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CATH Superfamily 3.40.710.10

DD-peptidase/beta-lactamase superfamily

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
DD-peptidase/beta-lactamase superfamily
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: D-alanyl-D-alanine serine-type carboxypeptidase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Penicillin binding GO:0008658
Interacting selectively and non-covalently with penicillin, any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
 168 P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA)
(158 more)
Carboxypeptidase activity GO:0004180
Catalysis of the hydrolysis of the terminal or penultimate peptide bond at the C-terminal end of a peptide or polypeptide.
 157 P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA)
(147 more)
Carboxypeptidase activity GO:0004180
Catalysis of the hydrolysis of the terminal or penultimate peptide bond at the C-terminal end of a peptide or polypeptide.
 149 P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP)
(139 more)
Serine-type D-Ala-D-Ala carboxypeptidase activity GO:0009002
Catalysis of the reaction: (Ac)2-L-Lys-D-alanyl-D-alanine + H2O = (Ac)2-L-Lys-D-alanine + D-alanine.
 138 P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA)
(128 more)
Serine-type D-Ala-D-Ala carboxypeptidase activity GO:0009002
Catalysis of the reaction: (Ac)2-L-Lys-D-alanyl-D-alanine + H2O = (Ac)2-L-Lys-D-alanine + D-alanine.
 138 P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP)
(128 more)
Serine-type D-Ala-D-Ala carboxypeptidase activity GO:0009002
Catalysis of the reaction: (Ac)2-L-Lys-D-alanyl-D-alanine + H2O = (Ac)2-L-Lys-D-alanine + D-alanine.
 8 Q9KMQ0 (/ISS) Q9KMQ0 (/ISS) Q9KMQ0 (/ISS) Q9KMQ0 (/ISS) Q9KMQ0 (/ISS) Q9KMQ0 (/ISS) Q9KMQ0 (/ISS) Q9KTF5 (/ISS)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
 168 P08506 (/IGI) P08506 (/IGI) P08506 (/IGI) P08506 (/IGI) P08506 (/IGI) P08506 (/IGI) P08506 (/IGI) P08506 (/IGI) P08506 (/IGI) P08506 (/IGI)
(158 more)
Peptidoglycan metabolic process GO:0000270
The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network.
 138 P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA)
(128 more)
Peptidoglycan metabolic process GO:0000270
The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network.
 138 P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP)
(128 more)
Cell wall macromolecule metabolic process GO:0044036
The chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
 138 P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA) P0AEB2 (/IDA)
(128 more)
Cell wall macromolecule metabolic process GO:0044036
The chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
 138 P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP) P0AEB2 (/IMP)
(128 more)
Peptidoglycan biosynthetic process GO:0009252
The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
 19 P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA)
(9 more)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
 19 P08506 (/IMP) P08506 (/IMP) P08506 (/IMP) P08506 (/IMP) P08506 (/IMP) P08506 (/IMP) P08506 (/IMP) P08506 (/IMP) P08506 (/IMP) P08506 (/IMP)
(9 more)
Peptidoglycan biosynthetic process GO:0009252
The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
 11 P33013 (/IMP) P33013 (/IMP) P33013 (/IMP) P33013 (/IMP) P33013 (/IMP) P33013 (/IMP) P33013 (/IMP) P33013 (/IMP) P33013 (/IMP) P33013 (/IMP)
(1 more)
Peptidoglycan biosynthetic process GO:0009252
The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
 9 Q8EHQ3 (/ISS) Q9KMQ0 (/ISS) Q9KMQ0 (/ISS) Q9KMQ0 (/ISS) Q9KMQ0 (/ISS) Q9KMQ0 (/ISS) Q9KMQ0 (/ISS) Q9KMQ0 (/ISS) Q9KTF5 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 157 P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA) P08506 (/IDA)
(147 more)