The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 1: Histone acetyltransferase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 33 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
30 |
O95251 (/IPI)
O95251 (/IPI)
O95251 (/IPI)
O95251 (/IPI)
O95251 (/IPI)
O95251 (/IPI)
O95251 (/IPI)
O95251 (/IPI)
O95251 (/IPI)
O95251 (/IPI)
(20 more) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
25 |
O95251 (/ISA)
O95251 (/ISA)
O95251 (/ISA)
O95251 (/ISA)
O95251 (/ISA)
O95251 (/ISA)
O95251 (/ISA)
O95251 (/ISA)
O95251 (/ISA)
O95251 (/ISA)
(15 more) |
|
DNA replication origin binding GO:0003688
Interacting selectively and non-covalently with the DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
|
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
|
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
|
7 | A2CG09 (/IDA) B3DK07 (/IDA) P34218 (/IDA) Q6J514 (/IDA) Q8BRB7 (/IDA) Q8WYB5 (/IDA) Q92794 (/IDA) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
4 | M9NEW2 (/IDA) Q7YTZ9 (/IDA) Q9NHW0 (/IDA) Q9VM15 (/IDA) |
|
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
|
4 | A2CG09 (/IMP) B3DK07 (/IMP) P34218 (/IMP) Q6J514 (/IMP) |
|
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
|
4 | Q5TKR9 (/ISS) Q8BRB7 (/ISS) Q8BZ21 (/ISS) Q8WML3 (/ISS) |
|
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
|
4 | M9NEW2 (/TAS) Q7YTZ9 (/TAS) Q9NHW0 (/TAS) Q9VM15 (/TAS) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
4 | M9NEW2 (/IPI) Q7YTZ9 (/IPI) Q9NHW0 (/IPI) Q9VM15 (/IPI) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
4 | Q5TKR9 (/ISS) Q8BRB7 (/ISS) Q8BZ21 (/ISS) Q8WML3 (/ISS) |
|
H3 histone acetyltransferase activity GO:0010484
Catalysis of the reaction: acetyl-CoA + histone H3 = CoA + acetyl-histone H3.
|
4 | M9NEW2 (/IDA) Q7YTZ9 (/IDA) Q9NHW0 (/IDA) Q9VM15 (/IDA) |
|
H4 histone acetyltransferase activity GO:0010485
Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.
|
4 | M9NEW2 (/IDA) Q7YTZ9 (/IDA) Q9NHW0 (/IDA) Q9VM15 (/IDA) |
|
Acetyltransferase activity GO:0016407
Catalysis of the transfer of an acetyl group to an acceptor molecule.
|
4 | Q5TKR9 (/ISS) Q8BRB7 (/ISS) Q8BZ21 (/ISS) Q8WML3 (/ISS) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
2 | Q5TKR9 (/ISS) Q8BZ21 (/ISS) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
2 | Q8WYB5 (/IDA) Q92794 (/IDA) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
2 | Q5TKR9 (/ISS) Q8BZ21 (/ISS) |
|
Acetyltransferase activity GO:0016407
Catalysis of the transfer of an acetyl group to an acceptor molecule.
|
2 | Q8WYB5 (/IDA) Q92794 (/IDA) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | Q92794 (/IDA) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | Q8BZ21 (/ISO) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
1 | Q8BZ21 (/IGI) |
|
DNA replication origin binding GO:0003688
Interacting selectively and non-covalently with the DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally.
|
1 | Q5SVQ0 (/ISO) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
1 | Q92794 (/TAS) |
|
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
|
1 | Q8BZ21 (/ISO) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
1 | Q8BZ21 (/ISO) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | Q92794 (/IDA) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | Q8BZ21 (/ISO) |
|
Acetyltransferase activity GO:0016407
Catalysis of the transfer of an acetyl group to an acceptor molecule.
|
1 | Q8BZ21 (/ISO) |
|
Acetyltransferase activity GO:0016407
Catalysis of the transfer of an acetyl group to an acceptor molecule.
|
1 | Q92794 (/TAS) |
|
Histone acetyltransferase activity (H3-K14 specific) GO:0036408
Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 14) = CoA + histone H3 N6-acetyl-L-lysine (position 14).
|
1 | Q10325 (/TAS) |
|
Histone acetyltransferase activity (H3-K23 specific) GO:0043994
Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 23) = CoA + histone H3 N6-acetyl-L-lysine (position 23).
