The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"HUPs
".
Browse Functional Families
| ID | Function Family (FunFam) Name | Total Sequences | Enzyme? | Structure? | Structural Representative | PDB Sites? | Alignment Diversity (0-100) |
|---|---|---|---|---|---|---|---|
| 88789 | 72287 | 3D |
1jmvA00 | - | 91.0 | ||
| 88283 | 30438 | EC |
3D |
1b6tA00 | - | 92.8 | |
| 88849 | 25167 | EC |
3D |
2derA01 | - | 93.8 | |
| 86425 | 24037 | EC |
3D |
1ffyA01 | - | 86.5 | |
| 61883 | 22873 | - | - | 5.3 | |||
| 18900 | 20236 | EC |
3D |
1li5A01 | - | 83.3 | |
| 86637 | 19969 | EC |
3D |
3zgzA01 | - | 93.8 | |
| 89013 | 19413 | EC |
3D |
2vxoA02 | - | 94.2 | |
| 88792 | 19287 | EC |
3D |
2pidA01 | - | 95.3 | |
| 88968 | 18565 | EC |
3D |
2oq2A00 | - | 97.0 | |
| 86499 | 18449 | EC |
3D |
1f4lA02 | - | 93.5 | |
| 87752 | 18361 | EC |
3D |
3al0C02 | - | 94.9 | |
| 52835 | 17977 | - | - | 37.1 | |||
| 89155 |
3 +
|
17644 | EC |
3D |
1wxeA00 | - | 90.1 |
| 86689 | 17641 | EC |
3D |
3sp1A01 | - | 83.9 | |
| 86404 | 16373 | EC |
- | - | 92.6 | ||
| 89128 | 16225 | EC |
3D |
3op1A01 | - | 91.8 | |
| 89071 | 15187 | EC |
3D |
1k4kA00 | - | 90.6 | |
| 87825 | 15163 | EC |
3D |
1tfuA00 | - | 97.0 | |
| 89168 | 14505 | EC |
3D |
1ct9A02 | - | 91.2 | |
| 87614 | 14386 | EC |
3D |
3sz3A01 | - | 93.3 | |
| 88707 | 14003 | EC |
3D |
1ihoA01 | - | 95.1 | |
| 87272 | 13011 | EC |
3D |
1bs2A01 | - | 86.9 | |
| 89154 | 11769 | EC |
3D |
3bl5A00 | - | 92.0 | |
| 88446 |
Ile
|
11704 | EC |
3D |
1ni5A01 | - | 89.3 |
| 89046 | 11490 | EC |
3D |
3elbA01 | - | 88.8 | |
| 87494 | 11228 | EC |
- | - | 91.1 | ||
| 88842 | 10171 | EC |
3D |
2nz2A01 | - | 96.8 | |
| 88701 | 9833 | EC |
3D |
4h3sA01 | - | 94.8 | |
| 43899 | 9744 | EC |
- | - | 32.4 | ||
| 88798 | 8761 | EC |
3D |
4kr6A02 | - | 97.4 | |
| 89050 |
Asp
|
8552 | EC |
3D |
1nzjA01 | - | 89.6 |
| 86612 | 8190 | EC |
3D |
1ileA01 | - | 90.5 | |
| 87620 | 7378 | EC |
3D |
5tgtA01 | - | 94.0 | |
| 49058 | 6836 | EC |
3D |
3fdxA00 | - | 72.1 | |
| 85808 | 6008 | - | - | 84.3 | |||
| 85169 | 5736 | EC |
- | - | 86.3 | ||
| 84767 | 5605 | - | - | 23.5 | |||
| 86526 | 5587 | EC |
- | - | 87.1 | ||
| 88425 | 5284 | EC |
3D |
1x6vA03 | - | 96.5 | |
| 89152 | 5201 | EC |
- | - | 79.7 | ||
| 88597 | 4390 | EC |
- | - | 91.2 | ||
| 52308 | 4292 | EC |
3D |
