The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
2-enoyl-CoA Hydratase; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
2200
3D
6h23N00 - 96.2
2
930
3D
4u0gU00 - 93.6
3
820
3D
4i42L01 - 86.0
4
597
3D
4q0gC02 - 86.1
5
588
3D
5cteC01 - 88.2
7
509
3D
4q0gC01 - 79.5
6
503 - - 75.9
9
450
3D
5jbxC01 - 95.0
8
446
3D
2f9yA00 - 69.1
10
424
3D
5cteC03 - 86.0
16
375
3D
2bzrF01 - 88.7
12
344
3D
2fbmC01 - 78.5
11
336 - - 98.0
13
329
3D
2f9yB00 - 44.5
17
324
3D
2bzrF02 - 85.4
14
316
3D
1y7oG00 - 73.2
15
303 - - 73.3
18
272
3D
2d3tB01 - 72.8
19
259
3D
4fjwF01 - 89.6
22
174
3D
2zqrF01 - 77.8
21
164
3D
5iklF02 - 92.6
20
162 - - 87.7
23
154 - - 93.9
24
153
3D
2vreC01 - 92.4
32
151
3D
6n97F01 - 16.8
26
143
3D
3bptA00 - 94.5
25
143
3D
2wtbA01 - 80.6
27
139 - - 88.7
28
127 - - 36.8
29
125 - - 92.0
30
123 - - 88.2
36
122
3D
2vsuF01 - 50.2
33
118
3D
3bf0D03 - 82.9
31
115 - - 83.9
34
108
3D
1sg4C01 - 93.6
35
99 - - 76.2
37
96 - - 71.7
39
93
3D
4g2rB01 - 39.9
38
89 - - 77.6
40
86 - - 80.5
48
85
3D
4zdfB00 - 89.9
42
85
3D
4f47A01 - 82.7
41
80 - - 54.5
43
77 - - 75.8
44
76
3D
1j7xA02 - 73.1
45
74 - - 29.0
53
74
3D
1n6fF05 - 75.0
46
73
3D
5iklF01 - 88.8
47
73
3D
4b3jB01 - 88.2
52
72
3D
5mgbB01 - 92.3
49
62 - - 95.8
50
61 - - 71.6
236
3,5-dihydroxyphenyl
56
3D
5kajL02 - 22.2
63
55
3D
4hnkN00 - 20.8
51
52 - - 40.5
54
47 - - 73.9
55
46 - - 86.6
56
45 - - 39.9
58
43 - - 78.1
57
43 - - 4.9
60
41
3D
4l6wB02 - 19.8
59
39 - - 2.3
67
38
3D
2f6iG00 - 24.4
75
36
3D
4jcrN00 - 43.5
61
35 - - 82.0
66
35
3D
4zu2C01 - 92.2
62
34 - - 67.3
64
33 - - 30.6
115
33
3D
5dufA00 - 1.9
213
32
3D
2hw5F01 - 36.5
65
32 - - 6.2
68
31 - - 13.9
73
31
3D
3peaF00 - 37.6
71
30
3D
4fzwD01 - 82.3
69
29 - - 11.6
84
29
3D
4u1aC01 - 81.2
70
29 - - 8.5
72
27 - - 53.2
74
AFU_orthologue AFUA_2G10650
23 - - 82.3
78
21 - - 18.2
191
21
3D
1szoL00 - 30.7
76
21 - - 32.3
77
21 - - 84.9
79
21 - - 14.3
80
20 - - 90.5
95
20
3D
3m6nC01 - 13.1
102
20
3D
4hc8B00 - 20.9
81
19 - - 83.9
82
18 - - 6.7
83
17 - - 44.8
85
16 - - 5.4
89
16 - - 93.0
91
16 - - 59.3
90
16 - - 80.5
86
16 - - 27.8
87
16 - - 71.8
97
16
3D
4jjtC00 - 23.4
88
16 - - 9.2
92
15 - - 18.0
93
15 - - 6.4
94
14 - - 48.0
96
13 - - 75.4
99
13 - - 16.3
98
13 - - 22.6
100
13 - - 0.7
101
12 - - 18.9
104
12 - - 72.0
103
12 - - 2.9
108
11 - - 2.0
105
11 - - 0.0
109
11 - - 93.5
106
11 - - 6.9
107
11 - - 14.5
110
11 - - 73.9
116
10 - - 0.0
112
10 - - 28.1
117
10 - - 5.8
111
10 - - 8.6
113
AFU_orthologue AFUA_2G14850
10 - - 88.8
120
10 - - 0.0
119
10 - - 8.7
118
10 - - 0.0
114
10 - - 0.9
136
9
3D
4rcnB04 - 37.8
124
9 - - 15.5
121
9 - - 12.0
122
9 - - 14.3
125
9 - - 0.0
123
9 - - 10.1
127
8 - - 0.0
128
8 - - 9.9
147
8
3D
4rcnB03 - 33.4
129
8 - - 24.4
130
8 - - 50.2
126
8 - - 20.8
132
7 - - 15.5
135
7 - - 0.0
131
7 - - 28.1
133
7 - - 9.3
134
7 - - 13.4
153
6
3D
4q1hB01 - 0.0
137
Endopeptidase IV
6 - - 10.1
142
6 - - 22.2
139
6 - - 14.2
145
6 - - 0.0
141
6 - - 25.2
146
6 - - 20.8
144
6 - - 14.2
138
6 - - 18.8
140
6 - - 0.0
143
6 - - 11.8
155
