The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aspartate Aminotransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
1201
3D
1yaaD01 - 97.7
2
1119
3D
5usrC01 - 76.3
3
851
3D
3g8mA02 - 96.9
6
788
3D
6czzD02 - 95.3
5
760
3D
1ejiD01 - 95.2
4
756
3D
1fc4B02 - 93.7
8
658
3D
5eigH02 - 94.3
7
decarboxylating
597 - - 87.0
9
556
3D
4adeB01 - 95.3
10
496 - - 99.1
11
446
3D
4cvqB01 - 62.6
12
364
3D
5hdmB01 - 97.1
13
324
3D
1ibjC02 - 86.6
14
decarboxylating
313 - - 95.2
27
296
3D
3du4B01 - 99.2
22
294
3D
1szuD01 - 96.3
16
290
3D
3n75E03 - 72.4
15
283
3D
2x5dD01 - 57.3
18
276
3D
3rchB03 - 96.0
21
271
3D
5verB01 - 93.2
20
268
3D
4q6rB02 - 95.6
17
261 - - 91.4
19
259 - - 94.8
24
246
3D
3pdbD01 - 80.1
33
245
3D
3ndnD02 - 95.1
35
232
3D
1s0aB01 - 92.7
23
220
3D
2v1pA01 - 44.9
26
210
3D
1u08B01 - 87.8
25
207 - - 97.7
28
194
3D
4uoyA01 - 37.7
29
190 - - 85.9
30
190
3D
1mdzA02 - 97.5
31
170
3D
2z9xB01 - 93.8
32
162
3D
1ordB03 - 75.4
34
154
3D
1jf9A01 - 22.6
41
140
3D
2fm1D02 - 95.2
39
138
3D
3islB01 - 93.6
36
134
3D
2g6wA01 - 47.1
38
132
3D
1iayA01 - 86.3
37
128
3D
3b46B01 - 81.6
40
126
3D
3pdxA01 - 93.3
44
126
3D
3wlxB02 - 71.7
42
125
3D
1ijiA02 - 79.5
54
124
3D
1vp4B01 - 96.5
43
117 - - 89.7
47
116
3D
3ntjD01 - 80.9
45
113 - - 62.6
46
111
3D
2ordB01 - 92.2
55
101
3D
5ft8O01 - 20.3
52
100
3D
3wzfA01 - 57.6
61
99
3D
4zahH02 - 59.3
49
93
3D
2bkwA01 - 89.3
48
93 - - 77.6
50
91 - - 74.1
58
90
3D
4itxB02 - 75.8
62
89
3D
6f5vD01 - 92.0
53
89
3D
4isyD01 - 69.4
51
88 - - 78.9
57
87
3D
2eh6B01 - 90.2
56
81
3D
3e9kA01 - 67.2
65
77
3D
3gzdD01 - 91.9
59
decarboxylating
76 - - 41.7
60
75 - - 38.6
63
67 - - 91.3
64
65 - - 55.7
66
56 - - 86.2
82
55
3D
2yhkB01 - 24.5
85
55
3D
3eibB01 - 85.1
68
54
3D
3bcxB02 - 93.3
67
53 - - 5.6
69
50
3D
5vyeD01 - 55.8
72
48
3D
4wxgC01 - 77.2
191
47
3D
6b6gD01 - 31.2
166
44
3D
5tf5B03 - 92.6
71
41 - - 93.0
76
41
3D
4q76B01 - 81.2
70
41 - - 77.6
136
39
3D
4uqvL02 - 73.2
73
39 - - 68.0
74
38 - - 37.0
77
37 - - 92.1
78
37
3D
1qz9A01 - 78.8
75
37 - - 79.2
84
36
3D
3vomB02 - 52.4
90
36
3D
4a0rB02 - 53.5
79
35 - - 90.2
393
34
3D
5og0A01 - 43.7
80
34 - - 87.5
83
33 - - 81.2
81
33 - - 41.2
86
31 - - 82.8
87
30 - - 80.0
141
30
3D
4wp0D01 - 19.6
89
29 - - 96.1
88
29 - - 95.1
94
26 - - 74.5
93
