CATH Classification

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family Histone-lysine N-methyltransferase

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q9NQR1
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
2.1.1.-
Methyltransferases.
based on mapping to UniProt Q9NQR1

UniProtKB Entries (1)

Q9NQR1
KMT5A_HUMAN
Homo sapiens
N-lysine methyltransferase KMT5A

PDB Structure

PDB 6BOZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The dynamic conformational landscape of the protein methyltransferase SETD8.
Chen, S., Wiewiora, R.P., Meng, F., Babault, N., Ma, A., Yu, W., Qian, K., Hu, H., Zou, H., Wang, J., Fan, S., Blum, G., Pittella-Silva, F., Beauchamp, K.A., Tempel, W., Jiang, H., Chen, K., Skene, R.J., Zheng, Y.G., Brown, P.J., Jin, J., Luo, C., Chodera, J.D., Luo, M.
Elife