5 - - 1.0
154
5 - - 2.4
158
5 - - 0.6
165
5 - - 15.9
149
5 - - 77.3
168
5 - - 7.1
152
5 - - 2.2
161
5 - - 5.6
148
Endopeptidase IV
5 - - 0.0
157
PaaF-4
5 - - 9.1
164
5 - - 5.1
160
5 - - 38.5
151
5 - - 0.0
167
5 - - 73.3
163
5 - - 6.2
156
5 - - 13.4
150
5 - - 9.9
159
5 - - 10.5
162
5 - - 6.4
166
5 - - 0.0
180
4 - - 4.8
187
4 - - 13.4
170
4 - - 10.4
175
4 - - 8.6
184
4 - - 6.7
181
4 - - 1.2
178
4 - - 14.5
174
Enoyl hydrase Unsaturated acyl-CoA hydratase Crotonase
4 - - 1.3
188
4 - - 4.2
183
4 - - 1.3
179
4 - - 15.4
189
4 - - 31.8
177
4 - - 9.9
182
4 - - 11.0
186
4 - - 14.4
173
4 - - 4.3
171
4 - - 34.4
176
4 - - 83.2
169
4 - - 0.0
172
4 - - 72.9
185
4 - - 2.8
207
3 - - 5.4
198
3 - - 0.0
202
3 - - 6.6
209
3 - - 9.7
210
3 - - 8.0
341
3
3D
4izbB01 - 0.0
200
3 - - 0.9
192
3 - - 77.3
199
3 - - 4.5
195
3 - - 6.8
203
3 - - 0.0
204
3 - - 0.0
211
3 - - 71.9
193
3 - - 18.9
205
3 - - 7.1
196
3 - - 0.0
206
3 - - 5.7
194
3 - - 5.1
197
3 - - 0.0
208
3 - - 12.8
201
3 - - 5.5
190
3 - - 55.7
246
2 - - 16.2
262
2 - - 1.1
212
2 - - 12.2
232
2 - - 0.0
225
2 - - 0.0
257
2 - - 0.0
229
2 - - 4.0
222
2 - - 3.7
217
2 - - 45.4
247
2 - - 42.9
252
2 - - 4.5
242
2 - - 0.0
254
2 - - 0.4
224
2 - - 0.0
263
2 - - 0.0
267
2 - - 36.5
233
2 - - 9.7
243
2 - - 0.0
228
2 - - 7.1
268
2 - - 39.8
238
2 - - 2.9
253
2 - - 5.5
258
2 - - 0.0
248
2 - - 9.6
218
2 - - 44.3
234
2 - - 0.0
221
2 - - 0.0
260
2 - - 31.4
227
2 - - 0.0
264
2 - - 7.6
255
2 - - 8.6
250
2 - - 6.9
259
2 - - 0.0
249
2 - - 6.7
240
2 - - 8.4
230
2 - - 0.0
214
2 - - 30.6
239
2 - - 1.6
269
2 - - 25.2
219
2 - - 42.0
220
2 - - 51.4
226
2 - - 0.0
244
2 - - 0.0
237
2 - - 0.0
235
2 - - 0.7
265
2 - - 0.0
251
2 - - 0.0
256
2 - - 0.0
215
2 - - 45.7
245
2 - - 0.0
241
2 - - 0.0
266
2 - - 36.2
231
2 - - 10.6
261
2 - - 35.5
223
2 - - 3.2
216
2 - - 33.7
350
1 - - 0.0
340
1 - - 0.0
311
1 - - 0.0
285
1 - - 0.0
308
1 - - 0.0
301
1 - - 0.0
272
1 - - 0.0
294
1 - - 0.0
349
1 - - 0.0
323
1 - - 0.0
330
1 - - 0.0
353
1 - - 0.0
278
1 - - 0.0
307
1 - - 0.0
326
1 - - 0.0
335
1 - - 0.0
299
1 - - 0.0
315
1 - - 0.0
305
1 - - 0.0
281
1 - - 0.0
317
1 - - 0.0
284
1 - - 0.0
289
1 - - 0.0
319
1 - - 0.0
344
1 - - 0.0
336
1 - - 0.0
290
1 - - 0.0
271
1 - - 0.0
351
1 - - 0.0
342
1 - - 0.0
309
1 - - 0.0
329
1 - - 0.0
346
1 - - 0.0
279
1 - - 0.0
293
1 - - 0.0
322
1 - - 0.0
310
1 - - 0.0
354
1 - - 0.0
316
1 - - 0.0
280
1 - - 0.0
273
1 - - 0.0
314
1 - - 0.0
355
1 - - 0.0
334
1 - - 0.0
302
1 - - 0.0
298
1 - - 0.0
339
1 - - 0.0
345
1 - - 0.0
318
1 - - 0.0
325
1 - - 0.0
337
1 - - 0.0
288
1 - - 0.0
287
1 - - 0.0
333
1 - - 0.0
274
1 - - 0.0
303
1 - - 0.0
276
1 - - 0.0
347
1 - - 0.0
320
1 - - 0.0
338
1 - - 0.0
328
1 - - 0.0
313
1 - - 0.0
297
1 - - 0.0
283
1 - - 0.0
331
1 - - 0.0
348
1 - - 0.0
324
1 - - 0.0
295
1 - - 0.0
312
1 - - 0.0
300
1 - - 0.0
286
1 - - 0.0
296
1 - - 0.0
275
1 - - 0.0
352
1 - - 0.0
332
1 - - 0.0
292
1 - - 0.0
291
1 - - 0.0
327
1 - - 0.0
270
1 - - 0.0
343
1 - - 0.0
321
1 - - 0.0
282
1 - - 0.0
277
1 - - 0.0
304
1 - - 0.0
306
1 - - 0.0