4qrdA01 | - | 96.3 | |
| 86196 | 4192 | 3D |
1efvB00 | - | 89.1 | ||
| 86531 | 3993 | EC |
3D |
3c8zA01 | - | 85.3 | |
| 72667 | 3975 | - | - | 2.4 | |||
| 85893 | 3921 | - | - | 56.7 | |||
| 87948 | 3626 | EC |
3D |
2a1tR01 | - | 90.9 | |
| 88721 | 3323 | EC |
3D |
1irxA01 | - | 95.0 | |
| 87801 | 3315 | EC |
3D |
3nd5A00 | - | 92.1 | |
| 87481 | 3259 | EC |
3D |
3fnrA02 | - | 93.2 | |
| 14575 | 2919 | - | - | 18.6 | |||
| 88846 |
Photoreactivation
|
2880 | EC |
3D |
1dnpA01 | - | 96.4 |
| 89137 | 2732 | - | - | 77.2 | |||
| 88403 | 2520 | EC |
3D |
1o5tA01 | - | 80.5 | |
| 86600 | 2393 | EC |
- | - | 84.2 | ||
| 84131 | 2224 | EC |
3D |
1wkbA01 | - | 84.6 | |
| 88725 | 2177 | EC |
3D |
1n3lA01 | - | 90.7 | |
| 89191 | 2056 | EC |
- | - | 97.5 | ||
| 87428 | 1935 | EC |
3D |
4zcpA00 | - | 84.7 | |
| 88437 | 1934 | EC |
3D |
1gzuA00 | - | 83.7 | |
| 88347 | 1923 | EC |
- | - | 94.3 | ||
| 88601 | 1919 | EC |
- | - | 87.3 | ||
| 87579 |
Ile
|
1837 | EC |
- | - | 93.7 | |
| 87735 | 1641 | EC |
- | - | 93.4 | ||
| 89224 |
AFU_orthologue AFUA_6G11040
|
1548 | EC |
3D |
2wsiA00 | - | 77.5 |
| 88713 | 1501 | EC |
- | - | 97.6 | ||
| 87828 | 1185 | EC |
- | - | 93.0 | ||
| 89108 | 1009 | EC |
3D |
1ej2A00 | - | 98.7 | |
| 88982 |
Ile
|
990 | EC |
3D |
1wy5A01 | - | 92.8 |
| 89105 | 980 | EC |
- | - | 86.7 | ||
| 86791 | 950 | EC |
- | - | 85.1 | ||
| 86260 | 895 | EC |
- | - | 25.7 | ||
| 89064 |
Ile
|
892 | EC |
- | - | 95.3 | |
| 89038 | 848 | EC |
- | - | 92.5 | ||
| 85035 | 757 | EC |
- | - | 62.8 | ||
| 83114 | 678 | - | - | 25.8 | |||
| 86361 |
Photolyase-like
|
565 | EC |
3D |
4ct0A01 | - | 93.3 |
| 87378 | 545 | EC |
- | - | 90.1 | ||
| 32357 |
Ile
|
534 | EC |
- | - | 6.2 | |
| 88628 | 528 | EC |
- | - | 86.3 | ||
| 38005 | 497 | EC |
- | - | 67.5 | ||
| 88973 | 483 | EC |
- | - | 92.7 | ||
| 89238 | 472 | EC |
- | - | 95.7 | ||
| 89027 | 462 | - | - | 92.7 | |||
| 88814 | 461 | EC |
- | - | 96.6 | ||
| 89032 | 460 | EC |
- | - | 81.6 | ||
| 86009 | 457 | EC |
3D |
1cozA00 | - | 41.0 | |
| 81269 | 455 | EC |
- | - | 91.3 | ||
| 88529 | 423 | EC |
- | - | 81.7 | ||
| 88617 | 421 | EC |
- | - | 92.1 | ||
| 44338 | 404 | - | - | 12.8 | |||
| 87248 | 400 | - | - | 88.2 | |||
| 88774 | 389 | EC |
- | - | 90.7 | ||
| 45733 | 383 | EC |
- | - | 48.6 | ||
| 87002 | 346 | - | - | 94.8 | |||
| 56679 | 332 | 3D |
