The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleoside Triphosphate Pyrophosphohydrolase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
1269
3D
5yguB00 - 78.8
3
459
3D
2qkmH02 - 92.2
2
438
3D
3mcfB00 - 95.1
4
378
3D
5isyC02 - 80.9
16
371
3D
5nwhB00 - 91.2
5
351 - - 76.3
6
328
3D
1vhzB01 - 85.1
8
290
3D
3q2tB01 - 75.8
9
284
3D
2vnqB00 - 90.8
7
281 - - 18.9
10
253
3D
3o6zB00 - 72.5
14
216
3D
3a6vB00 - 93.1
11
209
3D
1viqC00 - 72.6
12
204
3D
2pnyA00 - 91.9
17
201
3D
3shdL00 - 0.8
13
190 - - 19.3
15
185 - - 87.2
18
159
3D
3j7ye00 - 95.1
19
144
3D
3dupB01 - 93.1
20
140 - - 91.9
21
126
3D
1qvjA02 - 90.1
22
122 - - 80.0
23
118 - - 77.6
25
104 - - 80.3
24
104 - - 93.5
26
103
3D
1x51A01 - 97.1
27
100
3D
3h95A01 - 87.8
43
99
3D
5ws7B00 - 55.8
34
99
3D
6dbzB00 - 92.5
28
89 - - 83.5
29
85 - - 24.6
30
84 - - 78.8
32
81
3D
1jknA00 - 80.6
31
80 - - 72.6
33
77 - - 84.6
37
77
3D
4ijxB00 - 80.0
35
74
3D
3q91D00 - 92.6
38
71
3D
6d0lB00 - 55.7
36
66 - - 93.3
41
66
3D
2o5wD00 - 21.5
39
58 - - 3.4
40
58 - - 86.7
45
50
3D
4kg4B00 - 88.5
42
50 - - 77.0
55
47
3D
6co2B00 - 72.2
44
44 - - 70.9
46
42 - - 62.9
48
39 - - 55.1
49
39 - - 86.2
47
39 - - 85.8
50
37 - - 74.4
51
36 - - 84.4
52
32 - - 9.2
53
31 - - 82.8
64
30
3D
2gt4C00 - 13.9
54
30 - - 7.2
56
28 - - 54.7
57
27 - - 19.7
58
26 - - 4.1
60
26
3D
4kyxB00 - 93.7
59
25 - - 32.8
61
23 - - 40.7
62
23 - - 64.9
101
21
3D
2a8tB00 - 82.6
65
21 - - 10.5
63
21 - - 0.0
76
20
3D
5cfjA00 - 14.5
66
20 - - 71.1
68
18 - - 75.1
69
18 - - 9.0
67
18 - - 44.0
71
17 - - 9.8
70
17 - - 8.7
74
16 - - 80.9
72
16 - - 42.6
73
16 - - 0.6
80
15
3D
4hvyA00 - 69.7
97
15
3D
1mr2A00 - 0.0
75
15 - - 31.2
78
14 - - 19.8
77
14 - - 7.6
79
14 - - 73.2
81
14 - - 70.6
85
13 - - 20.6
84
13 - - 13.0
82
13 - - 1.4
83
13 - - 0.0
86
13 - - 80.2
87
nucleoside diphosphate linked moiety X
12 - - 77.9
89
12 - - 0.0
90
12 - - 0.8
88
12 - - 88.0
96
11 - - 86.4
91
11 - - 8.6
92
11 - - 1.6
94
11 - - 4.1
93
11 - - 11.3
95
11 - - 43.7
98
10 - - 14.3
100
10 - - 0.8
99
10 - - 13.5
133
9
3D
1vcdB01 - 1.0
107
8 - - 4.9
110
8 - - 81.9
108
8 - - 13.1
102
8 - - 0.5
105
8 - - 1.4
109
8 - - 4.6
104
8 - - 16.2
103
8 - - 11.2
106
8 - - 20.4
116
7 - - 0.0
112
7 - - 79.8
115
7 - - 13.9
117
7 - - 86.6
111
7 - - 89.9
113
7 - - 74.5
114
7 - - 9.4
119
6 - - 3.8
154
6
3D
2o5fB00 - 76.6
122
6 - - 13.9
125
6 - - 83.8
118
6 - - 0.6
124
6 - - 0.0
120
6 - - 0.0
121
6 - - 19.1
123
6 - - 5.8
127
MutT/nudix family protein
5 - - 17.7
136
5 - - 7.3
170
5
3D
2qjoC02 - 0.0
128
5 - - 13.9
130
5 - - 14.5
299
5
3D
3gz8D01 - 0.0
132
5 - - 7.3
129
5 - - 15.6
135
5 - - 2.5
126
