CATH Superfamily 3.30.565.10

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Enzyme?	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
80954	Multi-sensor hybrid histidine kinase	36033	EC	3D	4gczA04	-	93.3
33235	Histidine kinase	33649	EC	3D	4biuA02	-	59.1
80828	DNA gyrase subunit B	30193	EC	3D	4i3hA01	-	91.9
5449	Histidine kinase	25987	EC		-	-	84.0
80486	Aerobic respiration control sensor protein	22857	EC		-	-	84.1
80823	Sensor histidine kinase PhoQ	21680	EC	3D	1id0A00	-	88.9
42269	Inner membrane protein yehU	19338	EC		-	-	10.3
80199	Histidine kinase	17254	EC	3D	4kp4A02	-	40.1
80741	Anti-sigma F factor protein	14654	EC	3D	1l0oA00	-	91.1
80793	Heat shock protein 90	10852	EC	3D	1byqA00	-	85.2
80871	Histidine kinase	10530	EC		-	-	68.1
80880	Multi-sensor hybrid histidine kinase	9702	EC		-	-	92.7
80709	Chemotaxis histidine kinase CheA	8640	EC	3D	1b3qA02	-	93.1
80781	Phosphate regulon sensor protein	8178	EC		-	-	92.1
28276	Sensory histidine kinase BaeS	8097	EC		-	-	59.1
80664	Mlh1 mismatch repair mutL	8009	EC	3D	4p7aA01	-	78.8
63378	Sensor histidine kinase DpiB	6171	EC		-	-	41.8
51731	Sensory histidine kinase UhpB	5321	EC		-	-	25.1
62335	Sensor histidine kinase DcuS	5171	EC		-	-	49.6
41555	Nitrate/nitrite sensor protein NarQ	5016	EC		-	-	36.7
80919	Oxygen sensor histidine kinase NreB	4847	EC		-	-	94.5
80483	Sensor protein qseC	4546	EC	3D	3jz3A01	-	54.1
80838	Serine-protein kinase RsbW	4378	EC		-	-	95.6
80422	Histidine kinase	3889	EC		-	-	51.7
7307	Sensor histidine kinase RcsC	3808	EC		-	-	60.4
20053	Histidine kinase	3642	EC		-	-	22.5
50215	Putative sensor-like histidine kinase YfhK	3593	EC		-	-	18.2
80839	Histidine kinase	3579	EC		-	-	62.8
21647	Histidine kinase	3439	EC		-	-	29.5
80257	Sensor protein kinase walK	2580	EC		-	-	45.6
80675	Probable DNA topoisomerase 2	2207	EC	3D	1zxmA01	-	85.6
80773	Mitochondrial pyruvate dehydrogenase kinase	2079	EC	3D	2btzA02	-	88.8
22477	Histidine kinase	1866	EC		-	-	23.7
49065	Probable sensor kinase SilS	1842	EC		-	-	64.1
80890	Sensor histidine kinase	1811	EC		-	-	95.3
38458	Sensor-like histidine kinase RcsD	1741	EC		-	-	32.5
80498	Sensor histidine kinase GraS	1722	EC		-	-	61.3
80702	Multi-sensor hybrid histidine kinase	1480	EC		-	-	82.8
80732	Mismatch repair endonuclease pms1	1326	EC	3D	1ea6A01	-	85.9
57370	Histidine kinase	1305	EC		-	-	16.1
80688	DNA mismatch repair protein	1168			-	-	92.4
80667	Signal transduction histidine-protein kinase ArlS	985	EC		-	-	63.6
2942	DNA gyrase subunit B	984	EC	3D	3g75A00	-	86.5
80929	Sensory transduction histidine kinase	929	EC		-	-	95.1
80819	DNA gyrase subunit B	792	EC		-	-	85.3
14286	Sensor protein TorS	783	EC		-	-	34.6
80731	DNA topoisomerase VI subunit B	759	EC	3D	1mu5A01	-	92.2
8835	Putative sensor for regulator EvgA	704	EC		-	-	15.1
39601	Histidine kinase	678	EC		-	-	29.6
80993	Heme sensor protein HssS	621	EC		-	-	76.8
23274	Two-component system sensor histidine kinase VanSB	537	EC		-	-	26.8
80290	Molecular chaperone HtpG	530			-	-	77.5
35074	Histidine kinase	476	EC		-	-	28.4
80930	DNA mismatch repair protein Mlh3	475	EC		-	-	93.6
80777	Ubiquitin-associated/translation elongation factor EF1B	453	EC		-	-	94.4
