 - - 0.0
92
2-dehydropantoate 2-reductase family protein, putative
2 - - 0.0
105
Uncharacterized protein
2 - - 0.0
100
Uncharacterized protein
2 - - 0.0
94
Putative 2-dehydropantoate 2-reductase
2 - - 0.0
99
Ketol-acid reductoisomerase chloroplastic
2 - - 35.3
90
2-dehydropantoate 2-reductase
2 - - 0.9
93
2-dehydropantoate 2-reductase
2 - - 0.0
104
AaceriAGL109Wp
2 - - 11.6
103
Oxidoreductase subunit
2 - - 0.0
97
Uncharacterized protein
2 - - 0.0
106
Uncharacterized protein
2 - - 0.0
86
2-dehydropantoate 2-reductase
2 - - 0.0
88
Ketopantoate reductase PanE/ApbA-domain-containing protein
2 - - 0.0
119
Uncharacterized protein
1 - - 0.0
116
Uncharacterized protein
1 - - 0.0
110
Predicted protein
1 - - 0.0
112
Ketopantoate reductase
1 - - 0.0
108
Glycerol-3-phosphate dehydrogenase
NAD(P +
1 - - 0.0
115
Uncharacterized protein
1 - - 0.0
122
Uncharacterized protein
1 - - 0.0
125
Uncharacterized protein
1 - - 0.0
117
Predicted protein
1 - - 0.0
111
3-hydroxyisobutyrate dehydrogenase
1 - - 0.0
118
Uncharacterized protein
1 - - 0.0
124
Glycerol-3-phosphate dehydrogenase [NAD
+
1 - - 0.0
113
Uncharacterized protein
1 - - 0.0
120
Uncharacterized protein
1 - - 0.0
109
Uncharacterized protein
1 - - 0.0
126
Glycerol-3-phosphate dehydrogenase [NAD
+
1 - - 0.0
114
Uncharacterized protein
1 - - 0.0
121
Uncharacterized protein
1 - - 0.0
123
Glycerol-3-phosphate dehydrogenase [NAD
+
1 - - 0.0