The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1: Serine/threonine-protein phosphatase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
32 P13681 (/IPI) P23880 (/IPI) P32598 (/IPI) P32598 (/IPI) P32598 (/IPI) P32598 (/IPI) P32598 (/IPI) P32598 (/IPI) P48484 (/IPI) P48484 (/IPI)
(22 more)
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
23 O82734 (/IDA) P13681 (/IDA) P30366 (/IDA) P30366 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA)
(13 more)
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
12 P48482 (/ISS) P48482 (/ISS) P48482 (/ISS) P48483 (/ISS) P48483 (/ISS) P48484 (/ISS) P48484 (/ISS) P48485 (/ISS) P48485 (/ISS) Q5K375 (/ISS)
(2 more)
Hydrolase activity GO:0016787
Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
4 Q384L0 (/ISM) Q384L0 (/ISM) Q384L0 (/ISM) Q384L0 (/ISM)
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
3 Q59N42 (/NAS) Q59N42 (/NAS) Q59N42 (/NAS)
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
1 P13681 (/EXP)
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
1 P13681 (/IMP)
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
1 P23880 (/ISO)
RNA polymerase II CTD heptapeptide repeat phosphatase activity GO:0008420
Catalysis of the reaction: phospho-(DNA-directed RNA polymerase II) + H2O = (DNA-directed RNA polymerase II) + phosphate.
1 P13681 (/IDA)

There are 49 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
25 Q5K375 (/ISS) Q5LJN2 (/ISS) Q8ILV1 (/ISS) Q8ILV1 (/ISS) Q8ILV1 (/ISS) Q8ILV1 (/ISS) Q8ILV1 (/ISS) Q8ILV1 (/ISS) Q8ILV1 (/ISS) Q8ILV1 (/ISS)
(15 more)
DNA damage checkpoint GO:0000077
A cell cycle checkpoint that regulates progression through the cell cycle in response to DNA damage. A DNA damage checkpoint may blocks cell cycle progression (in G1, G2 or metaphase) or slow the rate at which S phase proceeds.
9 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) Q59N42 (/IMP) Q59N42 (/IMP) Q59N42 (/IMP)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
7 P48482 (/TAS) P48482 (/TAS) P48482 (/TAS) P48483 (/TAS) P48483 (/TAS) P48484 (/TAS) P48484 (/TAS)
Chromosome segregation GO:0007059
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
7 P20654 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
DNA replication checkpoint GO:0000076
A cell cycle checkpoint that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.
6 P32598 (/IGI) P32598 (/IGI) P32598 (/IGI) P32598 (/IGI) P32598 (/IGI) P32598 (/IGI)
DNA replication checkpoint GO:0000076
A cell cycle checkpoint that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Telomere maintenance GO:0000723
Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
6 P32598 (/IGI) P32598 (/IGI) P32598 (/IGI) P32598 (/IGI) P32598 (/IGI) P32598 (/IGI)
Glycogen metabolic process GO:0005977
The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Regulation of carbohydrate metabolic process GO:0006109
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.
6 P32598 (/IGI) P32598 (/IGI) P32598 (/IGI) P32598 (/IGI) P32598 (/IGI) P32598 (/IGI)
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
6 P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Cellular ion homeostasis GO:0006873
Any process involved in the maintenance of an internal steady state of ions at the level of a cell.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Response to unfolded protein GO:0006986
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Mitotic spindle assembly checkpoint GO:0007094
A cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Cell budding GO:0007114
A form of asexual reproduction, occurring in certain bacteria and fungi (e.g. yeasts) and some primitive animals in which an individual arises from a daughter cell formed by pinching off a part of the parent cell. The budlike outgrowths so formed may sometimes remain attached to the parent cell.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Regulation of mitotic cell cycle GO:0007346
Any process that modulates the rate or extent of progress through the mitotic cell cycle.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
6 P32598 (/IGI) P32598 (/IGI) P32598 (/IGI) P32598 (/IGI) P32598 (/IGI) P32598 (/IGI)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Histone dephosphorylation GO:0016576
The modification of histones by removal of phosphate groups.
6 P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA)
Histone dephosphorylation GO:0016576
The modification of histones by removal of phosphate groups.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Ascospore formation GO:0030437
The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota).
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Termination of RNA polymerase II transcription, poly(A)-coupled GO:0030846
The process in which transcription of polyadenylated RNA polymerase II transcripts is terminated; cleavage and polyadenylylation of the mRNA 3' end is coupled to transcription termination.
