The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Nucleoside Triphosphate Pyrophosphohydrolase
".
FunFam 14: 8-oxo-dGTP diphosphatase MutT
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
42 |
P08337 (/IPI)
P08337 (/IPI)
P08337 (/IPI)
P08337 (/IPI)
P08337 (/IPI)
P08337 (/IPI)
P08337 (/IPI)
P08337 (/IPI)
P08337 (/IPI)
P08337 (/IPI)
(32 more) |
|
Hydrolase activity GO:0016787
Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
|
27 |
P77788 (/IDA)
P77788 (/IDA)
P77788 (/IDA)
P77788 (/IDA)
P77788 (/IDA)
P77788 (/IDA)
P77788 (/IDA)
P77788 (/IDA)
P77788 (/IDA)
P77788 (/IDA)
(17 more) |
|
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
20 |
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
(10 more) |
|
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity GO:0008413
Catalysis of the reaction: 8-oxo-7,8-dihydroguanosine triphosphate = 8-oxo-7,8-dihydroguanosine phosphate + diphosphate. 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for transcription.
|
20 |
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
(10 more) |
|
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
|
20 |
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
(10 more) |
|
8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity GO:0035539
Catalysis of the reaction: 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate + H2O = 8-oxo-7,8-dihydrodeoxyguanosine phosphate + diphosphate. 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate, or 8-oxo-dGTP, is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for DNA synthesis causing transversion mutations. 8-oxo-dGTPase hydrolyses 8-oxo-dGTP to its monophosphate form to prevent the misincorporation of 8-oxo-dGTP into cellular DNA.
|
20 |
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
(10 more) |
|
8-oxo-dGDP phosphatase activity GO:0044715
Catalysis of the reaction 8-oxo-dGDP + H2O = 8-oxo-dGMP + phosphate.
|
20 |
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
(10 more) |
|
8-oxo-GDP phosphatase activity GO:0044716
Catalysis of the reaction 8-oxo-GDP + H2O = 8-oxo-GMP + phosphate.
|
20 |
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
P08337 (/IDA)
(10 more) |
|
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity GO:0008413
Catalysis of the reaction: 8-oxo-7,8-dihydroguanosine triphosphate = 8-oxo-7,8-dihydroguanosine phosphate + diphosphate. 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for transcription.
|
11 |
Q5LWL5 (/ISS)
Q8EJQ2 (/ISS)
Q9KPH6 (/ISS)
Q9KPH6 (/ISS)
Q9KPH6 (/ISS)
Q9KPH6 (/ISS)
Q9KPH6 (/ISS)
Q9KPH6 (/ISS)
Q9KPH6 (/ISS)
Q9KPH6 (/ISS)
(1 more) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | Q6MPX4 (/IPI) Q6MPX4 (/IPI) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
|
27 |
P77788 (/IDA)
P77788 (/IDA)
P77788 (/IDA)
P77788 (/IDA)
P77788 (/IDA)
P77788 (/IDA)
P77788 (/IDA)
P77788 (/IDA)
P77788 (/IDA)
P77788 (/IDA)
(17 more) |
|
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
|
20 |
P08337 (/IC)
P08337 (/IC)
P08337 (/IC)
P08337 (/IC)
P08337 (/IC)
P08337 (/IC)
P08337 (/IC)
P08337 (/IC)
P08337 (/IC)
P08337 (/IC)
(10 more) |
|
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
|
11 |
Q5LWL5 (/ISS)
Q8EJQ2 (/ISS)
Q9KPH6 (/ISS)
Q9KPH6 (/ISS)
Q9KPH6 (/ISS)
Q9KPH6 (/ISS)
Q9KPH6 (/ISS)
Q9KPH6 (/ISS)
Q9KPH6 (/ISS)
Q9KPH6 (/ISS)
(1 more) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.