885	DNA topoisomerase large subunit	440	EC		-	-	2.0
80316	Sensor histidine kinase MtrB	383	EC		-	-	33.2
81045	Sensor protein, histidine kinase	317	EC		-	-	95.8
64381	Heme sensor protein HssS	277	EC		-	-	3.9
80413	Histidine kinase	273	EC		-	-	55.3
80822	Oncorhynchus mykiss genomic scaffold, scaffold_3390	266			-	-	80.6
80276	ETR3 ethylene receptor protein	261	EC	3D	4pl9A00	-	89.1
74901	Serine/threonine-protein kinase RsbT	252	EC		-	-	11.5
18446	Histidine kinase	230	EC		-	-	3.7
80459	Sensor histidine kinase RegB	222	EC		-	-	88.5
80795	Autoinducer 2 sensor kinase/phosphatase LuxQ	214	EC		-	-	88.2
80629	DNA mismatch repair protein MutL	210			-	-	22.6
47747	Heavy metal sensor kinase family protein	210	EC		-	-	13.2
80679	Putative phytochrome D	199			-	-	92.0
54546	Histidine kinase	197	EC		-	-	15.5
53817	Sensor histidine kinase	196	EC		-	-	35.4
68178	Signal transduction histidine-protein kinase/phosphatase DegS	195	EC		-	-	18.1
13229	Putative sensor histidine kinase pdtaS	189	EC		-	-	20.7
80764	Histidine kinase	182	EC		-	-	85.4
22015	Histidine protein kinase SaeS	165	EC		-	-	5.9
10052	Histidine kinase	162	EC		-	-	0.0
31811	Histidine kinase	160	EC		-	-	0.8
8524	Histidine kinase	160	EC		-	-	12.6
80517	Sensor-like histidine kinase senX3	157	EC		-	-	42.0
24908	Histidine kinase	149	EC		-	-	13.1
80988	Integral membrane sensor hybrid histidine kinase	142	EC		-	-	82.8
30072	Histidine kinase	139	EC		-	-	12.6
80678	Putative phytochrome A	131			-	-	94.4
68957	Two component sensor histidine kinase DevS	130	EC		-	-	0.0
7813	DNA mismatch repair protein MutL	128			-	-	7.7
80446	Histidine kinase	121	EC		-	-	53.0
44973	Sensor histidine kinase	116	EC		-	-	0.8
71201	Two component sensor kinase	116	EC		-	-	8.4
26329	Sensor protein SrrB	110	EC		-	-	6.7
18544	Multi-sensor signal transduction histidine kinase	110	EC		-	-	3.9
80682	DNA mismatch repair protein MutL	110			-	-	90.6
81059	Blue-light-activated histidine kinase 1	103	EC		-	-	45.9
31806	Uncharacterized sensor-like histidine kinase SAV0224	99	EC		-	-	11.2
62290	Pkp1p	93	EC		-	-	23.2
69015	Histidine kinase	91	EC		-	-	4.3
33500	Uncharacterized sensor-like histidine kinase SERP2405	90	EC		-	-	7.8
62341	Histidine kinase	89	EC		-	-	0.8
80621	Putative sensor histidine kinase	88	EC		-	-	70.2
80972	Sensor histidine kinase YvrG	87	EC		-	-	81.5
54427	Sensor histidine kinase	87	EC		-	-	26.6
16646	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial	86	EC	3D	1gjvA01	-	39.8
62866	Histidine kinase	79	EC		-	-	26.0
35076	Histidine kinase, two component regulatory protein	78	EC		-	-	20.3
80851	Probable C4-dicarboxylate sensor kinase	76	EC		-	-	69.1
72569	Accessory gene regulator C	71	EC	3D	4bxiA00	-	6.7
80860	Sensor protein CitS	70	EC		-	-	69.2
26383	Histidine kinase	69	EC		-	-	43.0
53061	Histidine kinase	68	EC		-	-	0.0
31850	Sensor histidine kinase	63	EC		-	-	11.3
30478	Histidine kinase	63	EC		-	-	1.5
30068	Alginate biosynthesis sensor protein KinB	60	EC		-	-	7.1
23269	DNA mismatch repair protein	59			-	-	14.9
57371	Sensor protein PilS	57	EC		-	-	1.6
52199	Histidine kinase	56	EC		-	-	0.0
80642	Sensor histidine kinase GraS	55	EC		-	-	78.6
35091	Histidine kinase	55	EC		-	-	10.6
56419	Histidine kinase	54	EC		-	-	0.8
