The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
774
3D
2bkdN02 - 89.4
2
715
3D
4qw2B01 - 93.8
3
652 - - 42.0
5
618
3D
5varA01 - 97.7
4
597
3D
2daqA00 - 87.6
7
3
578
3D
3uwnA03 - 83.2
6
Cytosine-5
547
3D
1khcA01 - 76.2
8
516
3D
5c6sA01 - 84.7
9
493
3D
2mamA00 - 77.4
10
480
3D
4c5hA03 - 93.1
11
410
3D
4ns5A02 - 53.0
12
384
3D
6bphA00 - 83.4
13
347
3D
4qqgG00 - 94.9
15
342
3D
4c5hA01 - 77.6
16
331
3D
2r5mA02 - 59.7
17
329
3D
2nluB00 - 90.8
14
328
3D
2eqjA00 - 75.4
21
323
3D
1ssfA01 - 96.0
18
314
3D
2wacB02 - 99.5
19
307
3D
4c5hA02 - 77.4
20
295
3D
6bogB01 - 61.1
22
295
3D
3vyrA00 - 86.8
25
3
284
3D
3uwnA01 - 76.9
23
283
3D
2ot2A01 - 18.7
24
274
3D
2efiA00 - 94.0
28
226
3D
2r5mA01 - 80.8
26
225
3D
3lx7A01 - 95.3
29
224
3D
5c0mB02 - 92.8
27
218 - - 60.4
32
211
3D
3f70B04 - 62.9
30
205 - - 69.5
31
204
3D
2ckkA01 - 84.0
33
195 - - 88.7
34
184 - - 75.7
37
175
3D
6bhiA03 - 65.9
35
171 - - 69.4
38
168
3D
4qq6A00 - 77.1
36
163
3D
4ld6A00 - 87.0
39
162
3D
1wgsA00 - 86.2
42
162
3D
3m9qB00 - 90.5
40
161
3D
2m0oA00 - 32.7
41
154 - - 63.2
46
147
3D
5yj8A00 - 65.1
43
Predicted
141
3D
3qiiA00 - 58.9
47
141
3D
5m9oA02 - 79.7
44
138 - - 76.3
45
137 - - 72.0
49
Predicted
129
3D
3sd4B00 - 65.2
48
127 - - 78.7
54
126
3D
6bhiA01 - 49.8
50
RBP1-like
125
3D
2yrvA01 - 72.7
51
123 - - 72.2
52
116 - - 75.8
55
115
3D
3mp8A05 - 80.7
53
113 - - 72.0
56
107 - - 75.7
57
107 - - 88.4
58
104
3D
2digA00 - 90.4
59
100 - - 89.2
60
98 - - 54.3
61
90 - - 92.2
63
90
3D
3pmiD01 - 76.1
68
89
3D
5iayA01 - 82.0
62
87 - - 19.1
64
84 - - 48.8
65
83 - - 94.4
66
82 - - 28.0
71
77
3D
4ii1D02 - 71.3
67
77 - - 77.6
69
75
3D
2gfuA00 - 74.8
70
75
3D
1wjrA00 - 44.1
72
71 - - 72.9
74
70 - - 56.8
73
70 - - 88.3
75
63 - - 91.8
76
62 - - 41.6
77
61 - - 51.5
78
60 - - 11.0
80
57 - - 71.6
79
57 - - 81.2
81
56
3D
4b9xA02 - 73.4
82
52
3D
3o8vA02 - 37.3
84
50
3D
5j39B02 - 71.8
83
48 - - 31.7
85
37 - - 65.3
87
35 - - 87.6
86
35 - - 21.6
88
32 - - 75.5
89
31 - - 25.7
92
30 - - 89.5
90
30 - - 45.0
91
30 - - 70.6
93
28 - - 82.1
94
27 - - 58.5
95
27 - - 35.4
96
24 - - 36.3
97
23 - - 63.0
99
21 - - 95.3
98
21 - - 20.2
103
19 - - 91.1
102
19 - - 70.1
100
19 - - 46.2
101
19 - - 4.7
123
18
3D
3e9gB01 - 53.2
104
18 - - 70.2
105
17 - - 54.6
106
17 - - 10.3
107
16 - - 78.9
112
15 - - 30.7
110
15 - - 6.3
109
15 - - 63.7
111
15 - - 18.3
113
15 - - 71.8
108
15 - - 55.2
120
15
3D
2l89A00 - 90.3
114
15 - - 97.2
115
14 - - 70.4
116
14 - - 6.2
129
13
3D
2lrqA00 - 81.8
124
13 - - 51.8
119
13 - - 8.2
117
13 - - 24.0
121
13 - - 28.3
125
13 - - 84.3
118
13 - - 10.4
122
13 - - 52.4
141
Rad9
12
3D
2fhdC01 - 88.3
126
12 - - 36.2
128
NAD
P
12 - - 13.6
127
12 - - 16.4
131
11 - - 34.0
133
11 - - 11.6
130
11 - - 21.4
304
11
3D
4iuvB02 - 0.0
132
11 - - 14.2
137
10 - - 17.9
135
10 - - 53.0
140
Mortality factor-Related Gene
10 - - 81.8
139
10 - - 26.6
134
10 - - 47.8
136
10 - - 19.5
138
10 - - 26.0
143
9 - - 13.9
172
9
3D
3ntkB02 - 23.1
142
9 - - 0.0
144
9 - - 64.8
148
8 - - 27.5
147
8 - - 13.5
145
8 - - 65.5
160
8
3D
4q5wB02 - 11.4
150
8 - - 19.4
149
8 - - 80.3