26 - - 12.3
91
26 - - 83.7
92
26 - - 91.1
96
25 - - 98.3
103
25
3D
4o6zD01 - 13.6
132
25
3D
3bwoF01 - 67.1
95
25 - - 20.6
98
24 - - 37.4
99
24 - - 53.6
97
24 - - 62.2
100
23 - - 2.0
101
22 - - 88.9
102
21 - - 81.4
104
21 - - 74.6
108
20
3D
3k7yA01 - 16.9
106
20 - - 74.7
105
20 - - 32.2
124
19
3D
4raeB01 - 21.7
107
19 - - 11.9
109
19 - - 0.0
121
19
3D
3e77C02 - 67.9
119
18
3D
3k40B03 - 17.6
113
18
3D
2zy2A01 - 27.8
110
18 - - 18.9
112
18 - - 79.0
126
18
3D
4wb0B01 - 86.5
111
18 - - 5.4
114
17 - - 90.9
115
17 - - 9.4
165
17
3D
2jjhA01 - 12.6
118
16 - - 16.9
116
decarboxylating
16 - - 44.1
120
16 - - 81.9
117
16 - - 72.0
122
15 - - 18.9
125
15 - - 8.1
123
15 - - 5.2
127
14 - - 22.0
129
14 - - 8.7
128
14 - - 5.4
130
14 - - 69.5
131
14 - - 54.0
139
13 - - 35.9
135
13 - - 65.8
152
13
3D
5viuB01 - 63.1
151
13
3D
3tcmB01 - 75.9
138
13 - - 0.0
137
13 - - 18.4
140
13 - - 83.7
133
13 - - 1.9
134
13 - - 24.9
144
12 - - 87.7
142
12 - - 43.2
143
12 - - 36.0
147
12
3D
5c6uA01 - 17.3
145
11 - - 72.6
150
11 - - 1.5
291
11
3D
5f8vH02 - 14.0
148
11 - - 79.5
149
11 - - 24.4
146
11 - - 0.0
350
10
3D
2ogeD02 - 0.0
153
decarboxylating
10 - - 49.6
160
10 - - 88.2
161
10 - - 92.6
155
10 - - 0.0
267
10
3D
2fnuB02 - 8.3
154
10 - - 0.0
159
decarboxylating
10 - - 13.7
266
10
3D
4k2mB02 - 0.9
158
10 - - 23.6
157
10 - - 29.6
156
10 - - 0.0
168
9 - - 4.1
167
9 - - 43.7
163
9 - - 0.0
162
9 - - 9.9
169
9 - - 0.0
289
AgxT
9
3D
3zrrB02 - 0.0
164
9 - - 22.5
178
8 - - 8.1
180
8 - - 17.8
177
8 - - 15.8
171
8 - - 0.0
366
8
3D
3nubB02 - 0.0
187
8 - - 86.9
176
8 - - 7.1
170
8 - - 0.0
182
8 - - 13.1
250
8
3D
4w5kB01 - 58.1
175
8 - - 8.9
184
8 - - 70.6
181
8 - - 78.4
174
8 - - 22.1
188
8 - - 73.3
183
8 - - 7.9
186
8 - - 21.8
172
8 - - 37.9
179
8 - - 0.0
173
8 - - 0.0
185
8 - - 14.8
194
7 - - 0.0
193
7 - - 11.5
189
7 - - 4.5
200
decarboxylating
7 - - 9.0
197
7 - - 0.9
192
7 - - 18.0
199
7 - - 88.9
198
7 - - 0.0
202
7 - - 11.3
195
7 - - 15.3
201
decarboxylating
7 - - 13.8
190
7 - - 78.0
203
7 - - 83.2
196
7 - - 12.2
206
6 - - 18.2
220
6 - - 62.0
211
6 - - 8.4
218
6 - - 52.2
205
6 - - 28.7
213
6 - - 0.0
212
6 - - 15.1
207
6 - - 17.4
215
6 - - 21.3
208
6 - - 15.6
214
6 - - 3.0
217
6 - - 0.0
204
6 - - 86.1
209
6 - - 0.0
216
6 - - 0.0
210
6 - - 0.0
219
