The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 24: Kynurenine--oxoglutarate transaminase 3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 19 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Kynurenine-oxoglutarate transaminase activity GO:0016212
Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate.
10 P47039 (/ISS) P47039 (/ISS) Q08415 (/ISS) Q0P5G4 (/ISS) Q58FK9 (/ISS) Q6YP21 (/ISS) Q6YP21 (/ISS) Q7T3E5 (/ISS) Q8BTY1 (/ISS) Q8BTY1 (/ISS)
Kynurenine-oxoglutarate transaminase activity GO:0016212
Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate.
5 P47039 (/IDA) P47039 (/IDA) Q16773 (/IDA) Q16773 (/IDA) Q71RI9 (/IDA)
Kynurenine-glyoxylate transaminase activity GO:0047315
Catalysis of the reaction: L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine.
5 Q0P5G4 (/ISS) Q58FK9 (/ISS) Q6YP21 (/ISS) Q6YP21 (/ISS) Q7T3E5 (/ISS)
Kynurenine-oxoglutarate transaminase activity GO:0016212
Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate.
3 O14209 (/ISO) Q8BTY1 (/ISO) Q8BTY1 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
3 Q16773 (/IPI) Q16773 (/IPI) Q71RI9 (/IPI)
Cysteine-S-conjugate beta-lyase activity GO:0047804
Catalysis of the reaction: RS-CH2-CH(NH3+)COO- = RSH + NH3 + pyruvate.
3 Q08415 (/IDA) Q16773 (/IDA) Q16773 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
2 Q6YP21 (/HDA) Q6YP21 (/HDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q16773 (/IPI) Q16773 (/IPI)
Transaminase activity GO:0008483
Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid.
2 Q16773 (/TAS) Q16773 (/TAS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q8BTY1 (/ISO) Q8BTY1 (/ISO)
Glutamine-phenylpyruvate transaminase activity GO:0047316
Catalysis of the reaction: keto-phenylpyruvate + L-glutamine = 2-oxoglutaramate + L-phenylalanine.
2 Q8BTY1 (/ISO) Q8BTY1 (/ISO)
2-aminoadipate transaminase activity GO:0047536
Catalysis of the reaction: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate.
2 P47039 (/IDA) P47039 (/IDA)
Cysteine-S-conjugate beta-lyase activity GO:0047804
Catalysis of the reaction: RS-CH2-CH(NH3+)COO- = RSH + NH3 + pyruvate.
2 Q8BTY1 (/ISO) Q8BTY1 (/ISO)
Arylformamidase activity GO:0004061
Catalysis of the reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine.
1 A0A1D8PGR0 (/ISA)
Transaminase activity GO:0008483
Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid.
1 Q54KM6 (/ISS)
Kynurenine-glyoxylate transaminase activity GO:0047315
Catalysis of the reaction: L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine.
1 Q71RI9 (/IDA)
Glutamine-phenylpyruvate transaminase activity GO:0047316
Catalysis of the reaction: keto-phenylpyruvate + L-glutamine = 2-oxoglutaramate + L-phenylalanine.
1 Q08415 (/IDA)
2-aminoadipate transaminase activity GO:0047536
Catalysis of the reaction: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate.
1 O14209 (/ISO)
Cysteine-S-conjugate beta-lyase activity GO:0047804
Catalysis of the reaction: RS-CH2-CH(NH3+)COO- = RSH + NH3 + pyruvate.
1 Q8SXC2 (/ISS)

There are 18 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Kynurenine metabolic process GO:0070189
The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine.
8 Q08415 (/ISS) Q0P5G4 (/ISS) Q58FK9 (/ISS) Q6YP21 (/ISS) Q6YP21 (/ISS) Q7T3E5 (/ISS) Q8BTY1 (/ISS) Q8BTY1 (/ISS)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
5 Q0P5G4 (/ISS) Q58FK9 (/ISS) Q6YP21 (/ISS) Q6YP21 (/ISS) Q7T3E5 (/ISS)
Kynurenine metabolic process GO:0070189
The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine.
3 Q16773 (/IDA) Q16773 (/IDA) Q71RI9 (/IDA)
Pyruvate metabolic process GO:0006090
The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
2 Q8BTY1 (/ISO) Q8BTY1 (/ISO)
L-phenylalanine catabolic process GO:0006559
The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid.
2 Q16773 (/TAS) Q16773 (/TAS)
Tryptophan catabolic process GO:0006569
The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
2 Q16773 (/TAS) Q16773 (/TAS)
Cellular modified amino acid metabolic process GO:0006575
The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.
2 Q16773 (/TAS) Q16773 (/TAS)
Cellular amino acid biosynthetic process GO:0008652
The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
2 Q16773 (/TAS) Q16773 (/TAS)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
2 Q8BTY1 (/IEP) Q8BTY1 (/IEP)
Kynurenic acid biosynthetic process GO:0034276
The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.
2 P47039 (/IDA) P47039 (/IDA)
Kynurenine metabolic process GO:0070189
The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine.
2 Q8BTY1 (/ISO) Q8BTY1 (/ISO)
L-kynurenine metabolic process GO:0097052
The chemical reactions and pathways involving L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine).
2 Q8BTY1 (/ISO) Q8BTY1 (/ISO)
Pyruvate metabolic process GO:0006090
The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
1 Q08415 (/IDA)
2-oxoglutarate metabolic process GO:0006103
The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism.
1 Q71RI9 (/IDA)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
1 Q71RI9 (/IDA)
Kynurenic acid biosynthetic process GO:0034276
The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.
1 O14209 (/ISO)
'de novo' NAD biosynthetic process from tryptophan GO:0034354
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
1 A0A1D8PGR0 (/ISA)
L-kynurenine metabolic process GO:0097052
The chemical reactions and pathways involving L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine).
1 Q08415 (/IDA)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
7 A8K563 (/IDA) A8K563 (/IDA) B7Z4W5 (/IDA) Q08415 (/IDA) Q16773 (/IDA) Q16773 (/IDA) Q5T278 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
5 A8K563 (/IDA) A8K563 (/IDA) B7Z4W5 (/IDA) Q16773 (/IDA) Q16773 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 P47039 (/HDA) P47039 (/HDA) Q71RI9 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 P47039 (/IDA) P47039 (/IDA) Q08415 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 O14209 (/ISO) Q8BTY1 (/ISO) Q8BTY1 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q8BTY1 (/ISO) Q8BTY1 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P47039 (/HDA) P47039 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P47039 (/IDA) P47039 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q8BTY1 (/ISO) Q8BTY1 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q16773 (/TAS) Q16773 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O14209 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O14209 (/HDA)