6 P32598 (/IPI) P32598 (/IPI) P32598 (/IPI) P32598 (/IPI) P32598 (/IPI) P32598 (/IPI)
Termination of RNA polymerase II transcription, exosome-dependent GO:0030847
The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end.
6 P32598 (/IPI) P32598 (/IPI) P32598 (/IPI) P32598 (/IPI) P32598 (/IPI) P32598 (/IPI)
Replication fork processing GO:0031297
The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Protein localization to kinetochore GO:0034501
Any process in which a protein is transported to, or maintained at, the kinetochore.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Positive regulation of protein dephosphorylation GO:0035307
Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Meiotic cell cycle GO:0051321
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
6 P32598 (/IPI) P32598 (/IPI) P32598 (/IPI) P32598 (/IPI) P32598 (/IPI) P32598 (/IPI)
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Transfer RNA gene-mediated silencing GO:0061587
The chromatin silencing that results in the inhibition of RNA polymerase II-transcribed genes located in the vicinity of tRNA genes.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Dephosphorylation of RNA polymerase II C-terminal domain GO:0070940
The process of removing a phosphate group from an amino acid residue in the C-terminal domain of RNA polymerase II. Some dephosphorylation occurs during transcription while some may occur after the enzyme is released from the template in order to prepare it for the beginning of the transcription cycle again. RNA polymerase II with little or no phosphorylation is referred to as the hypophosphorylated or II(A) form.
6 P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA)
Regulation of protein localization to cell division site involved in cytokinesis GO:1901901
Any regulation of protein localization to cell division site that is involved in cytokinesis.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Positive regulation of mitotic actomyosin contractile ring assembly GO:1903501
Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring assembly.
6 P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP) P32598 (/IMP)
Positive regulation of clathrin-dependent endocytosis GO:2000370
Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis.
6 P32598 (/IGI) P32598 (/IGI) P32598 (/IGI) P32598 (/IGI) P32598 (/IGI) P32598 (/IGI)
Pollen tube growth GO:0009860
Growth of pollen via tip extension of the intine wall.
3 O82734 (/IGI) Q9M9W3 (/IGI) Q9M9W3 (/IGI)
Root hair cell tip growth GO:0048768
Localized growth of a plant root hair tip by extension of the cell wall.
3 O82734 (/IGI) Q9M9W3 (/IGI) Q9M9W3 (/IGI)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
2 P48484 (/IPI) P48484 (/IPI)
Red light signaling pathway GO:0010161
The series of molecular signals initiated upon sensing of red light by a photoreceptor molecule. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
2 P48484 (/IGI) P48484 (/IGI)
Red light signaling pathway GO:0010161
The series of molecular signals initiated upon sensing of red light by a photoreceptor molecule. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
2 P48484 (/IMP) P48484 (/IMP)
Positive regulation of establishment of cell polarity regulating cell shape GO:2000784
Any process that activates or increases the frequency, rate or extent of establishment of cell polarity regulating cell shape.
2 P13681 (/EXP) P23880 (/EXP)
Mitotic spindle elongation GO:0000022
The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.
1 P20654 (/IMP)
Signaling GO:0023052
The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
1 P13681 (/IC)
Establishment of cell polarity GO:0030010
The specification and formation of anisotropic intracellular organization or cell growth patterns.
1 P20654 (/IMP)
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
1 P13681 (/IMP)
Anisotropic cell growth GO:0051211
The process in which a cell irreversibly increases in size in one or more axes, where the growth rate varies according to the direction of growth. Growth may be limited to a particular axis, axes, or to particular locations on the surface of the cell.
1 P20654 (/IMP)
Attachment of mitotic spindle microtubules to kinetochore GO:0051315
The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression.
1 P13681 (/IGI)
Deactivation of mitotic spindle assembly checkpoint GO:1902426
A positive regulation of the mitotic metaphase/anaphase transition that results from deactivation of the mitotic spindle assembly checkpoint.
1 P13681 (/IMP)
Positive regulation of protein localization to cell tip GO:1903068
Any process that activates or increases the frequency, rate or extent of protein localization to cell tip.
1 P13681 (/EXP)
Positive regulation of termination of RNA polymerase II transcription GO:1904595
Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription.
1 P13681 (/IMP)

There are 34 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Maurer's cleft GO:0020036
A disk-like structure that appears at the periphery of a red blood cell infected by an apicomplexan parasite, characterized by a translucent lumen and an electron-dense coat of variable thickness; often appears to be tethered to the host cell membrane by fibrous connections with the erythrocyte cytoskeleton.