6 - - 55.4
226
5 - - 0.0
236
5 - - 10.7
234
5 - - 80.7
244
5 - - 0.0
246
5 - - 36.9
221
5 - - 0.7
237
5 - - 1.0
235
5 - - 10.5
224
5 - - 0.0
227
5 - - 13.1
232
5 - - 0.0
225
5 - - 6.1
245
5 - - 68.3
233
5 - - 45.8
241
5 - - 0.0
240
5 - - 1.4
230
5 - - 0.0
229
5 - - 11.6
222
5 - - 16.8
239
5 - - 8.7
243
5 - - 0.0
231
5 - - 12.0
228
5 - - 1.8
223
decarboxylating
5 - - 0.0
238
5 - - 14.9
242
5 - - 0.0
260
4 - - 10.3
254
4 - - 0.0
265
4 - - 0.0
272
4 - - 0.0
275
4 - - 23.9
262
4 - - 87.0
251
4 - - 0.0
256
4 - - 0.0
264
4 - - 16.5
255
4 - - 4.1
263
4 - - 6.4
274
4 - - 63.5
257
4 - - 8.8
276
4 - - 78.2
259
4 - - 11.6
273
4 - - 24.6
249
4 - - 7.4
270
4 - - 0.0
269
4 - - 12.4
261
4 - - 73.6
247
4 - - 79.7
268
4 - - 3.7
253
4 - - 9.6
277
4 - - 57.7
258
4 - - 3.8
252
4 - - 0.0
271
4 - - 0.0
248
4 - - 16.6
285
3 - - 0.0
288
3 - - 0.0
295
3 - - 10.3
300
3 - - 2.2
286
3 - - 12.1
301
3 - - 24.2
296
3 - - 0.0
287
3 - - 0.9
294
3 - - 0.0
279
3 - - 16.6
293
decarboxylating
3 - - 6.3
303
3 - - 76.1
278
3 - - 19.3
292
3 - - 8.6
280
3 - - 44.3
299
3 - - 2.9
302
3 - - 39.1
305
3 - - 52.4
281
3 - - 3.2
298
3 - - 12.4
284
3 - - 0.0
345
3
3D
3ihjA01 - 31.4
282
3 - - 0.0
297
3 - - 2.6
290
3 - - 6.8
304
3 - - 60.4
306
3 - - 80.2
283
3 - - 0.9
358
2 - - 0.0
331
2 - - 4.6
325
S
2 - - 9.5
378
2 - - 10.5
337
2 - - 2.4
382
2 - - 12.7
340
2 - - 0.0
311
2 - - 5.6
389
2 - - 7.4
348
2 - - 6.6
364
2 - - 0.0
388
2 - - 41.9
367
2 - - 0.0
391
2 - - 40.4
324
2 - - 2.3
351
2 - - 1.0
379
2 - - 0.0
342
2 - - 35.8
341
Eurofung
2 - - 0.0
312
2 - - 4.2
370
2 - - 0.0
309
2 - - 1.0
380
decarboxylating
2 - - 5.1
381
2 - - 35.9
308
2 - - 0.0
392
2 - - 46.5
373
2 - - 22.0
386
2 - - 0.0
329
2 - - 0.0
349
2 - - 0.0
346
2 - - 44.8
333
2 - - 0.9
323
2 - - 1.5
352
2 - - 0.0
369
2 - - 0.0
372
Thiol
2 - - 7.3
359
2 - - 1.0
330
2 - - 0.0
360
2 - - 1.0
322
2 - - 0.0
353
2 - - 2.0
375
2 - - 0.0
310
2 - - 0.0
387
decarboxylating
2 - - 0.0
354
2 - - 0.0
332
2 - - 0.0
368
2 - - 0.0
316
2 - - 9.2
347
2 - - 9.0
374
2 - - 0.0
327
2 - - 0.0
320
2 - - 0.0
361
2 - - 0.0
385
2 - - 0.0
314
2 - - 40.6
307
2 - - 2.7
355
2 - - 10.3
326
2 - - 0.0
335
2 - - 1.0
334
2 - - 0.0
377
2 - - 1.2
315
2 - - 10.0
338
2 - - 0.0
328
2 - - 7.1
363
2 - - 0.0
362
2 - - 0.0
317
2 - - 0.0
