CATH Superfamily 3.40.50.1220

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	Electron transfer flavoprotein, alpha subunit	994	3D	1efpC01	-	92.8
2	NAD P	749	3D	1u31B00	-	90.9
3	NAD-dependent protein deacylase 1	573	3D	6eqsD01	-	96.9
10	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	298	3D	5z2uH02	-	25.8
5	NAD-dependent deacetylase sirtuin-2	293	3D	5fyqB01	-	84.4
4	Electron transfer flavoprotein	272		-	-	91.2
8	Acetolactate synthase	264	3D	5wkcE02	-	93.7
6	2-hydroxyacyl-CoA lyase 1	249	3D	2q29B02	-	93.4
7	NAD-dependent histone deacetylase sirtuin-1	222	3D	5btrB02	-	81.9
9	Pyruvate decarboxylase 1	209	3D	2vbiH02	-	97.4
12	NAD-dependent protein deacetylase sirtuin-6	160	3D	6hoyB01	-	66.9
11	NAD-dependent deacetylase sirtuin-7	130		-	-	75.6
13	Pyruvate dehydrogenase [ubiquinone]	125	3D	3eyaL02	-	77.6
14	Acetolactate synthase	109		-	-	25.7
15	NAD-dependent protein deacetylase SRT1	97		-	-	55.9
18	Pyruvate decarboxylase isozyme	94	3D	2w93D02	-	76.3
16	SIR2 family histone deacetylase	88		-	-	87.8
41	NAD-dependent protein deacetylase sirtuin-3, mitochondrial	86	3D	6isoI01	-	27.9
17	NAD-dependent histone deacetylase SIR2	64		-	-	87.7
19	NAD-dependent protein deacetylase sirtuin-1	46		-	-	73.4
20	Nad-dependent histone deacetylase sir2-like protein	45		-	-	90.9
21	IlvB bacterial acetolactate synthase	42		-	-	58.4
22	Electron transfer flavoprotein, alpha subunit	42		-	-	20.2
23	Electron transfer flavoprotein, alpha subunit	41		-	-	28.8
28	Acetolactate synthase, catabolic	40		-	-	75.2
24	2-hydroxyacyl-CoA lyase	40		-	-	54.6
36	NAD-dependent protein deacetylase HST2	29	3D	2qqgA01	-	73.5
83	Pyruvate oxidase	23	3D	2ezuB02	-	0.7
26	NAD-dependent protein deacetylase sirtuin-2	23		-	-	23.4
25	Pyruvate decarboxylase	23		-	-	58.9
27	Unplaced genomic scaffold supercont1.13, whole genome shotgun sequence	22		-	-	70.5
76	N 2 2-carboxyethyl	21	3D	2ihvD02	-	0.0
29	NAD-dependent protein deacetylase sirtuin-6 isoform X2	20		-	-	78.2
32	NAD-dependent protein deacylase	20	3D	3u3dA01	-	12.2
30	Transcriptional regulatory protein sir2b	19		-	-	6.2
31	Alpha-keto acid decarboxylase family protein	18		-	-	6.7
33	Electron transfer flavoprotein subunit alpha	18		-	-	7.8
35	Electron transfer flavoprotein alpha subunit apoprotein	17		-	-	55.4
34	NAD-dependent histone deacetylase HST3	17		-	-	72.1
37	Transcriptional regulatory protein sir2b	16		-	-	0.0
44	NAD-dependent histone deacetylase SIR2	16	3D	4iaoB02	-	43.9
45	Electron transfer flavoprotein subunit alpha, mitochondrial	15	3D	2a1uA02	-	35.8
38	NAD-dependent protein deacetylase sirtuin-6 isoform X2	15		-	-	70.5
39	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	14		-	-	1.0
40	3D- 3,5/4	14		-	-	12.8
43	NAD-dependent protein deacetylase	12		-	-	4.7
42	Alpha-keto-acid decarboxylase	12		-	-	5.9
48	Electron-transfer-flavoprotein, alpha polypeptide, putative	11		-	-	37.2
46	Putative indole-3-pyruvate decarboxylase	11		-	-	8.0
49	Electron transfer flavoprotein alpha subunit	11		-	-	16.0
47	Unplaced genomic scaffold supercont1.7, whole genome shotgun sequence	11		-	-	12.6
50	NAD-dependent deacetylase, Sir2 family protein	11		-	-	63.5
51	Pyruvate decarboxylase, putative	10		-	-	43.2
53	Phenylpyruvate decarboxylase	10		-	-	2.1
52	Putative 2-hydroxyacyl-CoA lyase	10		-	-	45.0
56	Pyruvate decarboxylase, putative	9		-	-	8.0
57	Acetyl-CoA decarbonylase/synthase complex subunit epsilon	9		-	-	23.1
55	Thi3p	9		-	-	9.9
54	Putative acetolactate synthase IlvG	9		-	-	0.0
58	Deacetylase SIR2	8		-	-	3.4
59	NAD-dependent protein deacetylase sirtuin-6 isoform X3	8		-	-	30.6
63	2-oxoglutarate decarboxylase/hydro-lyase/magnesium ion-binding protein	7		-	-	18.3
60	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	7		-	-	0.0
62	NAD-dependent deacetylase sir2E	7		-	-	51.9
61	NAD-dependent protein deacetylase	7		-	-	43.3
