CATH Domain 1vh5A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.129	Thiol Ester Dehydrase; Chain A
	3.10.129.10	Hotdog Thioesterase

Domain Context

CATH Clusters

Superfamily	Hotdog Thioesterase
Functional Family	1,4-dihydroxy-2-naphthoyl-CoA hydrolase

Enzyme Information

3.1.2.28

1,4-dihydroxy-2-naphthoyl-CoA hydrolase.

based on mapping to UniProt P77781

1,4-dihydroxy-2-naphthoyl-CoA + H(2)O = 1,4-dihydroxy-2-naphthoate + CoA.

-!- This enzyme participates in the synthesis of menaquinones, phylloquinone, as well as several plant pigments. -!- The enzyme from the cyanobacterium Synechocystis sp. PCC 6803 does not accept benzoyl-CoA or phenylacetyl-CoA as substrates. -!- Formerly EC 3.1.2.n1.

UniProtKB Entries (1)

P77781

MENI_ECOLI

Escherichia coli K-12

1,4-dihydroxy-2-naphthoyl-CoA hydrolase

PDB Structure

PDB	1VH5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural analysis of a set of proteins resulting from a bacterial genomics project Badger, J., Sauder, J.M., Adams, J.M., Antonysamy, S., Bain, K., Bergseid, M.G., Buchanan, S.G., Buchanan, M.D., Batiyenko, Y., Christopher, J.A., Emtage, S., Eroshkina, A., Feil, I., Furlong, E.B., Gajiwala, K.S., Gao, X., He, D., Hendle, J., Huber, A., Hoda, K., Kearins, P., Kissinger, C., Laubert, B., Lewis, H.A., Lin, J., Loomis, K., Lorimer, D., Louie, G., Maletic, M., Marsh, C.D., Miller, I., Molinari, J., Muller-Dieckmann, H.J., Newman, J.M., Noland, B.W., Pagarigan, B., Park, F., Peat, T.S., Post, K.W., Radojicic, S., Ramos, A., Romero, R., Rutter, M.E., Sanderson, W.E., Schwinn, K.D., Tresser, J., Winhoven, J., Wright, T.A., Wu, L., Xu, J., Harris, T.J. Proteins