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1 keywords

CATH Domain 5btrB02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.1220 TPP-binding domain

Domain Context

CATH Clusters

Superfamily TPP-binding domain
Functional Family NAD-dependent histone deacetylase sirtuin-1

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt Q96EB6

UniProtKB Entries (1)

Q96EB6
SIR1_HUMAN
Homo sapiens
NAD-dependent protein deacetylase sirtuin-1

PDB Structure

PDB 5BTR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol
Cao, D., Wang, M., Qiu, X., Liu, D., Jiang, H., Yang, N., Xu, R.M.
Genes Dev.
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