The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 120976: 3-dehydroquinate dehydratase, type I

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 15 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
3-dehydroquinate dehydratase activity GO:0003855
Catalysis of the reaction: 3-dehydroquinate = 3-dehydroshikimate + H(2)O.
7 P05194 (/IDA) P08566 (/IDA) P24670 (/IDA) P36923 (/IDA) P58687 (/IDA) Q186A6 (/IDA) Q59087 (/IDA)
3-dehydroquinate dehydratase activity GO:0003855
Catalysis of the reaction: 3-dehydroquinate = 3-dehydroshikimate + H(2)O.
3 O84375 (/ISS) P56961 (/ISS) Q9Z6M4 (/ISS)
Shikimate 3-dehydrogenase (NADP+) activity GO:0004764
Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+.
3 O84375 (/ISS) P56961 (/ISS) Q9Z6M4 (/ISS)
NADP binding GO:0050661
Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
3 O84375 (/ISS) P56961 (/ISS) Q9Z6M4 (/ISS)
Shikimate 3-dehydrogenase (NADP+) activity GO:0004764
Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+.
2 P08566 (/IDA) Q9SQT8 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P08566 (/IPI) P63588 (/IPI)
3-dehydroquinate dehydratase activity GO:0003855
Catalysis of the reaction: 3-dehydroquinate = 3-dehydroshikimate + H(2)O.
1 Q5AS44 (/RCA)
3-dehydroquinate synthase activity GO:0003856
Catalysis of the reaction: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate.
1 P08566 (/IDA)
3-dehydroquinate synthase activity GO:0003856
Catalysis of the reaction: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate.
1 Q5AS44 (/RCA)
3-phosphoshikimate 1-carboxyvinyltransferase activity GO:0003866
Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate.
1 P08566 (/IDA)
3-phosphoshikimate 1-carboxyvinyltransferase activity GO:0003866
Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate.
1 Q5AS44 (/RCA)
Shikimate 3-dehydrogenase (NADP+) activity GO:0004764
Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+.
1 Q5AS44 (/RCA)
Shikimate kinase activity GO:0004765
Catalysis of the reaction: ATP + shikimate = 3-phosphoshikimate + ADP + 2 H(+).
1 P08566 (/IDA)
Shikimate kinase activity GO:0004765
Catalysis of the reaction: ATP + shikimate = 3-phosphoshikimate + ADP + 2 H(+).
1 Q5AS44 (/RCA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P05194 (/IDA)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
3,4-dihydroxybenzoate biosynthetic process GO:0046279
The chemical reactions and pathways resulting in the formation of 3,4-dihydroxybenzoate.
6 P05194 (/IDA) P24670 (/IDA) P36923 (/IDA) P58687 (/IDA) Q186A6 (/IDA) Q59087 (/IDA)
Chorismate biosynthetic process GO:0009423
The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds.
3 O84375 (/ISS) P56961 (/ISS) Q9Z6M4 (/ISS)
Shikimate metabolic process GO:0019632
The chemical reactions and pathways involving shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. It is an important intermediate in the biosynthesis of aromatic amino acids.
3 O84375 (/ISS) P56961 (/ISS) Q9Z6M4 (/ISS)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q00784 (/IMP)
Aromatic amino acid family biosynthetic process GO:0009073
The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
1 Q5AS44 (/RCA)
Chorismate biosynthetic process GO:0009423
The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds.
1 Q9P7R0 (/ISO)
Chorismate biosynthetic process GO:0009423
The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds.
1 P08566 (/TAS)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
1 Q9SQT8 (/IMP)
Quinate catabolic process GO:0019631
The chemical reactions and pathways resulting in the breakdown of quinate, the anion of quinic acid.
1 Q00784 (/IMP)
Shikimate metabolic process GO:0019632
The chemical reactions and pathways involving shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. It is an important intermediate in the biosynthesis of aromatic amino acids.
1 Q9SQT8 (/IDA)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P05194 (/IDA) Q9P7R0 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
1 Q9SQT8 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
1 Q9SQT8 (/IDA)