1tq8A00 | - | 20.6 | ||
| 88939 | 330 | EC |
3D |
2ijgX01 | - | 92.1 | |
| 88451 |
Ile
|
312 | EC |
- | - | 90.0 | |
| 86049 | 304 | EC |
- | - | 69.0 | ||
| 87802 | 288 | EC |
- | - | 93.1 | ||
| 83586 | 278 | EC |
- | - | 54.3 | ||
| 89048 | 261 | - | - | 88.7 | |||
| 85763 | 260 | EC |
- | - | 84.0 | ||
| 87746 | 251 | EC |
- | - | 89.4 | ||
| 86735 | 244 | EC |
- | - | 50.2 | ||
| 87558 | 240 | - | - | 96.1 | |||
| 88449 | 239 | EC |
3D |
1vlhA00 | - | 94.2 | |
| 87455 | 217 | - | - | 92.6 | |||
| 89010 | 187 | EC |
- | - | 94.8 | ||
| 43558 | 180 | EC |
3D |
1lw7A01 | - | 63.3 | |
| 89087 | 179 | - | - | 91.3 | |||
| 84837 | 159 | EC |
- | - | 17.5 | ||
| 88992 | 158 | EC |
3D |
3do8A00 | - | 91.0 | |
| 88678 | 150 | EC |
- | - | 89.7 | ||
| 51151 | 145 | - | - | 0.8 | |||
| 48391 | 143 | EC |
- | - | 32.5 | ||
| 48961 | 142 | EC |
- | - | 4.4 | ||
| 88726 | 140 | EC |
- | - | 88.1 | ||
| 87989 | 134 | EC |
- | - | 86.8 | ||
| 89121 | 131 | EC |
- | - | 92.3 | ||
| 86627 | 131 | EC |
3D |
1qu3A01 | - | 65.1 | |
| 84605 | 130 | - | - | 11.0 | |||
| 61993 | 121 | EC |
- | - | 18.0 | ||
| 89149 |
Asp
|
120 | EC |
- | - | 95.7 | |
| 80071 | 118 | EC |
- | - | 11.1 | ||
| 87809 | 115 | EC |
- | - | 91.1 | ||
| 86030 | 115 | EC |
- | - | 13.2 | ||
| 47253 | 114 | EC |
- | - | 21.2 | ||
| 88706 | 114 | EC |
- | - | 85.6 | ||
| 86154 | 113 | EC |
- | - | 75.0 | ||
| 49873 | 112 | EC |
- | - | 16.3 | ||
| 87083 | 110 | EC |
3D |
5ekdA01 | - | 73.2 | |
| 27620 |
Ile
|
110 | EC |
- | - | 9.8 | |
| 71105 | 105 | EC |
- | - | 17.4 | ||
| 88551 | 102 | EC |
- | - | 93.2 | ||
| 85801 | 100 | EC |
- | - | 73.4 | ||
| 42931 | 88 | EC |
- | - | 13.2 | ||
| 52135 | 85 | EC |
- | - | 30.3 | ||
| 89166 |
Ile
|
78 | EC |
- | - | 93.7 | |
| 10847 | 77 | EC |
- | - | 29.4 | ||
| 88152 |
Ile
|
77 | EC |
- | - | 78.6 | |
| 88289 | 74 | EC |
- | - | 89.5 | ||
| 86094 | 74 | EC |
- | - | 55.0 | ||
| 84569 |
Ile
|
72 | EC |
- | - | 46.4 | |
| 86269 | 69 | EC |
- | - | 14.6 | ||
| 87791 | 68 | EC |
- | - | 54.3 | ||
| 34875 | 67 | EC |
- | - | 0.0 | ||
| 88513 | 65 | EC |
- | - | 86.9 | ||
| 89103 | 61 | EC |
- | - | 76.2 | ||
| 28335 |
Ile
|
60 | EC |
- | - | 4.4 | |
| 87255 | 60 | EC |
- | - | 67.6 | ||
| 77553 | 59 | - | - | 17.5 | |||
| 26868 |
Ile
|
56 | EC |
- | - | 11.0 | |
| 87520 | 52 | EC |
