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CATH Superfamily 3.20.20.70

Aldolase class I

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 120976: 3-dehydroquinate dehydratase, type I

There are 6 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
3-dehydroquinate dehydratase. [EC: 4.2.1.10]
3-dehydroquinate = 3-dehydroshikimate + H(2)O.
    		 8154 A0A009GSS9 A0A009GSS9 A0A009GWB4 A0A009GWB4 A0A009HC30 A0A009HC30 A0A009IMH8 A0A009IMH8 A0A009K5N1 A0A009K5N1
    (8144 more...)
    Shikimate dehydrogenase. [EC: 1.1.1.25]
    Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
    • NAD(+) cannot replace NADP(+).
    • In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.
    		 1290 A0A010RP22 A0A010RP22 A0A017PLG1 A0A017PLG1 A0A017S5L2 A0A017S5L2 A0A024RVA1 A0A024RVA1 A0A059J9X2 A0A059J9X2
    (1280 more...)
    3-phosphoshikimate 1-carboxyvinyltransferase. [EC: 2.5.1.19]
    Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O- (1-carboxyvinyl)-3-phosphoshikimate.
      		 1134 A0A010RP22 A0A010RP22 A0A017S5L2 A0A017S5L2 A0A022VZT9 A0A022VZT9 A0A022XQ62 A0A022XQ62 A0A024RVA1 A0A024RVA1
      (1124 more...)
      Shikimate kinase. [EC: 2.7.1.71]
      ATP + shikimate = ADP + shikimate 3-phosphate.
        		 1054 A0A010RP22 A0A010RP22 A0A017S5L2 A0A017S5L2 A0A024RVA1 A0A024RVA1 A0A059J9X2 A0A059J9X2 A0A060S9A7 A0A060S9A7
        (1044 more...)
        3-dehydroquinate synthase. [EC: 4.2.3.4]
        3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate.
        • The hydrogen atoms on C-7 of the substrate are retained on C-2 of the products.
        • Formerly EC 4.6.1.3.
        		 1042 A0A010RP22 A0A010RP22 A0A017S5L2 A0A017S5L2 A0A024RVA1 A0A024RVA1 A0A059J9X2 A0A059J9X2 A0A060S9A7 A0A060S9A7
        (1032 more...)
        Quinate/shikimate dehydrogenase. [EC: 1.1.1.282]
        (1) L-quinate + NAD(P)(+) = 3-dehydroquinate + NAD(P)H. (2) Shikimate + NAD(P)(+) = 3-dehydroshikimate + NAD(P)H.
        • This is the second shikimate dehydrogenase enzyme found in Escherichia coli and differs from EC 1.1.1.25, in that it can use both quinate and shikimate as substrate and either NAD(+) or NADP(+) as acceptor.
        		 4 A0A0L1HU34 A0A0L1HU34 A0A0L1I021 A0A0L1I021
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