|
1 | Q9W1A9 (/IDA) |
|
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
1 | Q5SVQ0 (/ISO) |
|
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
|
1 | Q8BRB7 (/ISO) |
There are 109 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
|
32 |
M9NEW2 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(22 more) |
|
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
25 |
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
(15 more) |
|
Internal peptidyl-lysine acetylation GO:0018393
The addition of an acetyl group to a non-terminal lysine residue in a protein.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
|
Stress-activated protein kinase signaling cascade GO:0031098
A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
|
Histone H4-K5 acetylation GO:0043981
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
|
Histone H4-K8 acetylation GO:0043982
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
|
Histone H4-K12 acetylation GO:0043983
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
|
Response to sorbitol GO:0072708
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
|
Response to hydroxyurea GO:0072710
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
|
Response to actinomycin D GO:0072716
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
|
Response to dithiothreitol GO:0072720
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
|
Response to anisomycin GO:0072739
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
|
Positive regulation of histone H4 acetylation GO:0090240
Any process that increases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.
|
25 |
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
O95251 (/IMP)
(15 more) |
|
Positive regulation of protein localization to nucleus GO:1900182
Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
|
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
|
7 | A2CG09 (/ISS) B3DK07 (/ISS) Q5TKR9 (/ISS) Q6J514 (/ISS) Q8BRB7 (/ISS) Q8BZ21 (/ISS) Q8WML3 (/ISS) |
|
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
|
6 | M9NEW2 (/IMP) P34218 (/IMP) Q7YTZ9 (/IMP) Q9NHW0 (/IMP) Q9VM15 (/IMP) Q9W1A9 (/IMP) |
|
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
|
6 | Q5SVQ0 (/ISS) Q5TKR9 (/ISS) Q810T5 (/ISS) Q8BRB7 (/ISS) Q8BZ21 (/ISS) Q8WML3 (/ISS) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
6 | M9NEW2 (/IDA) Q7YTZ9 (/IDA) Q8WYB5 (/IDA) Q92794 (/IDA) Q9NHW0 (/IDA) Q9VM15 (/IDA) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | M9NEW2 (/IMP) Q7YTZ9 (/IMP) Q9NHW0 (/IMP) Q9VM15 (/IMP) |
|
Negative regulation of cell fate specification GO:0009996
Any process that restricts, stops or prevents a cell from adopting a specific cell fate.
|
4 | M9NEW2 (/IMP) Q7YTZ9 (/IMP) Q9NHW0 (/IMP) Q9VM15 (/IMP) |
|
Sensory organ precursor cell fate determination GO:0016360
The process in which a cell becomes capable of differentiating autonomously into a sensory organ precursor cell regardless of its environment; upon determination, the cell fate cannot be reversed.
|
4 | M9NEW2 (/IMP) Q7YTZ9 (/IMP) Q9NHW0 (/IMP) Q9VM15 (/IMP) |
|
Gene silencing GO:0016458
Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression.
|
4 | M9NEW2 (/IGI) Q7YTZ9 (/IGI) Q9NHW0 (/IGI) Q9VM15 (/IGI) |
|
Gene silencing GO:0016458
Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression.
|
4 | M9NEW2 (/TAS) Q7YTZ9 (/TAS) Q9NHW0 (/TAS) Q9VM15 (/TAS) |
|
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
|
4 | P34218 (/IDA) Q8BRB7 (/IDA) Q8WYB5 (/IDA) Q92794 (/IDA) |
|
Chaeta development GO:0022416
The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
|
4 | M9NEW2 (/IMP) Q7YTZ9 (/IMP) Q9NHW0 (/IMP) Q9VM15 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | Q5TKR9 (/ISS) Q8BRB7 (/ISS) Q8BZ21 (/ISS) Q8WML3 (/ISS) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | M9NEW2 (/TAS) Q7YTZ9 (/TAS) Q9NHW0 (/TAS) Q9VM15 (/TAS) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | Q5TKR9 (/ISS) Q8BRB7 (/ISS) Q8BZ21 (/ISS) Q8WML3 (/ISS) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
4 | M9NEW2 (/IDA) Q7YTZ9 (/IDA) Q9NHW0 (/IDA) Q9VM15 (/IDA) |
|
Imaginal disc fusion, thorax closure GO:0046529
The joining of the parts of the wing imaginal discs, giving rise to the adult thorax.