- | - | 88.4 | ||
| 88350 | 49 | EC |
3D |
3umvA01 | - | 76.4 | |
| 85193 | 48 | EC |
- | - | 22.1 | ||
| 64671 | 47 | EC |
- | - | 33.6 | ||
| 48404 | 44 | EC |
- | - | 3.0 | ||
| 88684 | 43 | EC |
- | - | 92.2 | ||
| 89143 | 43 | EC |
- | - | 88.9 | ||
| 86343 | 43 | EC |
- | - | 59.7 | ||
| 89201 | 42 | - | - | 94.3 | |||
| 40121 | 41 | - | - | 1.7 | |||
| 47356 | 40 | EC |
- | - | 7.1 | ||
| 67090 | 38 | EC |
- | - | 0.0 | ||
| 29343 |
Ile
|
37 | EC |
- | - | 0.6 | |
| 87135 | 37 | EC |
- | - | 50.6 | ||
| 25564 |
Ile
|
37 | EC |
- | - | 3.0 | |
| 37439 |
Ile
|
36 | EC |
- | - | 19.6 | |
| 28171 | 36 | EC |
- | - | 0.0 | ||
| 9043 | 32 | EC |
- | - | 3.2 | ||
| 84975 | 30 | EC |
- | - | 18.8 | ||
| 89156 | 27 | EC |
- | - | 71.6 | ||
| 88001 |
Glutamate--tRNA ligase GluRS
|
26 | EC |
- | - | 45.0 | |
| 87749 | 26 | EC |
- | - | 67.8 | ||
| 65638 | 25 | - | - | 0.0 | |||
| 89035 | 25 | EC |
- | - | 81.0 | ||
| 39192 | 25 | - | - | 0.0 | |||
| 84867 | 24 | EC |
- | - | 12.9 | ||
| 48423 | 24 | EC |
- | - | 21.5 | ||
| 88742 | 24 | EC |
- | - | 82.7 | ||
| 47213 | 24 | 3D |
1efvA02 | - | 48.8 | ||
| 84873 | 24 | - | - | 28.8 | |||
| 53598 | 23 | EC |
- | - | 1.5 | ||
| 88010 | 22 | - | - | 51.5 | |||
| 38815 | 22 | - | - | 14.0 | |||
| 89056 | 21 | EC |
- | - | 31.6 | ||
| 86233 | 20 | EC |
- | - | 57.8 | ||
| 86137 | 19 | EC |
- | - | 39.1 | ||
| 63045 | 19 | EC |
- | - | 11.5 | ||
| 46561 | 18 | EC |
- | - | 16.9 | ||
| 71945 | 18 | EC |
- | - | 2.7 | ||
| 84833 | 18 | - | - | 24.6 | |||
| 84794 |
Ile
|
18 | EC |
- | - | 22.2 | |
| 84553 | 17 | - | - | 50.5 | |||
| 88366 | 17 | EC |
- | - | 62.3 | ||
| 89139 | 17 | EC |
- | - | 0.0 | ||
| 13670 | 16 | - | - | 0.0 | |||
| 86569 | 16 | EC |
3D |
1pg0A01 | - | 72.7 | |
| 65648 | 15 | EC |
- | - | 3.5 | ||
| 88978 | 15 | EC |
- | - | 68.9 | ||
| 60255 | 13 | - | - | 18.6 | |||
| 47327 | 13 | EC |
- | - | 16.2 | ||
| 63037 | 13 | - | - | 28.6 | |||
| 89131 |
Asp
|
12 | - | - | 16.4 | ||
| 85930 | 12 | - | - | 37.7 | |||
| 86252 | 11 | EC |
- | - | 36.4 | ||
| 84698 | 11 | - | - | 28.2 | |||
| 84961 |
Ile
|
11 | EC |
- | - | 29.3 | |
| 21222 | 11 | EC |
- | - | 5.8 | ||
| 85588 | 10 | EC |
- | - | 21.2 | ||
| 85746 | 10 | - | - | 20.1 | |||
| 59449 | 10 | EC |
- | - | 28.8 | ||
| 45333 | 10 | - | - | 12.9 | |||
| 88439 | 10 | EC |