10882	Histidine kinase	53	EC		-	-	0.8
62524	Sensor kinase citA, putative	52	EC		-	-	3.4
53888	Histidine kinase	51	EC		-	-	0.0
23339	Signal transduction histidine kinase	50			-	-	5.4
13956	Sensor histidine kinase GraS	49	EC		-	-	19.1
68958	Sensor histidine kinase DesK	48	EC	3D	3ehgA00	-	13.3
80109	Phytochrome C	48			-	-	48.1
1332	DNA mismatch repair protein MLH2	48			-	-	14.6
42266	Sensor protein CseC	47	EC		-	-	41.6
61677	Sporulation kinase B	47	EC		-	-	10.5
66063	Sensor histidine kinase YdfH	46	EC		-	-	31.3
58375	Osmolarity sensor protein envZ	46	EC		-	-	6.9
53178	Histidine kinase	46	EC		-	-	0.8
35092	Histidine kinase	46	EC		-	-	4.0
38283	Histidine kinase	45	EC		-	-	13.7
15376	Cell-division control histidine kinase PdhS	42	EC		-	-	7.6
46372	Alkaline phosphatase synthesis sensor protein PhoR	42	EC		-	-	8.7
80653	Sensor histidine kinase/response regulator Fos-1	41	EC		-	-	71.8
67842	Sensor protein UhpB	40	EC		-	-	9.4
44970	Sensor histidine kinase	38	EC		-	-	4.0
39692	Sensor histidine kinase	37			-	-	13.5
69894	Hypothetical histidine kinase response regulator	37			-	-	0.0
20037	Histidine kinase	37	EC		-	-	0.0
28273	Histidine kinase	35	EC		-	-	1.6
49338	Histidine kinase	31	EC		-	-	4.7
50557	Sensor histidine kinase AruS	31	EC		-	-	4.1
4699	Uncharacterized protein	30	EC		-	-	21.6
39335	Histidine kinase	30	EC		-	-	6.2
31858	Histidine kinase	30	EC		-	-	1.6
69569	Sensor histidine kinase YvfT	28	EC		-	-	6.8
23321	Sensory box sensor histidine kinase/response regulator VieS	28	EC		-	-	1.5
80159	Phytochrome A type 4	28			-	-	38.9
45119	Aerobic respiration control sensor protein	28	EC		-	-	17.1
55987	Histidine kinase	27	EC		-	-	29.1
19220	Sensor histidine kinase	27			-	-	16.8
6105	Histidine kinase	26	EC		-	-	8.3
17547	Histidine kinase	26	EC		-	-	0.0
80330	DNA mismatch repair protein MutL	25			-	-	56.8
13955	DNA mismatch repair protein MutL	25			-	-	2.1
20150	Signal transduction histidine-protein kinase AfsQ2	24	EC		-	-	38.0
58351	Histidine kinase	24	EC		-	-	10.1
40949	Sporulation kinase A	23	EC		-	-	0.0
26335	Sensor histidine kinase YcbM	21	EC		-	-	6.8
69101	Lin0043 protein	20			-	-	0.0
20949	DNA topoisomerase 2	20	EC		-	-	5.8
13496	Histidine kinase	20	EC		-	-	9.1
67127	Sensor protein NarQ homolog	19	EC		-	-	17.0
64058	Two-component sensor histidine kinase NatR	18	EC		-	-	8.3
49044	Sensor histidine kinase	17	EC		-	-	1.8
30071	Sensor protein CutS	16	EC		-	-	0.0
80275	DNA mismatch repair protein MutL	15			-	-	26.0
20948	Histidine protein kinase SaeS	14	EC		-	-	1.4
80520	DNA mismatch repair protein MutL	14			-	-	46.7
47746	Histidine kinase	14	EC		-	-	15.7
80658	Phytochrome-1	14			-	-	49.6
23277	Sensor histidine kinase YclK	13	EC		-	-	0.0
16951	Phytochrome C	13			-	-	35.1
42272	Sensor histidine kinase ComP	13	EC		-	-	5.4
80743	Related to dna mismatch repair homologue Hpms2	11			-	-	47.2
11657	DNA mismatch repair protein MutL	10			-	-	0.0
6765	Histidine protein kinase 1	10	EC		-	-	0.7
80467	Wide host range VirA protein	9	EC		-	-	48.8
80757	Uncharacterized protein	9			-	-	11.0
30073	Sensor protein DivL	9	EC	3D	4q20A02	-	2.1
80232	DNA mismatch repair protein MutL	9			-	-	30.4
73398	Nuclear factor NO VEIN	9			-	-	26.8
