The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Topoisomerase I, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
6239
17743
EC
3D
1cy0A02 - 91.7
6140
4366
EC
3D
1d6mA02 - 72.3
6161
780
EC
- - 78.2
6231
441
EC
- - 87.0
3668
192
EC
- - 31.6
6182
154
EC
3D
4cgyA02 - 51.7
6246
106
EC
- - 89.0
6221
98
EC
- - 87.0
6250
45
EC
- - 87.1
6148
10
EC
- - 0.0
6184
8
EC
- - 2.4
6235
3
3D
1gkuB06 - 0.0
6152
2
EC
- - 21.6
3347
2
EC
- - 2.4
6146
1
EC
- - 0.0
6116
1 - - 0.0