The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Amidase signature (AS) domain
".
FunFam 1: Fatty-acid amide hydrolase 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 26 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Acylglycerol lipase activity GO:0047372
Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.
|
3 | O00519 (/ISS) O08914 (/ISS) Q9TUI8 (/ISS) |
|
Anandamide amidohydrolase activity GO:0103073
Catalysis of the reaction: anandamide + H2O <=> arachidonate + ethanolaminium(1+)
|
3 | O00519 (/ISS) O08914 (/ISS) Q9TUI8 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | O00519 (/IPI) P97612 (/IPI) |
|
Fatty acid amide hydrolase activity GO:0017064
Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid.
|
2 | O00519 (/IDA) P97612 (/IDA) |
|
Fatty acid amide hydrolase activity GO:0017064
Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid.
|
2 | O08914 (/ISS) Q9TUI8 (/ISS) |
|
Amidase activity GO:0004040
Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3.
|
1 | P97612 (/IDA) |
|
Amidase activity GO:0004040
Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3.
|
1 | O08914 (/ISO) |
|
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
|
1 | P97612 (/IMP) |
|
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
|
1 | O08914 (/ISO) |
|
Lipid binding GO:0008289
Interacting selectively and non-covalently with a lipid.
|
1 | P97612 (/IDA) |
|
Lipid binding GO:0008289
Interacting selectively and non-covalently with a lipid.
|
1 | O08914 (/ISO) |
|
Hydrolase activity, acting on ester bonds GO:0016788
Catalysis of the hydrolysis of any ester bond.
|
1 | P97612 (/IDA) |
|
Hydrolase activity, acting on ester bonds GO:0016788
Catalysis of the hydrolysis of any ester bond.
|
1 | O08914 (/ISO) |
|
Fatty acid amide hydrolase activity GO:0017064
Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid.
|
1 | P97612 (/IMP) |
|
Fatty acid amide hydrolase activity GO:0017064
Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid.
|
1 | O08914 (/ISO) |
|
Fatty acid amide hydrolase activity GO:0017064
Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid.
|
1 | O00519 (/TAS) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | P97612 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | O08914 (/ISO) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P97612 (/IDA) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P97612 (/IMP) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | O08914 (/ISO) |
|
Acylglycerol lipase activity GO:0047372
Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.
|
1 | P97612 (/IDA) |
|
Acylglycerol lipase activity GO:0047372
Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.
|
1 | O08914 (/IMP) |
|
Acylglycerol lipase activity GO:0047372
Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.
|
1 | O08914 (/ISO) |
|
Anandamide amidohydrolase activity GO:0103073
Catalysis of the reaction: anandamide + H2O <=> arachidonate + ethanolaminium(1+)
|
1 | P97612 (/IDA) |
|
Anandamide amidohydrolase activity GO:0103073
Catalysis of the reaction: anandamide + H2O <=> arachidonate + ethanolaminium(1+)
|
1 | O08914 (/ISO) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Monoacylglycerol catabolic process GO:0052651
The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.
|
3 | O00519 (/ISS) O08914 (/ISS) Q9TUI8 (/ISS) |
|
Fatty acid catabolic process GO:0009062
The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
|
2 | O00519 (/IDA) P97612 (/IDA) |
|
Fatty acid catabolic process GO:0009062
The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
|
2 | O08914 (/ISS) Q9TUI8 (/ISS) |
|
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
|
1 | P97612 (/IMP) |
|
Fatty acid catabolic process GO:0009062
The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
|
1 | O08914 (/ISO) |
|
Arachidonic acid metabolic process GO:0019369
The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
|
1 | O00519 (/TAS) |
|
Positive regulation of axon regeneration GO:0048680
Any process that activates, maintains or increases the rate of axon regeneration.
|
1 | Q17449 (/IMP) |
|
Monoacylglycerol catabolic process GO:0052651
The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.
|
1 | P97612 (/IDA) |
|
Negative regulation of blood vessel diameter GO:0097756
Any process that decreases the diameter of blood vessels.
|
1 | P97612 (/IMP) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Organelle membrane GO:0031090
A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.
|
3 | O00519 (/ISS) O08914 (/ISS) Q9TUI8 (/ISS) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
1 | O00519 (/TAS) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | P97612 (/IC) |
|
Organelle membrane GO:0031090
A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.
|
1 | P97612 (/IDA) |
|
Organelle membrane GO:0031090
A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.
|
1 | O08914 (/ISO) |