The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Metallo-dependent phosphatases

This entry represents a domain found in metallo-dependent phosphatases. Proteins containing this domain include:

Purple acid phosphatases PMID:10438611, DNA double-strand break repair nucleases PMID:11371344, 5'-nucleotidases (syn. UDP-sugar hydrolase), protein serine/threonine phosphatase, phosphoesterase-related proteins, TT1561-like proteins, YfcE-like proteins, hypothetical protein aq_1666, DR1281-like proteins, TTHA0625-like proteins, GpdQ-like proteins and ADPRibase-Mn-like proteins.

Metallophosphatases (MPPs), also known as metallophosphoesterases, phosphodiesterases (PDEs), binuclear metallophosphoesterases, and dimetal-containing phosphoesterases (DMPs), represent a diverse superfamily of enzymes with a conserved domain containing an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues PMID:18757371,PMID:25837850.

PMID:10438611 PMID:11371344 PMID:18757371 PMID:25837850

GO Diversity

Unique GO annotations
770 Unique GO terms

EC Diversity

Unique EC annotations
24 Unique EC terms

Species Diversity

Unique species annotations
23087 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 457
Domain clusters (>95% seq id): 67
Domain clusters (>35% seq id): 43
Unique PDBs: 229
Structural Clusters (5A): 12
Structural Clusters (9A): 5
FunFam Clusters: 497
Unique EC: 24
Unique GO: 770
Unique Species: 23087