CATH Superfamily 2.40.50.100

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Enzyme?	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
50219	Acetyl-coa biotin carboxyl carrier	58458	EC	3D	1a6xA00	-	98.3
50346	DNA-directed RNA polymerase subunit beta	34547	EC	3D	2aukA01	-	96.6
50450	ABC transporter ATP-binding protein	31268	EC	3D	3gd7A02	-	87.2
50336	Pyruvate dehydrogenase E2 component	24349	EC	3D	1qjoA00	-	96.4
50276	Methylcrotonoyl-CoA carboxylase subunit alpha	19667	EC	3D	2ejmA01	-	99.7
50288	50S ribosomal protein L27	18202		3D	1v8qA00	-	97.1
50506	Molybdenum import ATP-binding protein ModC	15032	EC	3D	1b9mA02	-	94.7
50279	Efflux transporter, RND family, MFP subunit	14592	EC	3D	2f1mA02	-	98.0
49437	RNA polymerase beta subunit	14535	EC	3D	4jk1C05	-	98.6
49992	Glycine cleavage system H protein	10326	EC	3D	2edgA00	-	86.1
50113	Pyruvate dehydrogenase protein X component	9840	EC	3D	1fycA00	-	86.0
50344	DNA-directed RNA polymerase subunit beta/beta	9116	EC	3D	2lmcB00	-	96.0
50323	Chloroplast cytochrome f	5192		3D	1ctmA02	-	96.6
50221	RNA polymerase beta subunit	5045	EC	3D	1i6vC05	-	99.3
49477	DNA-directed RNA polymerase subunit beta	4754	EC	3D	2aukA02	-	92.6
49827	RNA polymerase beta subunit	4344	EC		-	-	99.3
48384	Cation efflux system protein CusB	4154		3D	3h94A03	-	50.4
49757	RNA polymerase beta subunit	3938	EC		-	-	99.7
49717	p-hydroxybenzoic acid efflux subunit AaeA	3052			-	-	80.6
49808	RNA polymerase beta subunit	3033	EC		-	-	99.7
25964	ABC transporter family protein	2692	EC		-	-	8.4
50251	V-type ATPase subunit A	2192	EC		-	-	91.1
50107	Oxaloacetate decarboxylase, alpha subunit	2103	EC	3D	1dczA00	-	99.2
4791	RNA polymerase beta subunit	2001	EC		-	-	86.0
50109	DNA-directed RNA polymerase subunit beta	1999	EC		-	-	88.9
50292	Acetyl-CoA carboxylase, isoform A	1706	EC	3D	2dn8A01	-	82.3
49706	DNA-directed RNA polymerase subunit beta	1457	EC		-	-	98.9
50255	Secretion protein, HlyD family	1310			-	-	93.7
50231	V-type ATP synthase alpha chain	1073	EC	3D	3gqbA03	-	100.0
49584	DNA-directed RNA polymerase subunit beta	1049	EC		-	-	51.7
50216	Na +	1003	EC		-	-	89.3
50297	DNA-directed RNA polymerase subunit beta	790	EC		-	-	95.8
49801	DNA-directed RNA polymerase	766	EC		-	-	92.5
50430	RNA polymerase beta'' subunit	732	EC	3D	1iw7D10	-	81.4
15333	V-type ATP synthase alpha chain	683	EC		-	-	15.7
49816	Pyruvate carboxylase, mitochondrial	573	EC	3D	3bg3A05	-	97.0
49761	DNA-directed RNA polymerase beta subunit	563	EC		-	-	94.0
49062	DNA-directed RNA polymerase homolog	552	EC		-	-	83.5
49448	DNA-directed RNA polymerase subunit beta/beta	550	EC		-	-	92.8
49929	DNA-directed RNA polymerase subunit beta'	502	EC		-	-	59.8
4557	DNA-directed RNA polymerase subunit beta'	490	EC		-	-	40.1
49120	Dihydrolipoamide branched chain transacylase E2	439	EC	3D	1k8mA00	-	89.0
50111	RNA polymerase beta subunit	378	EC		-	-	91.9
48634	Acetyl-/propionyl-coenzyme A carboxylase alpha chain	301	EC		-	-	40.5
23075	Sulfate/thiosulfate import ATP-binding protein CysA	269	EC		-	-	20.7
2813	RNA polymerase beta subunit	236	EC		-	-	29.4
49789	V-type ATP synthase alpha chain	230	EC		-	-	85.3
50141	Propionyl-CoA carboxylase alpha chain, mitochondrial	219	EC		-	-	85.1
50211	RNA polymerase beta'' subunit	183	EC		-	-	98.3
11819	RnfC Barrel sandwich hybrid domain protein	178	EC		-	-	24.6
50061	Branched-chain alpha-keto acid dehydrogenasesubunit E2	176	EC		-	-	30.2
32764	Pyruvate dehydrogenase complex E2, dihydrolipoamide acetyltransferase	163			-	-	79.2
