The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 57: Acid sphingomyelinase-like phosphodiesterase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphoric diester hydrolase activity GO:0008081
Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.
|
3 | P58242 (/IMP) P58242 (/IMP) Q92485 (/IMP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | P58242 (/IPI) P58242 (/IPI) |
|
Phosphoric diester hydrolase activity GO:0008081
Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.
|
2 | P58242 (/IDA) P58242 (/IDA) |
|
Phosphoric diester hydrolase activity GO:0008081
Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.
|
2 | P58242 (/ISO) P58242 (/ISO) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
2 | P58242 (/IDA) P58242 (/IDA) |
|
Phosphoric diester hydrolase activity GO:0008081
Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.
|
1 | Q92485 (/ISS) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | Q92485 (/ISS) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of toll-like receptor signaling pathway GO:0034122
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway.
|
2 | P58242 (/IMP) P58242 (/IMP) |
|
Negative regulation of innate immune response GO:0045824
Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response.
|
2 | P58242 (/TAS) P58242 (/TAS) |
|
Membrane lipid catabolic process GO:0046466
The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane.
|
2 | P58242 (/IMP) P58242 (/IMP) |
|
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
|
2 | P58242 (/IMP) P58242 (/IMP) |
|
Negative regulation of toll-like receptor signaling pathway GO:0034122
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway.
|
1 | Q92485 (/ISS) |
|
Membrane lipid catabolic process GO:0046466
The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane.
|
1 | Q92485 (/ISS) |
|
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
|
1 | Q92485 (/ISS) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | P58242 (/IDA) P58242 (/IDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q92485 (/HDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q92485 (/ISS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q92485 (/HDA) |