The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Thymidylate synthase/dCMP hydroxymethylase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
900
3D
6nnrB00 - 80.5
2
416
3D
5fctB00 - 84.2
4
72
3D
3dgaD00 - 29.1
3
55 - - 41.8
5
43 - - 67.1
6
31 - - 19.3
12
27
3D
2aazP00 - 10.0
7
24
3D
6qyqA00 - 25.0
10
23
3D
1bspB00 - 42.4
16
22
3D
5nooD00 - 32.0
8
20 - - 13.6
9
16
3D
1tisA00 - 61.1
11
12 - - 29.5
14
9 - - 8.6
13
9 - - 78.1
15
7 - - 0.8
17
5 - - 10.0
18
4 - - 52.1
19
4 - - 43.8
20
3 - - 14.2
22
2 - - 3.8
21
2 - - 0.4
23
2 - - 4.4
29
1 - - 0.0
26
1 - - 0.0
33
1 - - 0.0
30
1 - - 0.0
25
1 - - 0.0
32
1 - - 0.0
31
1 - - 0.0
27
1 - - 0.0
28
1 - - 0.0
24
1 - - 0.0