CATH Classification

Domain Context

CATH Clusters

Superfamily 2.30.30.140
Functional Family Lamin B receptor

Enzyme Information

1.3.1.70
Delta(14)-sterol reductase.
based on mapping to UniProt Q14739
4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NADP(+) = 4,4- dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol + NADPH.
-!- Acts on a range of steroids with a 14(15)-double bond.

UniProtKB Entries (1)

Q14739
LBR_HUMAN
Homo sapiens
Delta(14)-sterol reductase

PDB Structure

PDB 2DIG
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solusion structure of the Todor domain of human Lamin-B receptor
Yoneyama, M., Tochio, N., Koshiba, S., Inoue, M., Kigawa, T., Yokoyama, S.
To be Published