CATH Classification

Domain Context

CATH Clusters

Superfamily Zn peptidases
Functional Family Carboxypeptidase A1

Enzyme Information

3.4.17.1
Carboxypeptidase A.
based on mapping to UniProt P15085
Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.
-!- Isolated from cattle, pig and dogfish pancreas, and other sources including mast cells and skeletal muscle. -!- Belongs to peptidase family M14. -!- Formerly EC 3.4.2.1 and EC 3.4.12.2.

UniProtKB Entries (1)

P15085
CBPA1_HUMAN
Homo sapiens
Carboxypeptidase A1

PDB Structure

PDB 6I6Z
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Synthesis and Structural/Functional Characterization of Selective M14 Metallocarboxypeptidase Inhibitors Based on Phosphinic Pseudopeptide Scaffold: Implications on the Design of Specific Optical Probes.
Covaleda, G., Gallego, P., Vendrell, J., Georgiadis, D., Lorenzo, J., Dive, V., Aviles, F.X., Reverter, D., Devel, L.
J. Med. Chem.