CATH Classification
Domain Context
CATH Clusters
Superfamily | 2.40.50.100 |
Functional Family | ABC transporter ATP-binding protein |
Enzyme Information
3.6.3.49 |
Channel-conductance-controlling ATPase.
based on mapping to UniProt P13569
ATP + H(2)O = ADP + phosphate.
-!- An animal enzyme that is active in forming a chloride channel, the absence of which brings about cystic fibrosis. -!- It is also involved in the functioning of other transmembrane channels.
|
3.6.3.19 |
Maltose-transporting ATPase.
based on mapping to UniProt P68187
ATP + H(2)O + maltose(Out) = ADP + phosphate + maltose(In).
-!- Comprises bacterial enzymes that import maltose and maltose oligosaccharides.
|
UniProtKB Entries (2)
P68187 |
MALK_ECOLI
Escherichia coli K-12
Maltose/maltodextrin import ATP-binding protein MalK
|
P13569 |
CFTR_HUMAN
Homo sapiens
Cystic fibrosis transmembrane conductance regulator
|
PDB Structure
PDB | 3GD7 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal structure of human NBD2 complexed with N6-Phenylethyl-ATP (P-ATP)
To be Published
|