146
8 - - 6.6
154
7 - - 66.7
152
7 - - 7.7
156
7 - - 91.2
153
7 - - 23.4
155
7 - - 85.0
151
7 - - 6.3
157
6 - - 38.1
163
6 - - 4.7
159
6 - - 8.8
162
6 - - 4.4
158
6 - - 16.3
161
6 - - 5.4
170
cytosine-5-
5 - - 0.0
165
5 - - 1.4
168
Qin
5 - - 14.3
176
5 - - 91.6
175
5 - - 13.4
167
5 - - 3.3
169
cytosine-5-
5 - - 1.7
178
5 - - 87.7
177
5 - - 62.5
171
5 - - 2.3
166
5 - - 13.2
174
5 - - 19.5
164
5 - - 45.8
173
5 - - 8.2
184
4 - - 10.8
181
4 - - 46.4
192
4 - - 4.8
179
4 - - 17.2
193
4 - - 8.4
186
4 - - 0.0
180
4 - - 25.9
187
4 - - 5.0
189
4 - - 14.0
182
4 - - 60.7
190
4 - - 8.8
191
4 - - 12.9
183
4 - - 11.0
194
4 - - 87.8
185
4 - - 15.7
195
4 - - 84.2
188
4 - - 0.0
207
3 - - 11.3
199
3 - - 7.2
205
3 - - 4.8
215
3 - - 7.1
212
3 - - 23.4
202
3 - - 0.0
200
3 - - 13.0
211
3 - - 11.2
206
3 - - 2.0
197
3 - - 30.8
209
3 - - 36.2
204
3 - - 0.0
214
3 - - 0.9
196
3 - - 43.4
198
3 - - 8.8
210
3 - - 11.7
213
3 - - 39.3
203
3 - - 0.0
208
3 - - 10.9
201
3 - - 11.3
232
2 - - 0.0
252
2 - - 4.0
224
2 - - 0.0
263
2 - - 0.0
273
2 - - 0.0
258
2 - - 0.0
248
2 - - 0.0
234
2 - - 1.6
264
2 - - 0.9
226
2 - - 0.0
237
2 - - 1.0
256
2 - - 34.4
270
2 - - 6.7
261
2 - - 41.0
257
2 - - 0.0
247
2 - - 3.8
242
2 - - 2.8
254
2 - - 6.9
228
2 - - 0.0
218
RNA interference
2 - - 48.2
221
2 - - 0.0
274
2 - - 0.0
250
2 - - 0.0
276
2 - - 40.1
240
2 - - 1.8
230
2 - - 12.6
239
2 - - 0.0
269
2 - - 5.0
245
2 - - 7.8
266
2 - - 26.3
223
2 - - 9.6
216
2 - - 35.0
272
2 - - 0.0
262
2 - - 0.0
225
2 - - 0.0
278
2 - - 42.4
222
2 - - 11.2
217
2 - - 39.5
267
2 - - 45.1
233
Qin
2 - - 0.0
253
2 - - 0.0
236
2 - - 0.0
260
2 - - 0.0
227
2 - - 0.0
259
2 - - 0.0
249
2 - - 0.0
244
AT-rich Interactive Domain-containing protein
2 - - 0.0
235
2 - - 1.6
265
2 - - 0.0
246
2 - - 0.0
229
2 - - 0.0
271
2 - - 0.0
243
2 - - 0.0
268
2 - - 0.0
238
2 - - 0.0
255
2 - - 47.1
219
2 - - 5.7
220
RNA interference
2 - - 46.9
275
Human Survival Motor Neuron gene
2 - - 0.0
251
2 - - 0.0
241
2 - - 0.0
231
2 - - 0.0
277
2 - - 11.7
294
1 - - 0.0
326
1 - - 0.0
305
1 - - 0.0
281
1 - - 0.0
319
1 - - 0.0
336
1 - - 0.0
351
1 - - 0.0
279
1 - - 0.0
310
1 - - 0.0
334
1 - - 0.0
345
1 - - 0.0
288
1 - - 0.0
320
1 - - 0.0
338
NUC162
1 - - 0.0
328
1 - - 0.0
297
1 - - 0.0
283
1 - - 0.0
300
1 - - 0.0
343
1 - - 0.0
285
1 - - 0.0
323
1 - - 0.0
307
1 - - 0.0
299
1 - - 0.0
289
1 - - 0.0
290
1 - - 0.0
341
1 - - 0.0
309
1 - - 0.0
316
1 - - 0.0
314
1 - - 0.0
302
1 - - 0.0
325
1 - - 0.0
287
1 - - 0.0
333
1 - - 0.0
331
1 - - 0.0
348
1 - - 0.0
312
1 - - 0.0
327
1 - - 0.0
350
1 - - 0.0
311
1 - - 0.0
335
1 - - 0.0
344
1 - - 0.0
329
1 - - 0.0
346
1 - - 0.0
293
1 - - 0.0
280
1 - - 0.0
318
1 - - 0.0
337
1 - - 0.0
295
1 - - 0.0
296
1 - - 0.0
352
1 - - 0.0
321
1 - - 0.0
282
1 - - 0.0
306
1 - - 0.0
340
1 - - 0.0
308
1 - - 0.0
301
1 - - 0.0
349
1 - - 0.0
330
1 - - 0.0
353
1 - - 0.0
315
1 - - 0.0
317
1 - - 0.0
284
1 - - 0.0
342
1 - - 0.0
322
1 - - 0.0
298
1 - - 0.0
339
NUC162
1 - - 0.0
303
1 - - 0.0
347
1 - - 0.0
313
1 - - 0.0
324
1 - - 0.0
286
1 - - 0.0
332
1 - - 0.0
292
1 - - 0.0
291
1 - - 0.0