The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
1134
3D
2rc4A02 - 88.4
2
1043
3D
2ou2A02 - 87.9
3
800 - - 83.2
4
604
3D
4nsqD00 - 80.7
7
1
438
3D
4r9mC00 - 69.3
5
376 - - 95.4
6
348 - - 95.5
8
291 - - 39.0
9
256 - - 63.4
11
253
3D
3bj8D00 - 94.7
10
253 - - 80.2
12
210 - - 38.0
13
208 - - 86.6
14
205
3D
6c9mD00 - 65.9
15
201 - - 76.5
18
195
3D
2cntD00 - 78.9
16
192 - - 95.0
17
191 - - 77.8
19
181 - - 65.7
26
179
3D
3dr8B00 - 93.8
20
178
3D
4h6zB02 - 78.7
21
175
3D
1l0cA00 - 79.9
22
165
3D
2p0wB02 - 77.3
25
156
3D
2vqyA00 - 43.7
23
153 - - 78.4
24
149 - - 52.5
29
147
3D
4ab7H02 - 98.0
28
141
3D
5icwB00 - 68.5
27
140 - - 8.4
31
129
3D
3cxsA01 - 74.7
30
123 - - 80.7
42
116
3D
2p6gF01 - 78.7
32
115 - - 26.7
33
113 - - 86.4
34
112 - - 77.3
35
110
3D
1xebH00 - 85.8
56
100
3D
2p6gF02 - 89.3
36
96 - - 11.1
46
89
3D
3v8iB00 - 97.1
38
87
3D
5ls7B00 - 10.1
37
85 - - 76.8
39
78 - - 80.3
43
78
3D
4ag9B01 - 92.9
40
putative
77 - - 78.9
41
76 - - 84.1
44
76
3D
2ft0B00 - 53.0
45
74
3D
4k30Y00 - 78.4
52
69
3D
1z9uB00 - 33.9
47
69
3D
3tcvB00 - 94.0
48
68
3D
3t90A00 - 93.3
49
65 - - 85.3
60
64
3D
4u9zA00 - 86.4
50
64 - - 8.9
51
63 - - 75.7
55
61
3D
1y9wB01 - 77.1
54
Met
61
3D
2zpaB03 - 69.3
53
60 - - 73.4
62
60
3D
3fxtH00 - 92.3
57
57 - - 42.5
58
Nat5
55 - - 74.4
59
54 - - 78.0
61
N
alpha
53 - - 70.2
66
53
3D
1qsoD00 - 89.8
64
51
3D
2fe7B00 - 93.7
63
50 - - 57.6
112
49
3D
6b3tA01 - 94.7
65
48 - - 89.0
71
43
3D
4f0yB00 - 80.6
68
43 - - 23.4
67
43 - - 81.6
70
42
3D
3s6kA02 - 80.5
69
41 - - 13.9
78
38
3D
2pswC00 - 16.9
72
35 - - 92.7
74
N
alpha
34 - - 24.0
73
34 - - 74.4
75
33 - - 73.4
76
33 - - 89.9
77
32 - - 89.0
80
31 - - 70.7
82
31 - - 67.5
81
31 - - 36.2
79
31 - - 38.4
98
30
3D
4kvoH00 - 53.0
136
29
3D
1i21Y00 - 82.8
89
29
3D
2c27A00 - 45.8
83
NAT
29 - - 68.0
84
28 - - 65.9
85
27 - - 62.4
86
27 - - 84.0
87
27 - - 5.2
90
26 - - 24.6
106
26
3D
2q4yA00 - 97.1
88
26 - - 71.7
91
25 - - 86.3
107
25
3D
4xpdB00 - 52.1
92
24 - - 59.4
105
24
3D
3i3gB00 - 93.8
94
24 - - 74.0
93
24 - - 29.4
96
23 - - 18.4
95
23 - - 79.8
114
22
3D
4psxD02 - 86.4
97
22 - - 75.1
99
21 - - 73.7
100
21 - - 95.0
101
20 - - 57.3
149
AAC(2'
20
3D
1m4iB00 - 9.1
111
6'
20
3D
1s3zB00 - 1.5
148
20
3D
1yk3H00 - 0.0
102
20 - - 6.3
104
20 - - 80.2
103
20 - - 38.7
108
19 - - 76.7
109
19 - - 10.8
110
19 - - 17.4
176
19
3D
2vzzD00 - 0.0
116
18 - - 75.8
113
18 - - 65.9
115
18 - - 10.7
133
18
3D
1mk4B00 - 93.6
117
17 - - 71.0
124
17 - - 72.0
120
N
alpha
17 - - 0.0
183
17
3D
5ib0G00 - 0.0
121
17 - - 9.2
119
17 - - 17.2
122
GNAT
17 - - 1.4
118
17 - - 72.7
123
17 - - 2.4
127
16 - - 12.0
128
16 - - 88.8
132
16 - - 78.7
129
16 - - 2.6
131
16 - - 5.0
130
16 - - 14.2
125
16 - - 71.6
126
16 - - 8.2
135
