CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.565 | Heat Shock Protein 90 |
|
3.30.565.10 | Histidine kinase-like ATPase, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Histidine kinase-like ATPase, C-terminal domain |
| Functional Family | Sensor histidine kinase PhoQ |
Enzyme Information
| 3.1.3.- |
Phosphoric monoester hydrolases.
based on mapping to UniProt P23837
|
| 2.7.3.- |
Phosphotransferases with a nitrogenous group as acceptor.
based on mapping to UniProt P23837
|
| 2.7.13.3 |
Histidine kinase.
based on mapping to UniProt P23837
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
-!- This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). -!- A number of histones can act as acceptor.
|
UniProtKB Entries (1)
| P23837 |
PHOQ_ECOLI
Escherichia coli K-12
Sensor protein PhoQ
|
PDB Structure
| PDB | 1ID0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural and mutational analysis of the PhoQ histidine kinase catalytic domain. Insight into the reaction mechanism.
J.Biol.Chem.
|