22 Q8ILV1 (/IDA) Q8ILV1 (/IDA) Q8ILV1 (/IDA) Q8ILV1 (/IDA) Q8ILV1 (/IDA) Q8ILV1 (/IDA) Q8ILV1 (/IDA) Q8ILV1 (/IDA) Q8ILV1 (/IDA) Q8ILV1 (/IDA)
(12 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
17 O82734 (/IDA) P13681 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P48483 (/IDA) P48483 (/IDA)
(7 more)
Protein phosphatase type 1 complex GO:0000164
A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity.
11 P30366 (/ISS) P30366 (/ISS) P48482 (/ISS) P48482 (/ISS) P48482 (/ISS) P48483 (/ISS) P48483 (/ISS) P48484 (/ISS) P48484 (/ISS) P48485 (/ISS)
(1 more)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
10 P20654 (/IDA) P23880 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P48483 (/IDA) P48483 (/IDA)
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
9 P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) Q59N42 (/IDA) Q59N42 (/IDA) Q59N42 (/IDA)
Protein phosphatase type 1 complex GO:0000164
A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity.
8 P13681 (/IPI) P23880 (/IPI) P32598 (/IPI) P32598 (/IPI) P32598 (/IPI) P32598 (/IPI) P32598 (/IPI) P32598 (/IPI)
Spindle pole body GO:0005816
The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.
7 P20654 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA)
MRNA cleavage and polyadenylation specificity factor complex GO:0005847
A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
7 P13681 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA)
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
7 P13681 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA)
Protein phosphatase type 1 complex GO:0000164
A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity.
6 P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA)
Condensed nuclear chromosome kinetochore GO:0000778
A multisubunit complex that is located at the centromeric region of a condensed nuclear chromosome and provides an attachment point for the spindle microtubules.
6 P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA)
Mating projection base GO:0001400
The region where the mating projection meets the bulk of the cell, in unicellular fungi exposed to mating pheromone.
6 P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA) P32598 (/IDA)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
4 Q384L0 (/IDA) Q384L0 (/IDA) Q384L0 (/IDA) Q384L0 (/IDA)
Ciliary basal body GO:0036064
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
4 Q384L0 (/IDA) Q384L0 (/IDA) Q384L0 (/IDA) Q384L0 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q5K375 (/ISS) Q5LJN2 (/ISS) Q95V51 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q5K375 (/ISS) Q5LJN2 (/ISS) Q95V51 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 O82734 (/IDA) Q9M9W3 (/IDA) Q9M9W3 (/IDA)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
2 P13681 (/IDA) P23880 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P13681 (/HDA) P23880 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P48483 (/IDA) P48483 (/IDA)
PTW/PP1 phosphatase complex GO:0072357
A protein serine/threonine phosphatase complex that contains a catalytic subunit (PPP1CA, PPP1CB or PPP1CC) and the regulatory subunits PPP1R10 (PNUTS), TOX4 and WDR82, and plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
2 P13681 (/IPI) P23880 (/IPI)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 P23880 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P13681 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P13681 (/HDA)
MRNA cleavage and polyadenylation specificity factor complex GO:0005847
A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
1 P13681 (/IPI)
Cell septum GO:0030428
A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.
1 P20654 (/IDA)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
1 Q4Q8K1 (/ISO)
Non-growing cell tip GO:0035839
A cell tip at which no growth takes place. For example, in fission yeast the cell end newly formed by cell division does not grow immediately upon its formation, and lacks actin cytoskeletal structures.
1 P13681 (/IDA)
Ciliary basal body GO:0036064
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
1 Q4Q8K1 (/ISO)
Cell cortex of cell tip GO:0051285
The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell.
1 P13681 (/IDA)
Cell tip GO:0051286
The region at the end of the longest axis of a cylindrical or elongated cell.
1 P13681 (/IDA)
CENP-A containing chromatin GO:0061638
The specialized chromatin located the centromeric core region or the entire centromeric region in organisms with point centromeres, which is enriched for CENP-A-containing nucleosomes. This chromatin forms a 3-dimensional structure which provides a platform for kinetochore assembly and microtubule attachment.
1 P13681 (/IDA)
Cell cortex of growing cell tip GO:1902716
Any cell cortex that is part of a growing cell tip.
1 P13681 (/IDA)
DPS complex GO:1990567
A protein serine/threonine phosphatase complex that in S. pombe consists of the proteins Dis2, Ppn1, and Swd22.
1 P13681 (/IDA)