The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Zn peptidases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
615
3D
1zliA00 - 92.0
2
528
3D
1vixB01 - 88.7
3
511
3D
5jh9D01 - 93.2
4
476
3D
1gytL02 - 73.7
5
409 - - 72.8
6
407
3D
1ysjB01 - 92.9
7
M14 family
399 - - 87.6
8
382 - - 95.5
9
365 - - 93.5
10
359 - - 74.4
33
336
3D
4x2tL02 - 73.3
11
284 - - 80.0
12
264 - - 77.1
14
252
3D
2zogB01 - 95.1
13
246
3D
2nsmA01 - 91.0
15
243
3D
3mruB01 - 93.1
16
239
3D
2q43A01 - 81.6
17
235
3D
1yw6B00 - 75.5
19
225
3D
1q7lC00 - 94.5
18
224 - - 89.2
20
209
3D
1qmuA01 - 93.5
29
184
3D
6gbxC00 - 94.2
21
166 - - 84.9
25
157
3D
4tnuB01 - 88.8
22
156 - - 76.2
23
141 - - 76.5
35
139
3D
5ntdL02 - 71.5
24
138 - - 59.0
26
127 - - 84.0
27
124 - - 93.1
28
123
3D
3gb0A01 - 18.7
31
121
3D
2j9aA02 - 79.5
59
117
3D
6hkzA01 - 41.6
30
114 - - 76.9
32
108
3D
5hxdB00 - 47.5
34
101
3D
3tx8A01 - 72.3
36
97 - - 83.4
45
93
3D
6d05B01 - 70.8
44
90
3D
4pxeB01 - 88.2
37
87 - - 56.0
132
87
3D
6i6zB00 - 72.6
38
86 - - 51.4
39
84 - - 87.7
40
83 - - 95.6
41
80
3D
1uwyA01 - 71.5
43
79 - - 82.7
42
79 - - 93.2
46
66 - - 79.4
47
66 - - 88.0
48
61 - - 56.4
49
61 - - 49.7
50
60
3D
5mrvB00 - 80.1
53
59
3D
3pb9X00 - 56.2
51
57 - - 48.7
52
54 - - 87.5
54
52 - - 88.4
55
49 - - 44.6
56
48 - - 89.5
66
44
3D
1xjoA00 - 76.1
58
43 - - 5.9
57
43 - - 89.9
60
42 - - 83.9
76
41
3D
5hvhA02 - 73.5
61
38 - - 71.5
62
37 - - 58.7
63
36 - - 70.2
65
34 - - 98.0
64
34 - - 80.6
71
32
3D
3ramD01 - 71.8
67
32 - - 33.1
68
32 - - 84.8
69
31 - - 85.2
70
30 - - 76.2
72
28 - - 83.7
73
25 - - 78.3
74
24 - - 72.5
75
23 - - 77.2
78
22 - - 72.6
80
22 - - 87.3
90
22
3D
4emeD01 - 71.1
77
22 - - 76.0
79
22 - - 57.7
82
21 - - 33.6
81
21 - - 77.7
83
21 - - 74.9
89
20
3D
4tweB01 - 74.4
84
20 - - 82.5
85
19 - - 73.0
87
19 - - 23.8
86
19 - - 22.9
88
19 - - 89.8
92
18 - - 76.0
91
18 - - 2.3
93
18 - - 75.9
96
17 - - 5.7
94
17 - - 57.7
98
17 - - 80.6
95
17 - - 29.8
97
17 - - 63.0
99
16 - - 24.0
106
16
3D
3mn8D01 - 53.8
100
15 - - 63.5
101
15 - - 99.4
103
14 - - 14.6
102
14 - - 22.2
104
14 - - 58.5
105
13 - - 16.2
112
12 - - 79.9
110
12 - - 16.9
109
12 - - 21.8
107
12 - - 16.1
111
12 - - 34.5
108
12 - - 15.5
117
11 - - 89.9
115
11 - - 81.5
113
11 - - 16.3
116
11 - - 63.3
114
11 - - 43.9
124
10 - - 30.4
119
10 - - 44.7
121
GAA1
10 - - 61.1
123
10 - - 37.6
125
10 - - 75.8
118
10 - - 66.5
120
10 - - 8.8
122
10 - - 64.7
129
9 - - 25.2
131
9 - - 86.1
126
9 - - 20.2
130
9 - - 6.4
128
9 - - 14.6
127
9 - - 43.9
133
8 - - 0.0
137
8 - - 6.8
135
8 - - 0.0
134
8 - - 0.0
136
8 - - 7.4
138
8 - - 73.0
148
7 - - 5.9
141
7 - - 10.1
143
7 - - 0.4
147
7 - - 0.0
145
7 - - 12.0
140
7 - - 9.1
150
7 - - 86.6
142
