The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
SET domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
812
3D
4mi5A00 - 82.6
2
572
3D
3ooiA00 - 78.0
3
537
3D
4z4pA00 - 85.2
5
481
3D
5vseB00 - 66.4
4
481 - - 73.4
6
350
3D
4au7B02 - 89.0
7
334
3D
3ihxD01 - 82.8
8
284
3D
2r3aA00 - 78.0
9
223 - - 65.5
10
197 - - 74.1
11
193
3D
4ypuB00 - 72.8
16
157
3D
5lszA00 - 77.6
13
156 - - 97.4
12
156 - - 76.8
14
155
3D
3rayA00 - 58.5
15
154 - - 62.1
17
146 - - 78.6
24
142
3D
5yltA02 - 58.8
21
140
3D
6bozB00 - 64.8
19
130
3D
3dalB00 - 83.3
18
129 - - 48.0
20
118 - - 58.6
22
107 - - 59.8
23
104 - - 74.5
25
99 - - 68.6
26
92
3D
2jv0A01 - 40.0
27
57 - - 62.1
28
56 - - 82.7
31
55
3D
4c1qB00 - 89.9
29
54 - - 89.6
39
54
3D
5v37A01 - 53.7
30
53 - - 20.3
32
49 - - 70.2
38
49
3D
5vbcB00 - 73.5
33
48 - - 70.7
34
47 - - 71.0
35
45 - - 76.3
36
43 - - 86.4
37
41 - - 64.2
41
30
3D
3bo5A00 - 63.2
40
30 - - 51.0
43
25 - - 75.6
42
25 - - 12.5
44
23 - - 89.2
50
18
3D
3kmaB00 - 85.1
45
18 - - 34.1
51
16
3D
6a5nA03 - 80.7
46
16 - - 59.4
49
16
3D
4rz0B00 - 12.5
48
15 - - 0.0
47
15 - - 13.0
52
13 - - 17.4
56
12 - - 57.7
53
12 - - 74.8
55
12 - - 12.0
54
12 - - 30.4
58
11 - - 66.8
57
11 - - 81.0
60
10 - - 20.1
62
10 - - 65.2
61
10 - - 4.6
59
10 - - 0.0
65
9 - - 13.4
67
9 - - 12.1
63
9 - - 2.9
64
9 - - 8.8
66
9 - - 79.3
69
8 - - 18.6
71
8 - - 6.6
74
8 - - 74.9
72
Trithorax/polycomb
8 - - 17.1
68
8 - - 2.0
70
8 - - 14.8
73
8 - - 51.4
76
7 - - 46.2
98
7
3D
4qepA03 - 9.3
77
7 - - 13.9
75
7 - - 31.5
78
6 - - 54.3
80
Trithorax/polycomb
6 - - 19.0
82
6 - - 45.3
85
6
3D
4nj5A02 - 32.9
81
6 - - 13.3
79
6 - - 10.9
83
6 - - 32.5
89
5 - - 35.0
92
5 - - 10.9
90
5 - - 9.6
84
5 - - 4.2
96
5 - - 69.3
94
5 - - 9.9
87
5 - - 18.8
91
5 - - 8.8
93
5 - - 10.0
95
5 - - 14.6
86
5 - - 56.3
88
5 - - 80.9
105
4 - - 41.8
99
var
4 - - 20.2
103
4 - - 8.1
102
4 - - 6.9
100
4 - - 21.9
101
4 - - 41.5
106
4 - - 70.0
104
4 - - 0.0
97
4 - - 73.7
112
3 - - 28.2
119
3 - - 28.2
110
3 - - 3.8
117
3 - - 2.2
109
3 - - 4.6
107
3 - - 15.3
115
3 - - 8.5
111
3 - - 30.5
113
3 - - 35.8
118
3 - - 4.8
116
3 - - 6.9
108
3 - - 5.3
208
3
3D
1mvxA00 - 0.0
114
3 - - 70.2
129
2 - - 6.5
124
2 - - 14.2
131
2 - - 0.0
148
2 - - 42.2
141
2 - - 8.7
126
2 - - 10.8
143
2 - - 0.0
133
2 - - 30.8
137
2 - - 9.5
147
2 - - 36.4
135
2 - - 42.7
145
2 - - 0.0
121
2 - - 37.8
130
2 - - 0.0
140
2 - - 9.5
150
2 - - 25.2
123
2 - - 9.1
142
2 - - 0.0
128
2 - - 11.5
132
2 - - 7.8
149
2 - - 29.4
139
2 - - 0.0
144
2 - - 10.9
125
2 - - 36.1
134
2 - - 38.7
127
AFU_orthologue AFUA_1G11090
2 - - 0.0
136
2 - - 20.0
120
2 - - 34.1
146
2 - - 37.4
138
2 - - 0.9
122
Trithorax/polycomb
2 - - 35.3
170
1 - - 0.0
232
1 - - 0.0
207
1 - - 0.0
184
1 - - 0.0
181
1 - - 0.0
165
1 - - 0.0
168
1 - - 0.0
224
1 - - 0.0
192
1 - - 0.0
199
1 - - 0.0
157
1 - - 0.0
179
1 - - 0.0
234
1 - - 0.0
193
1 - - 0.0
205
1 - - 0.0
163
1 - - 0.0
186
1 - - 0.0
226
1 - - 0.0
237
1 - - 0.0
176
1 - - 0.0
215
1 - - 0.0
180
1 - - 0.0
187
1 - - 0.0
212
1 - - 0.0
175
1 - - 0.0
202
1 - - 0.0
154
1 - - 0.0
242
1 - - 0.0
152
1 - - 0.0
200
1 - - 0.0
228
1 - - 0.0
211
1 - - 0.0
218
1 - - 0.0
160
1 - - 0.0
189
1 - - 0.0
221
1 - - 0.0
182
1 - - 0.0
167
1 - - 0.0
240
1 - - 0.0
230
1 - - 0.0
239
1 - - 0.0
206
1 - - 0.0
197
1 - - 0.0
159
1 - - 0.0
162
1 - - 0.0
169
1 - - 0.0
190
1 - - 0.0
172
1 - - 0.0
223
1 - - 0.0
216
1 - - 0.0
191
1 - - 0.0
225
1 - - 0.0
222
1 - - 0.0
217
1 - - 0.0
158
1 - - 0.0
209
1 - - 0.0
178
1 - - 0.0
233
1 - - 0.0
183
1 - - 0.0
204
1 - - 0.0
236
1 - - 0.0
177
1 - - 0.0
227
1 - - 0.0
214
1 - - 0.0
156
1 - - 0.0
196
1 - - 0.0
194
1 - - 0.0
235
1 - - 0.0
171
1 - - 0.0
166
1 - - 0.0
185
1 - - 0.0
153
1 - - 0.0
155
1 - - 0.0
198
1 - - 0.0
229
1 - - 0.0
210
1 - - 0.0
213
1 - - 0.0
161
1 - - 0.0
195
1 - - 0.0
174
1 - - 0.0
188
1 - - 0.0
243
1 - - 0.0
203
1 - - 0.0
238
1 - - 0.0
164
1 - - 0.0
151
Trithorax/polycomb
1 - - 0.0
173
1 - - 0.0
219
1 - - 0.0
220
1 - - 0.0
241
1 - - 0.0
201
1 - - 0.0
231
1 - - 0.0