1 keywords

CATH Domain 1a6xA00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.40 Beta Barrel
Topology 2.40.50 OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous Superfamily 2.40.50.100 RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain

Domain Context

CATH Clusters

Superfamily 2.40.50.100
Functional Family Acetyl-coa biotin carboxyl carrier

Enzyme Information

6.4.1.2
Acetyl-CoA carboxylase.
based on mapping to UniProt P0ABD8
ATP + acetyl-CoA + HCO(3)(-) = ADP + phosphate + malonyl-CoA.
-!- Also catalyzes transcarboxylation; the plant enzyme also carboxylates propanoyl-CoA and butanoyl-CoA.

UniProtKB Entries (1)

P0ABD8
BCCP_ECOLI
Escherichia coli K-12
Biotin carboxyl carrier protein of acetyl-CoA carboxylase

PDB Structure

PDB 1A6X
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Structure of the carboxy-terminal fragment of the apo-biotin carboxyl carrier subunit of Escherichia coli acetyl-CoA carboxylase.
Yao, X., Wei, D., Soden Jr., C., Summers, M.F., Beckett, D.
Biochemistry