61725	Nisin biosynthesis sensor protein NisK	8	EC		-	-	0.8
1706	Protein EIN4	8			-	-	9.8
80432	DNA mismatch repair protein MutL	8			-	-	34.3
1508	DNA gyrase subunit B-like protein MSMEG_0457/MSMEI_0444	7	EC		-	-	8.8
43024	Sensor histidine kinase YfiJ	7	EC		-	-	11.9
21244	Histidine kinase	6	EC		-	-	5.8
10361	Uncharacterized protein	6			-	-	4.2
61081	Heavy metal sensor kinase subfamily protein	6	EC		-	-	38.1
18148	DNA topoisomerase II	6	EC		-	-	21.2
80078	DNA mismatch repair protein MutL	5			-	-	17.0
30065	Sensor protein CzcS	4	EC		-	-	0.0
71649	Putative sensor histidine kinase	4			-	-	0.0
80263	DNA mismatch repair protein MutL	4			-	-	25.8
7249	Gliding motility regulatory protein	4	EC		-	-	0.0
18452	Drug sensory protein A	4	EC		-	-	0.0
80761	Hybrid signal transduction histidine kinase L	3	EC		-	-	48.1
10126	Histidine kinase 5	3	EC		-	-	7.4
80440	DNA mismatch repair protein MutL	3			-	-	12.3
36654	Sensor histidine kinase PmrB	3	EC		-	-	15.1
4092	Uncharacterized protein	3			-	-	13.5
3654	Sensory/regulatory protein RpfC	3	EC		-	-	0.0
10379	Uncharacterized protein	3			-	-	12.0
36729	Sensor histidine kinase/response regulator	3			-	-	14.5
44972	Histidine protein kinase DivJ	3	EC		-	-	15.3
13227	Phytochrome E	2			-	-	6.6
4294	Sensor histidine kinase/response regulator, putative AFU_orthologue AFUA_3G12550	2			-	-	11.2
12608	DNA mismatch repair protein MutL	2			-	-	7.9
80092	Uncharacterized sensor-like histidine kinase ycf26	2	EC		-	-	17.1
80126	DNA mismatch repair protein MutL	2			-	-	18.5
28274	Hybrid signal transduction protein dokA	2			-	-	9.8
79995	PMS2L15 protein	2			-	-	16.0
26327	Autoinducer 1 sensor kinase/phosphatase LuxN	2	EC		-	-	0.0
1941	Ethylene receptor 2	2			-	-	4.0
24063	Uncharacterized sensor-like histidine kinase R01002	2	EC		-	-	9.7
55533	Sensor histidine kinase SpaK	2	EC		-	-	6.4
36643	Sensor protein SphS	1	EC		-	-	0.0
19201	Hybrid signal transduction histidine kinase K	1	EC		-	-	0.0
2710	FAAL093Cp	1			-	-	0.0
33499	Hybrid signal transduction histidine kinase F	1	EC		-	-	0.0
14161	Sensor histidine kinase GlnK	1	EC		-	-	0.0
43589	Peroxide stress-activated histidine kinase mak3	1	EC		-	-	0.0
62291	Sensor histidine kinase YbdK	1	EC		-	-	0.0
26333	Hybrid signal transduction histidine kinase C	1	EC		-	-	0.0
64752	Nitrogen fixation regulatory protein	1			-	-	0.0
72889	Histidine kinase	1	EC		-	-	0.0
43591	Peroxide stress-activated histidine kinase mak1	1	EC		-	-	0.0
4776	DNA mismatch repair protein MutL	1			-	-	0.0
35080	Peroxide stress-activated histidine kinase mak2	1	EC		-	-	0.0
79451	Predicted protein	1			-	-	0.0
80455	DNA mismatch repair protein MutL	1			-	-	0.0
18742	Histidine kinase	1	EC		-	-	0.0
80638	DNA mismatch repair protein MutL	1			-	-	0.0
67832	Putative heat shock protein HSP 90-alpha A4	1			-	-	0.0
70844	Sensor histidine kinase	1			-	-	0.0
11988	DNA mismatch repair protein, putative AFU_orthologue AFUA_8G05820	1			-	-	0.0
49012	Swarming motility regulation sensor protein RssA	1	EC		-	-	0.0
20024	DNA mismatch repair protein MutL	1			-	-	0.0
30066	Protein rIIA	1			-	-	0.0
1942	Hybrid signal transduction histidine kinase D	1	EC		-	-	0.0
65431	Multi-sensor signal transduction histidine kinase	1			-	-	0.0