49831	V-type ATP synthase alpha chain	159	EC		-	-	87.1
50443	Marine sediment metagenome DNA, contig: S03H2_S03155	152	EC		-	-	96.7
10792	V-type ATP synthase alpha chain	125	EC		-	-	1.7
27246	Multiple sugar-binding transporter ATP-binding protein	121	EC		-	-	0.0
9984	Pyruvate carboxylase	115	EC		-	-	72.2
50248	Cytochrome f	111		3D	1ci3M02	-	97.9
50197	Alkaline protease secretion protein AprE	98			-	-	41.9
50448	sn-glycerol-3-phosphate import ATP-binding protein UgpC	98	EC		-	-	51.9
50287	Cytochrome f, chloroplastic	95		3D	1cfmA02	-	98.3
49817	V-type ATP synthase alpha chain	83	EC	3D	1vdzA02	-	89.3
9919	Pyruvate carboxylase Eurofung	82	EC		-	-	29.9
49951	DNA-directed RNA polymerase subunit beta	81	EC		-	-	75.7
35606	Acetyltransferase component of pyruvate dehydrogenase complex	76	EC		-	-	13.6
36493	Multidrug resistance efflux pump	72			-	-	58.9
49158	DNA-directed RNA polymerase subunit beta	70	EC		-	-	50.0
49784	V-type ATP synthase alpha chain	65	EC		-	-	59.8
4781	DNA-directed RNA polymerase subunit beta	64	EC		-	-	11.6
48259	DNA-directed RNA polymerase subunit beta'	63	EC		-	-	42.6
16340	DNA-directed RNA polymerase subunit beta'	61	EC		-	-	11.2
49606	Dihydrolipoyllysine-residue succinyltransferase component of	61	EC		-	-	40.7
50486	DNA-directed RNA polymerase subunit beta	61	EC		-	-	96.7
49209	Biotin/lipoyl attachment domain-containing protein	57			-	-	66.4
14024	V-type ATP synthase alpha chain	54	EC		-	-	5.2
19697	Probable Co/Zn/Cd efflux system membrane fusion protein	53			-	-	16.1
26051	RND efflux membrane fusion protein	53			-	-	6.0
19502	V-type ATP synthase alpha chain	53	EC		-	-	9.9
50403	Alginate biosynthesis protein Alg44	53			-	-	58.5
16387	DNA-directed RNA polymerase subunit beta'	50	EC		-	-	8.2
50191	Multidrug resistance protein, putative	49			-	-	59.8
49593	V-type ATP synthase subunit A	46	EC		-	-	65.4
10755	Acetyl-CoA carboxylase, mitochondrial	45	EC		-	-	0.0
50419	Homolog to phosphatidylserine decarboxylase	43	EC		-	-	94.5
9661	Pyruvate carboxylase 1	42	EC		-	-	0.0
26664	Efflux pump periplasmic linker BepD	41			-	-	16.9
27191	ABC transporter ATP-binding protein	39	EC		-	-	0.0
9711	Pyruvate carboxylase 2	38	EC		-	-	4.5
28345	Efflux transporter, RND family, MFP subunit	36			-	-	0.0
14039	V-type ATP synthase alpha chain	36	EC		-	-	30.5
19395	V-type ATP synthase alpha chain 1	36	EC		-	-	0.0
48512	RNA polymerase II subunit A C-terminal domain phosphatase	33	EC		-	-	41.9
11783	V-type ATP synthase alpha chain	32	EC		-	-	1.7
50145	Hemolysin secretion protein D, plasmid	28			-	-	57.4
49600	DNA-directed RNA polymerase	25	EC		-	-	88.2
15354	Glutaconyl-CoA decarboxylase subunit gamma	22	EC		-	-	39.0
10840	Carbamoyl-phosphate synthase subunit L	22	EC		-	-	3.5
48493	DNA-directed RNA polymerase subunit beta	22		3D	1iw7M05	-	13.6
50420	DNA-directed RNA polymerase subunit beta'	21	EC		-	-	74.7
10758	DNA-directed RNA polymerase Beta	21	EC		-	-	19.4
50204	DNA-directed RNA polymerase subunit beta	20	EC		-	-	82.7
30442	ABC transporter related	16	EC		-	-	0.0
49148	Urea amidolyase	16	EC		-	-	0.0
29460	Electron transport complex subunit C	15			-	-	0.0
18467	V-type ATP synthase alpha chain	15	EC		-	-	4.8
25956	Fe 3+	14	EC		-	-	20.3
7400	DNA-directed RNA polymerase beta chain	14	EC		-	-	5.5
12863	Likely pyruate carboxylase	14	EC		-	-	39.7
48385	V-type ATP synthase alpha chain	13	EC		-	-	32.9
29687	Trehalose/maltose import ATP-binding protein MalK	11	EC		-	-	2.1
9668	V-type ATP synthase alpha chain	11	EC		-	-	0.0