- | - | 33.4 | ||
| 45357 | 10 | EC |
- | - | 16.3 | ||
| 49737 | 10 | - | - | 15.8 | |||
| 88125 | 10 | - | - | 28.1 | |||
| 42877 |
Ile
|
9 | EC |
- | - | 0.0 | |
| 41116 |
Ile
|
9 | EC |
- | - | 3.0 | |
| 16782 | 9 | EC |
- | - | 17.9 | ||
| 88599 | 9 | EC |
- | - | 62.8 | ||
| 10335 | 9 | EC |
- | - | 0.0 | ||
| 89198 | 8 | EC |
- | - | 58.1 | ||
| 65640 | 8 | - | - | 1.9 | |||
| 51973 | 8 | - | - | 10.1 | |||
| 46572 | 8 | EC |
- | - | 7.9 | ||
| 31122 | 8 | - | - | 29.5 | |||
| 88685 | 8 | EC |
- | - | 71.2 | ||
| 89135 | 7 | EC |
- | - | 49.6 | ||
| 52780 | 7 | 3D |
1np7A01 | - | 3.2 | ||
| 88918 | 7 | EC |
- | - | 28.2 | ||
| 63647 | 7 | - | - | 16.9 | |||
| 87446 | 7 | EC |
- | - | 14.5 | ||
| 88371 | 7 | EC |
- | - | 13.8 | ||
| 63483 | 7 | EC |
- | - | 19.4 | ||
| 39374 | 6 | - | - | 2.1 | |||
| 49879 | 6 | EC |
- | - | 27.2 | ||
| 51567 | 6 | EC |
- | - | 11.5 | ||
| 52330 | 6 | - | - | 11.2 | |||
| 87459 | 6 | EC |
- | - | 62.3 | ||
| 32510 | 6 | - | - | 3.0 | |||
| 47954 | 6 | EC |
- | - | 3.9 | ||
| 35824 | 6 | - | - | 14.8 | |||
| 88959 |
Asp
|
6 | - | - | 54.9 | ||
| 48426 | 6 | EC |
- | - | 2.8 | ||
| 45104 | 6 | EC |
- | - | 5.5 | ||
| 88611 | 6 | EC |
- | - | 48.1 | ||
| 3802 | 5 | EC |
- | - | 26.6 | ||
| 47462 | 5 | - | - | 14.3 | |||
| 88191 |
Ile
|
5 | EC |
- | - | 44.2 | |
| 89074 | 5 | - | - | 69.9 | |||
| 47322 | 5 | - | - | 3.3 | |||
| 85975 | 5 | EC |
- | - | 11.2 | ||
| 52010 | 5 | - | - | 9.1 | |||
| 76419 | 5 | EC |
- | - | 19.0 | ||
| 88905 | 5 | EC |
- | - | 29.9 | ||
| 89031 | 4 | EC |
- | - | 51.9 | ||
| 49855 | 4 | EC |
- | - | 0.0 | ||
| 52777 | 4 | - | - | 0.0 | |||
| 88386 | 4 | EC |
- | - | 33.4 | ||
| 32362 |
Ile
|
4 | EC |
- | - | 10.7 | |
| 37159 |
Ile
|
4 | EC |
- | - | 0.0 | |
| 88607 | 4 | EC |
- | - | 43.7 | ||
| 85795 |
Ile
|
4 | EC |
- | - | 23.5 | |
| 87174 | 3 | - | - | 23.2 | |||
| 46937 | 3 | 3D |
1mjhA00 | - | 0.0 | ||
| 86042 | 3 | EC |
- | - | 12.1 | ||
| 43207 | 3 | - | - | 6.0 | |||
| 86047 | 3 | EC |
- | - | 0.0 | ||
| 54757 | 3 | - | - | 4.0 | |||
| 88777 | 3 | EC |
- | - | 67.4 | ||
| 48934 | 3 | EC |
- | - | 4.6 | ||
| 63321 | 3 | - | - | 9.5 | |||
| 45332 | 3 | - | - | 17.5 | |||
| 88626 | 3 | EC |
- | - | 24.8 | ||
| 12826 |
Glutamine-hydrolyzing
|
3 | EC |
- | - | 26.5 | |
| 35893 | 3 | EC |
- | - | 9.9 | ||
| 87077 | 3 | EC |