7 - - 7.9
149
7 - - 5.9
139
7 - - 38.3
144
7 - - 1.0
146
7 - - 15.5
165
6 - - 83.4
157
6 - - 8.6
163
6 - - 10.6
154
6 - - 0.0
152
6 - - 62.5
160
6 - - 16.8
159
6 - - 7.0
162
6 - - 8.6
158
6 - - 5.9
156
6 - - 78.1
153
6 - - 4.8
155
6 - - 75.3
161
6 - - 7.7
164
6 - - 39.8
151
6 - - 43.2
170
5 - - 82.7
168
5 - - 1.9
176
5 - - 72.8
175
5 - - 6.4
167
5 - - 0.0
169
5 - - 5.4
172
5 - - 5.1
178
5 - - 72.6
177
5 - - 84.3
171
5 - - 0.4
166
5 - - 75.4
174
5 - - 0.0
173
5 - - 1.8
184
4 - - 72.2
181
4 - - 0.0
192
4 - - 5.6
199
4 - - 88.9
179
4 - - 68.3
193
4 - - 10.2
186
4 - - 57.4
180
4 - - 9.6
187
4 - - 19.3
200
4 - - 76.3
189
4 - - 14.9
182
4 - - 33.0
197
4 - - 71.8
190
4 - - 11.8
191
4 - - 1.0
183
4 - - 38.1
196
4 - - 72.5
194
4 - - 7.9
185
4 - - 84.0
198
4 - - 47.2
195
Homolog to aminopeptidase YwaD
4 - - 31.9
188
4 - - 18.8
207
3 - - 1.6
224
3 - - 74.1
205
3 - - 7.9
215
3 - - 2.1
212
3 - - 2.0
202
3 - - 30.5
211
3 - - 7.2
218
3 - - 34.2
221
3 - - 78.1
206
3 - - 3.7
223
3 - - 46.6
216
3 - - 5.1
222
3 - - 71.4
217
3 - - 3.7
209
3 - - 9.3
204
3 - - 9.8
214
3 - - 7.3
210
3 - - 8.5
213
3 - - 0.5
203
3 - - 2.9
219
3 - - 9.6
220
3 - - 24.9
208
3 - - 35.6
201
3 - - 8.7
294
2 - - 4.1
232
2 - - 48.4
305
2 - - 33.2
281
2 - - 0.4
252
2 - - 10.3
279
2 - - 3.5
263
2 - - 0.4
310
2 - - 34.4
273
2 - - 2.1
258
2 - - 34.4
248
2 - - 7.0
234
2 - - 45.5
288
2 - - 0.0
264
2 - - 7.7
297
2 - - 31.4
283
2 - - 0.0
226
2 - - 28.0
237
2 - - 8.7
300
2 - - 32.5
256
2 - - 37.6
270
2 - - 0.0
261
2 - - 22.3
285
2 - - 0.0
257
2 - - 38.3
307
2 - - 33.8
299
2 - - 31.0
247
2 - - 0.0
289
2 - - 0.0
290
2 - - 0.0
242
2 - - 0.0
309
2 - - 35.2
254
2 - - 11.2
316
2 - - 0.0
314
2 - - 40.8
302
2 - - 30.2
228
2 - - 0.4
287
2 - - 5.0
274
2 - - 7.8
250
2 - - 0.0
276
2 - - 0.0
240
2 - - 7.6
230
2 - - 43.5
239
2 - - 0.0
269
2 - - 8.9
312
2 - - 36.4
245
2 - - 4.4
266
2 - - 0.0
304
2 - - 30.6
311
2 - - 38.5
272
2 - - 0.0
262
2 - - 7.2
225
2 - - 0.0
278
2 - - 7.2
293
2 - - 9.3
267
2 - - 0.0
233
2 - - 45.2
280
2 - - 0.0
253
2 - - 28.0
236
2 - - 0.0
260
2 - - 40.2
227
2 - - 44.4
259
2 - - 40.6
249
2 - - 4.6
244
2 - - 28.8
295
2 - - 0.6
235
2 - - 13.2
296
2 - - 28.3
265
2 - - 0.4
282
2 - - 48.5
306
2 - - 35.1
246
2 - - 1.5
308
2 - - 35.6
301
plasma
2 - - 32.1
229
2 - - 20.4
315
2 - - 41.6
317
2 - - 50.6
284
2 - - 0.0
271
2 - - 0.0
298
2 - - 31.7
243
2 - - 2.4
268
2 - - 5.6
238
2 - - 2.2
255
2 - - 17.2
303
2 - - 0.0
313
2 - - 38.3
286
2 - - 44.1
275
2 - - 2.4
251
2 - - 7.5
292
2 - - 51.9
291
2 - - 32.9
241
2 - - 11.1
231
2 - - 43.9
277
2 - - 1.1
506
1 - - 0.0
468
1 - - 0.0
413
1 - - 0.0
490
1 - - 0.0
461
1 - - 0.0
412
1 - - 0.0
326
1 - - 0.0
474
1 - - 0.0
319
1 - - 0.0