5 - - 19.0
131
5 - - 0.0
134
5 - - 12.8
144
4 - - 5.9
151
4 - - 73.6
138
4 - - 32.5
137
4 - - 32.4
142
MUTT/NUDIX family protein
4 - - 8.3
140
4 - - 77.4
147
4 - - 15.5
149
4 - - 0.0
139
4 - - 18.6
145
4 - - 9.3
150
4 - - 79.3
143
4 - - 11.2
148
4 - - 2.1
141
4 - - 16.4
146
4 - - 6.5
153
3 - - 34.8
160
3 - - 8.3
155
3 - - 7.5
163
3 - - 67.0
158
3 - - 0.7
165
3 - - 3.7
156
3 - - 4.5
152
3 - - 39.8
161
3 - - 0.0
159
3 - - 11.7
162
3 - - 0.0
157
3 - - 13.6
166
3 - - 51.2
164
3 - - 0.0
211
2 - - 0.0
218
2 - - 28.0
193
MutT/nudix family protein
2 - - 0.0
180
2 - - 42.5
189
2 - - 0.0
177
nucleoside diphosphate-linked moiety X
2 - - 13.2
205
2 - - 0.0
191
2 - - 0.0
187
2 - - 0.0
212
2 - - 0.0
182
2 - - 10.0
207
2 - - 1.1
167
2 - - 0.0
175
2 - - 11.3
198
2 - - 6.9
202
2 - - 6.9
184
2 - - 0.0
181
2 - - 0.0
214
2 - - 3.3
217
2 - - 0.0
186
2 - - 0.0
209
2 - - 0.0
210
2 - - 0.0
173
basic FGF2
2 - - 0.0
219
2 - - 39.8
196
2 - - 9.5
206
2 - - 0.0
194
2 - - 6.6
220
2 - - 36.7
168
AFU_orthologue AFUA_2G14290
2 - - 0.0
178
2 - - 25.4
213
2 - - 0.0
171
2 - - 5.1
200
2 - - 12.3
197
2 - - 2.3
176
2 - - 27.7
192
2 - - 2.6
215
2 - - 0.0
208
2 - - 32.9
199
2 - - 2.0
195
2 - - 0.0
201
2 - - 0.0
174
2 - - 21.9
188
2 - - 0.0
183
2 - - 1.2
169
2 - - 7.6
190
2 - - 0.0
203
MutT/nudix family protein
2 - - 0.0
204
2 - - 0.0
172
2 - - 0.0
216
2 - - 0.0
179
2 - - 37.3
185
2 - - 0.0
236
1 - - 0.0
285
1 - - 0.0
234
1 - - 0.0
288
1 - - 0.0
246
1 - - 0.0
221
1 - - 0.0
260
1 - - 0.0
301
1 - - 0.0
272
1 - - 0.0
287
1 - - 0.0
294
1 - - 0.0
262
1 - - 0.0
227
1 - - 0.0
264
1 - - 0.0
255
1 - - 0.0
232
1 - - 0.0
225
1 - - 0.0
274
1 - - 0.0
250
1 - - 0.0
303
1 - - 0.0
278
1 - - 0.0
257
1 - - 0.0
276
1 - - 0.0
259
1 - - 0.0
249
1 - - 0.0
240
1 - - 0.0
230
1 - - 0.0
229
1 - - 0.0
222
1 - - 0.0
305
1 - - 0.0
239
1 - - 0.0
281
1 - - 0.0
269
1 - - 0.0
284
1 - - 0.0
247
1 - - 0.0
289
1 - - 0.0
297
1 - - 0.0
290
1 - - 0.0
252
1 - - 0.0
283
1 - - 0.0
271
1 - - 0.0
242
1 - - 0.0
226
1 - - 0.0
244
1 - - 0.0
295
1 - - 0.0
237
1 - - 0.0
300
1 - - 0.0
286
1 - - 0.0
254
1 - - 0.0
235
1 - - 0.0
265
1 - - 0.0
296
1 - - 0.0
275
1 - - 0.0
224
1 - - 0.0
251
1 - - 0.0
279
1 - - 0.0
256
1 - - 0.0
263
nucleoside diphosphate linked moiety X
1 - - 0.0
293
1 - - 0.0
245
1 - - 0.0
267
1 - - 0.0
233
1 - - 0.0
292
1 - - 0.0
291
1 - - 0.0
241
1 - - 0.0
280
1 - - 0.0
273
1 - - 0.0
270
1 - - 0.0
266
1 - - 0.0
302
1 - - 0.0
298
1 - - 0.0
243
1 - - 0.0
231
1 - - 0.0
261
1 - - 0.0
228
1 - - 0.0
268
1 - - 0.0
223
1 - - 0.0
282
1 - - 0.0
238
1 - - 0.0
253
1 - - 0.0
277
1 - - 0.0
304
1 - - 0.0
258
1 - - 0.0
248
1 - - 0.0