4409	Biotin/lipoyl attachment domain-containing protein	10	EC		-	-	9.6
9670	DNA-directed RNA polymerase subunit beta'	10	EC		-	-	0.0
25984	Multiple sugar-binding transport ATP-binding protein MsmK	9			-	-	0.0
6033	DNA-directed RNA polymerase subunit beta'	8	EC		-	-	4.3
49725	Cytochrome f	8			-	-	62.9
35599	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex	7	EC		-	-	6.9
2699	DNA-directed RNA polymerase subunit beta'	7	EC		-	-	2.4
23102	DNA-directed RNA polymerase subunit beta'	6	EC		-	-	20.1
49466	V-type ATP synthase alpha chain	6	EC		-	-	29.2
50016	V-type ATP synthase alpha chain	6	EC		-	-	45.1
49983	DNA-directed RNA polymerase subunit beta	6	EC		-	-	41.9
3540	Fcp1, isoform A	6	EC		-	-	17.1
11251	Pyruvate carboxylase	6	EC		-	-	5.2
34286	Secretion protein, HlyD family	5			-	-	6.3
29393	Alkaline protease secretion protein AprE	5			-	-	18.2
48972	Alginate biosynthesis protein Alg44	5			-	-	0.0
49037	V-type ATP synthase alpha chain	5	EC		-	-	22.2
49753	DNA-directed RNA polymerase delta = beta''	5	EC		-	-	30.3
50293	DNA-directed RNA polymerase subunit beta''	5	EC		-	-	5.5
12496	V-type ATP synthase alpha chain	5	EC		-	-	6.9
2400	DNA-directed RNA polymerase subunit beta'	4	EC		-	-	4.8
23966	Lactose transport ATP-binding protein LacK	4			-	-	0.0
50073	V-type ATP synthase alpha chain	4	EC		-	-	44.6
19584	p-hydroxybenzoic acid efflux pump subunit AaeA	4			-	-	0.0
50098	HlyD family secretion protein	4			-	-	42.5
27202	Cytochrome f	4			-	-	0.0
3478	DNA-directed RNA polymerase subunit beta'	4	EC		-	-	7.3
50444	UPF0194 membrane protein RB0873	4			-	-	0.0
50148	Cytochrome f	3			-	-	74.8
2490	RNA polymerase subunit B	3	EC		-	-	6.5
17212	p-hydroxybenzoic acid efflux pump subunit AaeA	3			-	-	30.9
3751	DNA-directed RNA polymerase subunit beta'	3	EC		-	-	21.2
50178	Multidrug resistance protein MdtN	3			-	-	0.0
48416	DNA-directed RNA polymerase subunit beta'	2	EC		-	-	31.7
7130	Acetoin cleaving system dihydrolipoyllysine-residue acetyltransferase	2			-	-	8.9
2259	DNA-directed RNA polymerase subunit beta'	2	EC		-	-	4.2
9688	DNA-directed RNA polymerase subunit beta	2	EC		-	-	0.0
27187	Cytochrome f	2			-	-	2.1
49242	V-type ATP synthase alpha chain	2	EC		-	-	34.5
19636	V-type ATP synthase alpha chain	2	EC		-	-	5.0
6663	Biotin carboxyl carrier protein	2			-	-	0.0
29511	Multidrug resistance protein A	1			-	-	0.0
28336	Apocytochrome f	1			-	-	0.0
49289	Efflux transporter, RND family, MFP subunit	1			-	-	0.0
50440	DNA-directed RNA polymerase subunit beta''	1			-	-	0.0
6038	Pyruvate carboxylase subunit B	1	EC		-	-	0.0
6494	Cytochrome f	1			-	-	0.0
3154	DNA-directed RNA polymerase subunit beta'	1	EC		-	-	0.0
23961	DNA-directed RNA polymerase subunit beta'	1		3D	2aujD03	-	0.0
49264	V-type ATP synthase alpha chain	1	EC		-	-	0.0
50421	DNA-directed RNA polymerase subunit beta'	1	EC		-	-	0.0
49189	Cytochrome b6-f complex subunit	1			-	-	0.0
49695	DNA-directed RNA polymerase	1			-	-	0.0
42886	Putative hlyD-like secretion protein	1			-	-	0.0
49233	DNA-directed RNA polymerase subunit beta	1	EC		-	-	0.0
33713	Uncharacterized ABC transporter ATP-binding protein y4oS	1			-	-	0.0
6120	Multidrug resistance protein A	1			-	-
25351	Efflux transporter, RND family, MFP subunit	1			-	-	0.0
27190	Cytochrome f	1			-	-	0.0
24928	Sulfate/thiosulfate import ATP-binding protein CysA	1			-	-	0.0
2263	DNA-directed RNA polymerase subunit beta	1	EC		-	-	0.0
3607	DNA-directed RNA polymerase subunit beta	1	EC		-	-	0.0
10778	Pyruvate carboxylase subunit B	1	EC		-	-	0.0