- | - | 21.0 | ||
| 45140 | 3 | - | - | 10.2 | |||
| 52783 | 3 | EC |
- | - | 3.6 | ||
| 53117 | 3 | - | - | 0.0 | |||
| 45069 | 3 | EC |
- | - | 6.1 | ||
| 88829 |
Ile
|
2 | EC |
- | - | 37.3 | |
| 60333 | 2 | - | - | 4.2 | |||
| 32638 |
AFU_orthologue AFUA_4G05940
|
2 | - | - | 0.0 | ||
| 42547 | 2 | EC |
- | - | 4.5 | ||
| 85647 | 2 | EC |
- | - | 20.8 | ||
| 13452 | 2 | - | - | 8.0 | |||
| 62440 | 2 | - | - | 1.4 | |||
| 40503 | 2 | EC |
- | - | 7.1 | ||
| 87078 | 2 | EC |
- | - | 22.8 | ||
| 47397 | 2 | - | - | 7.3 | |||
| 88036 | 2 | EC |
- | - | 38.1 | ||
| 28751 | 2 | EC |
- | - | 8.3 | ||
| 56669 | 2 | EC |
- | - | 0.0 | ||
| 17303 | 2 | EC |
- | - | 6.7 | ||
| 62885 | 2 | - | - | 11.0 | |||
| 39598 |
Ile
|
2 | EC |
- | - | 5.5 | |
| 88884 |
Ile
|
2 | EC |
- | - | 37.3 | |
| 54204 | 2 | EC |
- | - | 2.6 | ||
| 44869 | 2 | - | - | 2.1 | |||
| 70231 | 2 | EC |
- | - | 0.0 | ||
| 29142 | 1 | - | - | 0.0 | |||
| 88750 | 1 | EC |
- | - | 0.0 | ||
| 80727 |
Ile
|
1 | EC |
- | - | 0.0 | |
| 36765 | 1 | - | - | 0.0 | |||
| 85920 | 1 | EC |
- | - | 0.0 | ||
| 50446 | 1 | - | - | 0.0 | |||
| 57791 | 1 | - | - | 0.0 | |||
| 54053 | 1 | - | - | 0.0 | |||
| 12846 | 1 | - | - | 0.0 | |||
| 51142 | 1 | - | - | 0.0 | |||
| 51578 | 1 | EC |
- | - | 0.0 | ||
| 46159 | 1 | - | - | 0.0 | |||
| 52478 |
Tyrosine--tRNA ligase Tyrrs AFU_orthologue AFUA_4G08320
|
1 | EC |
- | - | 0.0 | |
| 36760 |
Ile
|
1 | EC |
- | - | 0.0 | |
| 60231 | 1 | - | - | 0.0 | |||
| 88204 | 1 | EC |
- | - | 0.0 | ||
| 17407 | 1 | EC |
- | - | 0.0 | ||
| 88392 | 1 | EC |
- | - | 0.0 | ||
| 22680 |
Ile
|
1 | EC |
- | - | 0.0 | |
| 55549 | 1 | - | - | 0.0 | |||
| 88109 | 1 | EC |
- | - | 0.0 | ||
| 66143 | 1 | - | - | 0.0 | |||
| 61734 | 1 | EC |
- | - | 0.0 | ||
| 52405 | 1 | - | - | 0.0 | |||
| 61737 | 1 | - | - | 0.0 | |||
| 52772 | 1 | EC |
- | - | 0.0 | ||
| 61732 | 1 | EC |
- | - | 0.0 | ||
| 88141 | 1 | EC |
- | - | 0.0 | ||
| 65643 | 1 | - | - | 0.0 | |||
| 59374 | 1 | - | - | 0.0 | |||
| 50296 | 1 | EC |
- | - | 0.0 | ||
| 61019 | 1 | EC |
- | - | 0.0 | ||
| 52776 | 1 | - | - | ||||
| 79310 | 1 | - | - | 0.0 | |||
| 17740 | 1 | EC |
- | - | 0.0 | ||
| 18095 |
Ile
|
1 | EC |
- | - | 0.0 | |
| 27180 | 1 | - | - | 0.0 | |||
| 87918 | - | - | |||||
| 88216 | - | - | |||||
| 80441 | - | - | |||||
| 89141 | - | - |