91	Branched-chain alpha-ketoacid decarboxylase	6	3D	2vbgB02	-	0.0
67	NAD-dependent histone deacetylase Sir2	6		-	-	3.3
66	NAD-dependent protein deacetylase sir-2.4	6		-	-	25.4
68	Electron transfer flavoprotein subunit alpha	6		-	-	20.2
64	SIR2 family protein	6		-	-	10.0
65	Sir2 family transcriptional regulator putative	6		-	-	6.5
70	Transcriptional regulator, Sir2 family protein	5		-	-	61.9
69	Putative acetolactate synthase large subunit	5		-	-	0.0
73	Nicotinamide nucleotide transhydrogenase	4		-	-	17.8
74	Electron transfer flavoprotein subunit alpha	4		-	-	6.5
72	Hst3p	4		-	-	37.4
75	Related to NAD-dependent histone deacetylase	4		-	-	44.6
71	Putative pyruvate/indole-pyruvate carboxylase	4		-	-	11.0
82	Chromosome 16, whole genome shotgun sequence	3		-	-	47.4
84	Related to NAD-dependent histone deacetylase	3		-	-	0.0
80	Electron transfer flavoprotein subunit alpha, mitochondrial	3		-	-	14.8
81	Formyltransferase/hydrolase complex Fhc subunit B	3		-	-	0.0
77	NAD-dependent deacetylase, Sir2 family protein	3		-	-	9.4
78	Sirtuin type 2	3		-	-	6.7
79	Probable electron transfer flavoprotein alpha subunit	3		-	-	0.9
100	Uncharacterized protein	2		-	-	0.0
102	Uncharacterized protein	2		-	-	40.1
95	Uncharacterized protein	2		-	-	0.0
93	NAD-dependent protein deacylase SIR2rp2	2		-	-	0.0
85	Probable 2-hydroxyacyl-CoA lyase 1	2		-	-	22.9
90	Thiamine diphosphate-binding protein	2		-	-	0.0
92	DHS-like NAD/FAD-binding domain-containing protein	2		-	-	0.0
94	DHS-like NAD/FAD-binding domain-containing protein	2		-	-	0.0
96	Electron transfer flavoprotein alpha subunit	2		-	-	0.0
98	Uncharacterized protein	2		-	-	11.2
87	ADR254Wp	2		-	-	8.7
99	2-hydroxyphytanoyl-CoA lyase, putative	2		-	-	41.9
101	Uncharacterized protein	2		-	-	37.4
88	Acetolactate synthase, large subunit, putative	2		-	-	9.3
86	Sulfoacetaldehyde acetyltransferase	2		-	-	9.2
97	Electron transfer flavoprotein alpha-subunit	2		-	-	0.0
89	Phenylpyruvate decarboxylase	2		-	-	0.7
127	Predicted protein	1		-	-	0.0
120	Sir2-type regulatory transcription factor silent information regulator protein	1		-	-	0.0
107	Uncharacterized protein	1		-	-	0.0
114	Uncharacterized protein	1		-	-	0.0
138	Sirtuin 1	1		-	-	0.0
122	Uncharacterized protein	1		-	-	0.0
130	NAD-dependent deacetylase sir2B	1		-	-	0.0
137	Uncharacterized protein	1		-	-	0.0
132	Uncharacterized protein	1		-	-	0.0
128	Uncharacterized protein	1		-	-	0.0
108	Transcriptional regulator, Sir2 family protein	1		-	-	0.0
110	Histone deacetylase HDAC silent information regulator protein 2 Sir2 sirtuin	1		-	-	0.0
117	Predicted protein	1		-	-	0.0
112	NAD-dependent protein deacetylase	1		-	-	0.0
124	Sir2-type regulatory transcription factor silent information regulator protein	1		-	-	0.0
104	Putative 2-hydroxyacyl-CoA lyase	1		-	-	0.0
118	Uncharacterized protein	1		-	-	0.0
134	Thiamine diphosphate dependent-3-acetyloctanal synthase PigD	1		-	-	0.0
133	Uncharacterized protein	1		-	-	0.0
131	Uncharacterized protein	1		-	-	0.0
115	Uncharacterized protein	1		-	-	0.0
103	ACR211Wp	1		-	-	0.0
123	Transcriptional regulator	1		-	-	0.0
119	Predicted protein	1		-	-	0.0
121	Uncharacterized protein	1		-	-	0.0
116	Uncharacterized protein	1		-	-	0.0
135	Sirtuin 7	1		-	-	0.0
139	Uncharacterized protein	1		-	-	0.0
136	Pyruvate decarboxylase	1		-	-	0.0
113	NAD-dependent histone deacetylase sir2	1		-	-	0.0
105	Putative indolepyruvate decarboxylase, isozyme 1	1		-	-	0.0
125	Uncharacterized protein	1		-	-	0.0
106	Putative pyruvate decarboxylase C3G9.11c	1		-	-	0.0
109	Uncharacterized protein	1		-	-	0.0
126	Uncharacterized protein	1		-	-	0.0
111	Transcriptional regulator, Sir2 family protein	1		-	-	0.0
129	Uncharacterized protein	1		-	-	0.0

Network disruptions

CATH Superfamily 3.40.50.1220

TPP-binding domain

Functional Families

Browse Functional Families