|
4 | M9NEW2 (/IMP) Q7YTZ9 (/IMP) Q9NHW0 (/IMP) Q9VM15 (/IMP) |
|
Wing disc dorsal/ventral pattern formation GO:0048190
The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing.
|
4 | M9NEW2 (/IGI) Q7YTZ9 (/IGI) Q9NHW0 (/IGI) Q9VM15 (/IGI) |
|
Cartilage condensation GO:0001502
The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes.
|
3 | A2CG09 (/IMP) B3DK07 (/IMP) Q6J514 (/IMP) |
|
Embryonic pattern specification GO:0009880
The process that results in the patterns of cell differentiation that will arise in an embryo.
|
3 | A2CG09 (/IMP) B3DK07 (/IMP) Q6J514 (/IMP) |
|
Anterior/posterior pattern specification GO:0009952
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
3 | A2CG09 (/IGI) B3DK07 (/IGI) Q6J514 (/IGI) |
|
Embryonic body morphogenesis GO:0010172
The process in which the anatomical structures of the embryonic soma are generated and organized.
|
3 | A2CG09 (/IMP) B3DK07 (/IMP) Q6J514 (/IMP) |
|
Neural crest cell fate specification GO:0014036
The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
|
3 | A2CG09 (/IMP) B3DK07 (/IMP) Q6J514 (/IMP) |
|
Embryonic viscerocranium morphogenesis GO:0048703
The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.
|
3 | A2CG09 (/IGI) B3DK07 (/IGI) Q6J514 (/IGI) |
|
Embryonic viscerocranium morphogenesis GO:0048703
The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.
|
3 | A2CG09 (/IMP) B3DK07 (/IMP) Q6J514 (/IMP) |
|
Embryonic skeletal system development GO:0048706
The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure.
|
3 | A2CG09 (/IMP) B3DK07 (/IMP) Q6J514 (/IMP) |
|
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
|
3 | A2CG09 (/IGI) B3DK07 (/IGI) Q6J514 (/IGI) |
|
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
|
3 | A2CG09 (/IMP) B3DK07 (/IMP) Q6J514 (/IMP) |
|
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
|
2 | Q5SVQ0 (/ISS) Q810T5 (/ISS) |
|
Protein acetylation GO:0006473
The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic
|
2 | Q5TKR9 (/ISS) Q8BZ21 (/ISS) |
|
Internal peptidyl-lysine acetylation GO:0018393
The addition of an acetyl group to a non-terminal lysine residue in a protein.
|
2 | Q5SVQ0 (/ISS) Q810T5 (/ISS) |
|
Myeloid cell differentiation GO:0030099
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.
|
2 | Q5TKR9 (/ISS) Q8BZ21 (/ISS) |
|
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
|
2 | Q5SVQ0 (/ISO) Q8BZ21 (/ISO) |
|
Histone H4-K5 acetylation GO:0043981
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone.
|
2 | Q5SVQ0 (/ISS) Q810T5 (/ISS) |
|
Histone H4-K8 acetylation GO:0043982
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone.
|
2 | Q5SVQ0 (/ISS) Q810T5 (/ISS) |
|
Histone H4-K12 acetylation GO:0043983
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone.
|
2 | Q5SVQ0 (/ISS) Q810T5 (/ISS) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q8WYB5 (/IDA) Q92794 (/IDA) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | Q5SVQ0 (/ISO) Q8BRB7 (/ISO) |
|
Cellular senescence GO:0090398
A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.
|
2 | Q5TKR9 (/ISS) Q8BZ21 (/ISS) |
|
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
|
1 | Q7ZW29 (/IMP) |
|
Heart morphogenesis GO:0003007
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | Q8BZ21 (/IGI) |
|
Heart morphogenesis GO:0003007
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | Q8BZ21 (/IMP) |
|
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
|
1 | Q5SVQ0 (/ISO) |
|
DNA packaging GO:0006323
Any process in which DNA and associated proteins are formed into a compact, orderly structure.
|
1 | Q92794 (/TAS) |
|
Nucleosome assembly GO:0006334
The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
|
1 | Q8WYB5 (/NAS) |
|
Chromatin silencing GO:0006342
Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin.
|
1 | A0A1D8PS09 (/NAS) |
|
Chromatin silencing at telomere GO:0006348
Repression of transcription of telomeric DNA by altering the structure of chromatin.