336
1 - - 0.0
457
1 - - 0.0
383
1 - - 0.0
419
1 - - 0.0
365
1 - - 0.0
408
1 - - 0.0
431
1 - - 0.0
351
1 - - 0.0
405
1 - - 0.0
392
1 - - 0.0
427
1 - - 0.0
426
1 - - 0.0
483
1 - - 0.0
471
1 - - 0.0
334
1 - - 0.0
439
1 - - 0.0
376
1 - - 0.0
371
1 - - 0.0
345
1 - - 0.0
451
1 - - 0.0
415
1 - - 0.0
320
1 - - 0.0
465
1 - - 0.0
385
1 - - 0.0
338
1 - - 0.0
328
1 - - 0.0
401
1 - - 0.0
437
1 - - 0.0
496
1 - - 0.0
441
1 - - 0.0
394
1 - - 0.0
374
1 - - 0.0
429
1 - - 0.0
489
1 - - 0.0
478
1 - - 0.0
343
1 - - 0.0
420
1 - - 0.0
512
1 - - 0.0
463
1 - - 0.0
391
1 - - 0.0
456
1 - - 0.0
366
1 - - 0.0
323
1 - - 0.0
477
1 - - 0.0
449
1 - - 0.0
387
1 - - 0.0
361
1 - - 0.0
443
1 - - 0.0
509
1 - - 0.0
341
1 - - 0.0
372
1 - - 0.0
476
1 - - 0.0
354
1 - - 0.0
502
1 - - 0.0
423
1 - - 0.0
422
1 - - 0.0
435
1 - - 0.0
487
1 - - 0.0
396
Fragment
1 - - 0.0
482
1 - - 0.0
499
1 - - 0.0
450
1 - - 0.0
356
1 - - 0.0
454
1 - - 0.0
325
1 - - 0.0
389
1 - - 0.0
410
1 - - 0.0
480
1 - - 0.0
417
1 - - 0.0
381
1 - - 0.0
333
1 - - 0.0
510
1 - - 0.0
393
1 - - 0.0
363
1 - - 0.0
459
1 - - 0.0
404
1 - - 0.0
358
1 - - 0.0
331
1 - - 0.0
348
1 - - 0.0
379
1 - - 0.0
370
1 - - 0.0
445
Putative secreted protein
1 - - 0.0
368
1 - - 0.0
492
1 - - 0.0
327
1 - - 0.0
433
1 - - 0.0
497
1 - - 0.0
398
1 - - 0.0
504
1 - - 0.0
458
1 - - 0.0
350
1 - - 0.0
495
1 - - 0.0
486
1 - - 0.0
432
1 - - 0.0
359
1 - - 0.0
425
1 - - 0.0
395
1 - - 0.0
335
1 - - 0.0
440
1 - - 0.0
467
1 - - 0.0
472
1 - - 0.0
344
1 - - 0.0
505
1 - - 0.0
406
1 - - 0.0
382
1 - - 0.0
453
1 - - 0.0
507
1 - - 0.0
329
1 - - 0.0
346
1 - - 0.0
498
1 - - 0.0
414
1 - - 0.0
462
1 - - 0.0
469
1 - - 0.0
362
1 - - 0.0
407
1 - - 0.0
318
1 - - 0.0
473
1 - - 0.0
337
1 - - 0.0
430
1 - - 0.0
447
1 - - 0.0
438
1 - - 0.0
493
1 - - 0.0
400
1 - - 0.0
442
1 - - 0.0
479
1 - - 0.0
377
1 - - 0.0
484
1 - - 0.0
397
1 - - 0.0
470
1 - - 0.0
364
1 - - 0.0
460
1 - - 0.0
452
1 - - 0.0
416
1 - - 0.0
352
1 - - 0.0
428
1 - - 0.0
500
1 - - 0.0
409
1 - - 0.0
384
1 - - 0.0
321
1 - - 0.0
466
1 - - 0.0
340
1 - - 0.0
444
1 - - 0.0
508
1 - - 0.0
349
1 - - 0.0
330
1 - - 0.0
360
1 - - 0.0
353
1 - - 0.0
375
1 - - 0.0
501
1 - - 0.0
481
1 - - 0.0
421
1 - - 0.0
491
1 - - 0.0
367
1 - - 0.0
488
1 - - 0.0
342
1 - - 0.0
399
1 - - 0.0
436
1 - - 0.0
386
1 - - 0.0
322
1 - - 0.0
511
1 - - 0.0
355
1 - - 0.0
402
1 - - 0.0
464
1 - - 0.0
339
1 - - 0.0
494
1 - - 0.0
448
1 - - 0.0
378
1 - - 0.0
373
1 - - 0.0
475
1 - - 0.0
446
1 - - 0.0
424
1 - - 0.0
347
1 - - 0.0
434
1 - - 0.0
503
1 - - 0.0
357
1 - - 0.0
455
1 - - 0.0
390
1 - - 0.0
418
1 - - 0.0
388
1 - - 0.0
485
1 - - 0.0
324
1 - - 0.0
380
1 - - 0.0
369
1 - - 0.0
332
1 - - 0.0
411
Homo sapiens
1 - - 0.0
403
1 - - 0.0