The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 52: Aspartate aminotransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
L-aspartate:2-oxoglutarate aminotransferase activity GO:0004069
Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
10 P28734 (/ISS) P37833 (/ISS) P37833 (/ISS) P37833 (/ISS) P46644 (/ISS) P46644 (/ISS) P46645 (/ISS) P46645 (/ISS) P46645 (/ISS) P46646 (/ISS)
L-aspartate:2-oxoglutarate aminotransferase activity GO:0004069
Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
3 P46645 (/IDA) P46645 (/IDA) P46645 (/IDA)
L-aspartate:2-oxoglutarate aminotransferase activity GO:0004069
Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
3 P37833 (/IEP) P37833 (/IEP) P37833 (/IEP)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
3 P46645 (/IDA) P46645 (/IDA) P46645 (/IDA)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
2-oxoglutarate metabolic process GO:0006103
The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism.
10 P28734 (/ISS) P37833 (/ISS) P37833 (/ISS) P37833 (/ISS) P46644 (/ISS) P46644 (/ISS) P46645 (/ISS) P46645 (/ISS) P46645 (/ISS) P46646 (/ISS)
Aspartate metabolic process GO:0006531
The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.
10 P28734 (/ISS) P37833 (/ISS) P37833 (/ISS) P37833 (/ISS) P46644 (/ISS) P46644 (/ISS) P46645 (/ISS) P46645 (/ISS) P46645 (/ISS) P46646 (/ISS)
Glutamate metabolic process GO:0006536
The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.
10 P28734 (/ISS) P37833 (/ISS) P37833 (/ISS) P37833 (/ISS) P46644 (/ISS) P46644 (/ISS) P46645 (/ISS) P46645 (/ISS) P46645 (/ISS) P46646 (/ISS)
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
3 P37833 (/ISS) P37833 (/ISS) P37833 (/ISS)
Alanine metabolic process GO:0006522
The chemical reactions and pathways involving alanine, 2-aminopropanoic acid.
3 P37833 (/ISS) P37833 (/ISS) P37833 (/ISS)
Nitrogen compound metabolic process GO:0006807
The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
3 P46645 (/IMP) P46645 (/IMP) P46645 (/IMP)
Nitrogen compound metabolic process GO:0006807
The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
3 P37833 (/ISS) P37833 (/ISS) P37833 (/ISS)
Leaf senescence GO:0010150
The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.
2 P46644 (/IEP) P46644 (/IEP)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
3 P46645 (/IDA) P46645 (/IDA) P46645 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P37833 (/ISS) P37833 (/ISS) P37833 (/ISS)
Vacuolar membrane GO:0005774
The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
3 P46645 (/IDA) P46645 (/IDA) P46645 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 P46645 (/IDA) P46645 (/IDA) P46645 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 P46645 (/IDA) P46645 (/IDA) P46645 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
3 P46645 (/IDA) P46645 (/IDA) P46645 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
2 P46644 (/IDA) P46644 (/IDA)
Plastid GO:0009536
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
2 P46644 (/IDA) P46644 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 P46644 (/IDA) P46644 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 F4I0D4 (/ISS)