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1 keywords

CATH Domain 1o5tA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.620 HUPs

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family Tryptophanyl-tRNA synthetase, putative, expressed

Enzyme Information

6.1.1.2
Tryptophan--tRNA ligase.
based on mapping to UniProt P23381
ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl- tRNA(Trp).

UniProtKB Entries (1)

P23381
SYWC_HUMAN
Homo sapiens
Tryptophan--tRNA ligase, cytoplasmic

PDB Structure

PDB 1O5T
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of Human Tryptophanyl-tRNA Synthetase Catalytic Fragment
Yu, Y., Liu, Y., Shen, N., Xu, X., Xu, F., Jia, J., Jin, Y., Arnold, E., Ding, J.
J.BIOL.CHEM.
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