|
1 | P34218 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q8WYB5 (/NAS) |
|
Protein acetylation GO:0006473
The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic
|
1 | Q92794 (/IDA) |
|
Protein acetylation GO:0006473
The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic
|
1 | Q8BZ21 (/ISO) |
|
Neuroblast proliferation GO:0007405
The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron.
|
1 | Q9W1A9 (/IMP) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | Q5TKR9 (/IDA) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | Q8BZ21 (/ISO) |
|
Mushroom body development GO:0016319
The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.
|
1 | Q9W1A9 (/IMP) |
|
Covalent chromatin modification GO:0016569
The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups.
|
1 | P34218 (/IMP) |
|
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
|
1 | Q8BZ21 (/ISO) |
|
Internal peptidyl-lysine acetylation GO:0018393
The addition of an acetyl group to a non-terminal lysine residue in a protein.
|
1 | Q5SVQ0 (/ISO) |
|
Myeloid cell differentiation GO:0030099
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.
|
1 | Q92794 (/IDA) |
|
Myeloid cell differentiation GO:0030099
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.
|
1 | Q8BZ21 (/ISO) |
|
Chromatin silencing at silent mating-type cassette GO:0030466
Repression of transcription at silent mating-type loci by alteration of the structure of chromatin.
|
1 | P34218 (/IMP) |
|
Stress-activated protein kinase signaling cascade GO:0031098
A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals.
|
1 | Q5SVQ0 (/ISO) |
|
Negative regulation of chromatin silencing at telomere GO:0031939
Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing at telomeres.
|
1 | Q10325 (/IMP) |
|
Dorsal/ventral axon guidance GO:0033563
The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
|
1 | Q9W1A9 (/IMP) |
|
Negative regulation of extent of heterochromatin assembly GO:0033696
Any process that reduces the extent of heterochromatin formation; reduces the size of a chromosomal region converted to heterochromatin.
|
1 | Q10325 (/IGI) |
|
Somatic stem cell population maintenance GO:0035019
Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.
|
1 | Q8BZ21 (/IMP) |
|
Embryonic hemopoiesis GO:0035162
The stages of blood cell formation that take place within the embryo.
|
1 | Q8BZ21 (/IMP) |
|
Aorta morphogenesis GO:0035909
The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.
|
1 | Q8BZ21 (/IGI) |
|
Aorta morphogenesis GO:0035909
The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.
|
1 | Q8BZ21 (/IMP) |
|
Female germ-line stem cell population maintenance GO:0036099
The process by which an organism or tissue maintains a population of female germ-line stem cells.
|
1 | Q9W1A9 (/IMP) |
|
Negative regulation of DNA-binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
|
1 | Q8BZ21 (/IMP) |
|
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
|
1 | Q8BZ21 (/IMP) |
|
Histone H4-K5 acetylation GO:0043981
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone.
|
1 | Q5SVQ0 (/ISO) |
|
Histone H4-K8 acetylation GO:0043982
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone.
|
1 | Q5SVQ0 (/ISO) |
|
Histone H4-K12 acetylation GO:0043983
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone.
|
1 | Q5SVQ0 (/ISO) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q8BZ21 (/ISO) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q8BZ21 (/ISO) |
|
Regulation of meiotic cell cycle GO:0051445
Any process that modulates the rate or extent of progression through the meiotic cell cycle.
|
1 | Q10325 (/IMP) |
|
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
|
1 | Q9W1A9 (/IDA) |
|
Face morphogenesis GO:0060325
The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.
|
1 | Q8BZ21 (/IGI) |
|
Face morphogenesis GO:0060325
The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.
|
1 | Q8BZ21 (/IMP) |
|
Response to sorbitol GO:0072708
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus.
|
1 | Q5SVQ0 (/ISO) |
|
Response to hydroxyurea GO:0072710
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.
|
1 | Q5SVQ0 (/ISO) |
|
Response to actinomycin D GO:0072716
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus.
|
1 | Q5SVQ0 (/ISO) |
|
Response to dithiothreitol GO:0072720
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus.
|
1 | Q5SVQ0 (/ISO) |
|
Response to anisomycin GO:0072739
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus.
|
1 | Q5SVQ0 (/ISO) |
|
Positive regulation of histone H4 acetylation GO:0090240
Any process that increases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.
|
1 | Q5SVQ0 (/ISO) |
|
Cellular senescence GO:0090398
A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.
|
1 | Q92794 (/IMP) |
|
Cellular senescence GO:0090398
A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.
