1 keywords

CATH Domain 6e90D02

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.1040 N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
Homologous Superfamily 1.10.1040.10 N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2

Domain Context

CATH Clusters

Superfamily N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
Functional Family Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

Enzyme Information

1.1.1.8
Glycerol-3-phosphate dehydrogenase (NAD(+)).
based on mapping to UniProt P21695
sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH.
-!- Also acts on propane-1,2-diol phosphate and glycerone sulfate (but with a much lower affinity).

UniProtKB Entries (1)

P21695
GPDA_HUMAN
Homo sapiens
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

PDB Structure

PDB 6E90
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Human Glycerol 3-Phosphate Dehydrogenase: X-ray Crystal Structures That Guide the Interpretation of Mutagenesis Studies.
Mydy, L.S., Cristobal, J.R., Katigbak, R.D., Bauer, P., Reyes, A.C., Kamerlin, S.C.L., Richard, J.P., Gulick, A.M.
Biochemistry