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CATH Superfamily 3.90.1150.10

Aspartate Aminotransferase, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aspartate Aminotransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: Succinylornithine transaminase

There are 7 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Succinylornithine transaminase. [EC: 2.6.1.81]
N(2)-succinyl-L-ornithine + 2-oxoglutarate = N-succinyl-L-glutamate 5-semialdehyde + L-glutamate.
  • Also acts on N(2)-acetyl-L-ornithine and L-ornithine, but more slowly.
  • In Pseudomonas aeruginosa, the arginine-inducible succinylornithine transaminase, EC 2.6.1.11 and EC 2.6.1.13 activities are catalyzed by the same enzyme, but this is not the case in all species.
  • This is the third enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine.
  • This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA.
  • The five enzymes involved in this pathway are EC 2.3.1.109, EC 3.5.3.23, EC 2.6.1.81, EC 1.2.1.71 and EC 3.5.1.96.
 4376 A0A029HYL6 A0A029HYL6 A0A029HYL6 A0A029HYL6 A0A029HYL6 A0A029HYL6 A0A029HYL6 A0A029HYL6 A0A029HYL6 A0A029HYL6
(4366 more...)
Acetylornithine transaminase. [EC: 2.6.1.11]
N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.
  • Also acts on L-ornithine and N(2)-succinyl-L-ornithine.
 2766 A0A028APE7 A0A028APE7 A0A028APE7 A0A028APE7 A0A028APE7 A0A028APE7 A0A028APE7 A0A028APE7 A0A028APE7 A0A028APE7
(2756 more...)
Succinyldiaminopimelate transaminase. [EC: 2.6.1.17]
N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2- L-amino-6-oxoheptanedioate + L-glutamate.
    		 2636 A0A028APE7 A0A028APE7 A0A028APE7 A0A028APE7 A0A028APE7 A0A028APE7 A0A028APE7 A0A028APE7 A0A028APE7 A0A028APE7
    (2626 more...)
    Alanine--glyoxylate transaminase. [EC: 2.6.1.44]
    L-alanine + glyoxylate = pyruvate + glycine.
    • With one component of the animal enzyme, 2-oxobutanoate can replace glyoxylate.
    • A second component also catalyzes the reaction of EC 2.6.1.51.
    		 13 Q0WUN0 Q0WUN0 Q0WWF1 Q0WWF1 Q17QF0 Q3UEG6 Q5RFA3 Q64565 Q940M2 Q940M2
    (3 more...)
    (R)-3-amino-2-methylpropionate--pyruvate transaminase. [EC: 2.6.1.40]
    (R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine.
    • The two enantiomers of the 2-methyl-3-oxopropanoate formed by the enzyme interconvert by enolization, so that this enzyme, together with EC 2.6.1.22, provide a route for interconversion of the enantiomers of 3-amino-2-methylpropanoate.
    • Formerly EC 2.6.1.61.
    		 5 Q17QF0 Q3UEG6 Q5RFA3 Q64565 Q9BYV1
    Ethanolamine-phosphate phospho-lyase. [EC: 4.2.3.2]
    Ethanolamine phosphate + H(2)O = acetaldehyde + NH(3) + phosphate.
    • Also acts on D- (or L)-1-aminopropan-2-ol O-phosphate.
    • Formerly EC 4.2.99.7.
    		 4 Q5E9S4 Q7SY54 Q8BWU8 Q8TBG4
    5-phosphonooxy-L-lysine phospho-lyase. [EC: 4.2.3.134]
    (5R)-5-phosphonooxy-L-lysine + H(2)O = (S)-2-amino-6-oxohexanoate + NH(3) + phosphate.
    • Has no activity with phosphoethanolamine (cf. EC 4.2.3.2).
    		 2 Q8IUZ5 Q8R1K4