|
1 | Q8BZ21 (/ISO) |
|
Positive regulation of protein localization to nucleus GO:1900182
Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
|
1 | Q5SVQ0 (/ISO) |
|
Regulation of signal transduction by p53 class mediator GO:1901796
Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.
|
1 | Q92794 (/TAS) |
|
Heterochromatin maintenance involved in chromatin silencing at centromere outer repeat region GO:1902368
Any heterochromatin maintenance that is involved in chromatin silencing at centromere outer repeat region.
|
1 | Q10325 (/IGI) |
|
Cellular response to leukemia inhibitory factor GO:1990830
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.
|
1 | Q8BRB7 (/IEP) |
|
Negative regulation of stem cell differentiation GO:2000737
Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.
|
1 | Q9W1A9 (/IGI) |
|
Negative regulation of stem cell differentiation GO:2000737
Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.
|
1 | Q9W1A9 (/IMP) |
There are 32 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
32 |
M9NEW2 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(22 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
30 |
E7EUP3 (/IDA)
E7EUP3 (/IDA)
E7EUP3 (/IDA)
E7EUP3 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(20 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
29 |
E7EUP3 (/IDA)
E7EUP3 (/IDA)
E7EUP3 (/IDA)
E7EUP3 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(19 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
27 |
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
O95251 (/TAS)
(17 more) |
|
Histone acetyltransferase complex GO:0000123
A protein complex that possesses histone acetyltransferase activity.
|
25 |
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
O95251 (/IDA)
(15 more) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
4 | A2CG09 (/IDA) B3DK07 (/IDA) Q10325 (/IDA) Q6J514 (/IDA) |
|
MOZ/MORF histone acetyltransferase complex GO:0070776
A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.
|
4 | Q5TKR9 (/ISS) Q8BRB7 (/ISS) Q8BZ21 (/ISS) Q8WML3 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | A2CG09 (/IC) B3DK07 (/IC) Q6J514 (/IC) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | Q5SVQ0 (/ISO) Q8BRB7 (/ISO) Q8BZ21 (/ISO) |
|
MOZ/MORF histone acetyltransferase complex GO:0070776
A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.
|
3 | Q8WYB5 (/IDA) Q92794 (/IDA) Q9W1A9 (/IDA) |
|
Histone acetyltransferase complex GO:0000123
A protein complex that possesses histone acetyltransferase activity.
|
2 | Q5SVQ0 (/ISS) Q810T5 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q5TKR9 (/ISS) Q8BZ21 (/ISS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | Q5SVQ0 (/ISS) Q810T5 (/ISS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q5SVQ0 (/ISO) Q8BZ21 (/ISO) |
|
PML body GO:0016605
A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.
|
2 | Q5TKR9 (/ISS) Q8BZ21 (/ISS) |
|
Histone acetyltransferase complex GO:0000123
A protein complex that possesses histone acetyltransferase activity.
|
1 | Q5SVQ0 (/ISO) |
|
Nucleosome GO:0000786
A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
|
1 | Q8WYB5 (/NAS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q10325 (/HDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q8WYB5 (/TAS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q5SVQ0 (/ISO) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q92794 (/IDA) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q8BZ21 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q10325 (/HDA) |
|
PML body GO:0016605
A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.
|
1 | Q92794 (/IDA) |
|
PML body GO:0016605
A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.
|
1 | Q8BZ21 (/ISO) |
|
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
1 | Q92794 (/IDA) |
|
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
1 | Q8BZ21 (/ISO) |
|
NuA3 histone acetyltransferase complex GO:0033100
A Gcn5-independent multisubunit complex that catalyzes the acetylation of histone H3. The budding yeast complex includes Sas3p, Taf30p, and Yng1p.
|
1 | P34218 (/IDA) |
|
Mst2 histone acetyltransferase complex GO:0036410
A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3, and contains Mst2 as the catalytic subunit. In fission yeast, contains at least Mst2, Nto1, Ptf2, Ptf1 and Eaf6.
|
1 | Q10325 (/TAS) |
|
MOZ/MORF histone acetyltransferase complex GO:0070776
A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.
|
1 | Q8BZ21 (/ISO) |
|
NuA3a histone acetyltransferase complex GO:1990467
A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Yng1p and associates with H3K4me3 using Yng1p.
|
1 | P34218 (/IDA) |
|
NuA3b histone acetyltransferase complex GO:1990468
A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Pdp3 and associates with H3K4me3 via Pdp3p.
|
1 | P34218 (/IDA) |