384
2 - - 0.0
376
2 - - 0.0
313
2 - - 34.9
343
2 - - 48.6
321
2 - - 0.0
371
2 - - 0.0
339
2 - - 0.0
319
2 - - 0.0
344
2 - - 45.7
357
2 - - 0.0
336
2 - - 8.8
383
2 - - 0.0
365
2 - - 10.8
318
2 - - 0.0
390
2 - - 19.3
356
2 - - 0.0
443
1 - - 0.0
512
1 - - 0.0
437
1 - - 0.0
463
1 - - 0.0
517
1 - - 0.0
458
1 - - 0.0
451
1 - - 0.0
454
1 - - 0.0
431
1 - - 0.0
527
1 - - 0.0
495
1 - - 0.0
418
1 - - 0.0
486
1 - - 0.0
509
1 - - 0.0
485
1 - - 0.0
523
1 - - 0.0
460
1 - - 0.0
453
1 - - 0.0
410
1 - - 0.0
488
1 - - 0.0
430
1 - - 0.0
447
1 - - 0.0
415
1 - - 0.0
452
1 - - 0.0
480
1 - - 0.0
438
1 - - 0.0
535
1 - - 0.0
444
1 - - 0.0
508
1 - - 0.0
417
1 - - 0.0
405
1 - - 0.0
507
1 - - 0.0
506
1 - - 0.0
416
1 - - 0.0
496
1 - - 0.0
399
1 - - 0.0
436
1 - - 0.0
456
1 - - 0.0
493
1 - - 0.0
445
1 - - 0.0
525
1 - - 0.0
400
1 - - 0.0
534
1 - - 0.0
468
1 - - 0.0
441
1 - - 0.0
475
1 - - 0.0
413
1 - - 0.0
515
1 - - 0.0
432
1 - - 0.0
519
1 - - 0.0
427
1 - - 0.0
446
1 - - 0.0
426
1 - - 0.0
498
1 - - 0.0
483
1 - - 0.0
428
1 - - 0.0
526
1 - - 0.0
500
1 - - 0.0
533
1 - - 0.0
414
1 - - 0.0
462
1 - - 0.0
477
1 - - 0.0
394
1 - - 0.0
514
1 - - 0.0
513
1 - - 0.0
476
1 - - 0.0
510
1 - - 0.0
449
1 - - 0.0
469
1 - - 0.0
501
1 - - 0.0
490
1 - - 0.0
461
1 - - 0.0
425
1 - - 0.0
520
1 - - 0.0
532
1 - - 0.0
424
1 - - 0.0
395
1 - - 0.0
492
1 - - 0.0
511
1 - - 0.0
434
1 - - 0.0
442
1 - - 0.0
429
1 - - 0.0
409
1 - - 0.0
489
1 - - 0.0
471
DegT/DnrJ/Eryc1 family
1 - - 0.0
465
1 - - 0.0
412
1 - - 0.0
502
1 - - 0.0
479
1 - - 0.0
524
1 - - 0.0
521
1 - - 0.0
433
1 - - 0.0
440
1 - - 0.0
423
1 - - 0.0
467
1 - - 0.0
481
1 - - 0.0
474
1 - - 0.0
422
1 - - 0.0
503
1 - - 0.0
402
1 - - 0.0
484
1 - - 0.0
464
1 - - 0.0
518
1 - - 0.0
497
1 - - 0.0
472
1 - - 0.0
439
1 - - 0.0
411
1 - - 0.0
478
1 - - 0.0
398
1 - - 0.0
407
1 - - 0.0
522
1 - - 0.0
529
1 - - 0.0
504
1 - - 0.0
397
1 - - 0.0
459
1 - - 0.0
435
1 - - 0.0
401
1 - - 0.0
531
1 - - 0.0
404
1 - - 0.0
516
1 - - 0.0
420
1 - - 0.0
494
1 - - 0.0
487
1 - - 0.0
448
1 - - 0.0
455
1 - - 0.0
457
1 - - 0.0
505
1 - - 0.0
419
1 - - 0.0
406
1 - - 0.0
396
1 - - 0.0
482
1 - - 0.0
499
1 - - 0.0
530
1 - - 0.0
470
1 - - 0.0
403
1 - - 0.0
466
1 - - 0.0
421
1 - - 0.0
450
1 - - 0.0
491
1 - - 0.0
473
1 - - 0.0
408
1 - - 0.0
528
1 - - 0.0