The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Helix-loop-helix DNA-binding domain
".
FunFam 105: Rtg3p
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
6 | P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
6 | P38165 (/IMP) P38165 (/IMP) P38165 (/IMP) P38165 (/IMP) P38165 (/IMP) P38165 (/IMP) |
|
RNA polymerase II transcription factor binding GO:0001085
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II.
|
6 | P38165 (/IPI) P38165 (/IPI) P38165 (/IPI) P38165 (/IPI) P38165 (/IPI) P38165 (/IPI) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | P38165 (/IPI) P38165 (/IPI) P38165 (/IPI) P38165 (/IPI) P38165 (/IPI) P38165 (/IPI) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
6 | P38165 (/HDA) P38165 (/HDA) P38165 (/HDA) P38165 (/HDA) P38165 (/HDA) P38165 (/HDA) |
|
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
1 | A0A1D8PF20 (/IDA) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
7 | A0A1D8PF20 (/IDA) P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) |
|
Autophagy of mitochondrion GO:0000422
The autophagic process in which mitochondria are delivered to the vacuole and degraded in response to changing cellular conditions.
|
6 | P38165 (/IMP) P38165 (/IMP) P38165 (/IMP) P38165 (/IMP) P38165 (/IMP) P38165 (/IMP) |
|
Mitochondria-nucleus signaling pathway GO:0031930
A series of molecular signals that forms a pathway of communication from the mitochondria to the nucleus and initiates cellular changes in response to changes in mitochondrial function.
|
6 | P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
6 | P38165 (/IMP) P38165 (/IMP) P38165 (/IMP) P38165 (/IMP) P38165 (/IMP) P38165 (/IMP) |
|
Cellular response to oleic acid GO:0071400
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus.
|
6 | P38165 (/IMP) P38165 (/IMP) P38165 (/IMP) P38165 (/IMP) P38165 (/IMP) P38165 (/IMP) |
|
Positive regulation of transcription from RNA polymerase II promoter by galactose GO:0000435
Any process involving galactose that activates or increases the rate of transcription from an RNA polymerase II promoter.
|
1 | A0A1D8PF20 (/IMP) |
|
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
|
1 | A0A1D8PF20 (/IMP) |
|
Galactose catabolic process GO:0019388
The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose.
|
1 | A0A1D8PF20 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
7 | A0A1D8PF20 (/IDA) P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
6 | P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) P38165 (/IDA) |