View in Gene3D

CATH Superfamily 3.90.1300.10

Amidase signature (AS) domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Amidase signature (AS) domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1: Fatty-acid amide hydrolase 1

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Fatty acid amide hydrolase. [EC: 3.5.1.99]
(1) Anandamide + H(2)O = arachidonic acid + ethanolamine. (2) Oleamide + H(2)O = oleic acid + NH(3).
  • Integral membrane protein, the enzyme is responsible for the catabolism of neuromodulatory fatty acid amides, including anandamide and oleamide, occurs in mammalia.
  • Formerly EC 3.5.1.n2.
 5 O00519 O08914 P97612 Q17449 Q9TUI8