15 - - 37.3
200
15
3D
5c88B00 - 83.5
194
15
3D
4avcB02 - 31.2
134
15 - - 2.4
137
14 - - 0.0
139
14 - - 54.6
203
14
3D
4y49O00 - 0.7
138
14 - - 54.2
140
Met
14 - - 83.1
142
13 - - 79.4
141
13 - - 56.1
144
13 - - 5.7
171
13
3D
2h5mA00 - 10.0
143
13 - - 12.7
153
12 - - 0.0
155
12 - - 0.8
154
12 - - 0.0
158
12 - - 98.1
147
12 - - 2.4
145
12 - - 16.7
152
12 - - 4.6
157
12 - - 11.7
146
12 - - 42.7
151
12 - - 0.7
156
12 - - 68.7
215
12
3D
4x5kA00 - 26.6
150
12 - - 25.5
180
11 - - 78.8
170
11 - - 8.1
175
11 - - 6.8
181
11 - - 92.3
165
11 - - 53.4
168
11 - - 84.7
178
11 - - 0.0
161
11 - - 33.1
174
11 - - 10.2
179
11 - - 36.9
164
11 - - 39.3
160
11 - - 0.0
177
11 - - 6.9
167
11 - - 80.1
163
11 - - 45.6
173
11 - - 0.0
159
11 - - 74.1
162
11 - - 45.9
169
11 - - 9.7
172
11 - - 8.3
166
11 - - 77.3
191
10 - - 98.7
187
10 - - 0.7
184
10 - - 11.0
192
10 - - 93.5
188
10 - - 0.0
189
10 - - 0.0
182
10 - - 82.6
186
10 - - 14.2
190
10 - - 0.0
185
10 - - 3.3
207
9 - - 0.8
198
NAT
9 - - 41.3
202
9 - - 14.0
209
9 - - 77.4
210
9 - - 41.5
199
9 - - 82.9
195
9 - - 33.8
204
9 - - 7.5
193
9 - - 42.3
205
9 - - 0.7
196
9 - - 19.9
206
9 - - 4.3
197
9 - - 1.9
208
9 - - 27.2
201
9 - - 7.5
212
8 - - 13.3
225
8 - - 45.2
222
8 - - 5.0
217
8 - - 13.2
213
8 - - 0.0
224
8 - - 0.0
211
8 - - 74.9
218
8 - - 0.0
221
8 - - 0.0
214
8 - - 67.9
219
8 - - 7.4
220
8 - - 0.0
223
8 - - 16.7
216
8 - - 73.1
246
7 - - 18.9
232
7 - - 44.6
229
7 - - 2.2
247
7 - - 2.6
242
7 - - 1.5
233
7 - - 34.1
243
7 - - 3.9
228
7 - - 5.6
238
7 - - 10.0
248
7 - - 82.5
236
7 - - 13.0
234
7 - - 84.5
227
7 - - 4.1
240
7 - - 0.0
230
Met
7 - - 0.0
239
7 - - 11.2
226
7 - - 43.4
244
7 - - 12.4
237
7 - - 18.2
235
7 - - 0.0
245
7 - - 6.5
241
7 - - 3.1
231
7 - - 48.6
272
6 - - 3.2
262
6 - - 0.0
278
6 - - 83.7
257
6 - - 61.7
281
NAT
6 - - 78.2
252
6 - - 23.5
271
6 - - 0.0
254
6 - - 0.0
279
6 - - 30.5
263
6 - - 0.0
267
6 - - 0.0
280
6 - - 85.8
273
6 - - 2.9
268
6 - - 0.0
253
6 - - 16.5
258
6 - - 3.9
260
6 - - 0.0
264
6 - - 14.4
255
6 - - 24.4
274
6 - - 1.6
250
6 - - 7.4
276
6 - - 0.0
259
6 - - 14.1
249
6 - - 20.6
621
6
3D
2g0bH01 - 0.0
269
6 - - 8.0
265
6 - - 0.0
275
6 - - 9.3
251
6 - - 6.8
256
6 - - 87.4
270
6 - - 8.3
266
6 - - 0.7
261
6 - - 14.9
282
6 - - 94.3
277
6 - - 0.0
285
5 - - 33.2
301
5 - - 0.0
294
5 - - 7.6
299
5 - - 7.8
305
N
alpha
5 - - 77.8
284
5 - - 23.2
289
5 - - 83.1
290
5 - - 52.4
293
5 - - 1.2
302
5 - - 36.1
298
5 - - 5.1
288
5 - - 74.0
287
N
alpha
5 - - 42.6
303
5 - - 36.4
297
5 - - 4.0
283
5 - - 78.4
379
1
5
3D
3k9uB00 - 0.0
295
5 - - 8.9
300
5 - - 0.0
286
5 - - 42.4
296
5 - - 0.0
292
5 - - 10.4
291
5 - - 16.5
304
5 - - 63.9
306
5 - - 84.2
340
NAT
4 - - 7.9
311
4 - - 18.5
308
4 - - 16.6
349
4 - - 18.7
323
4 - - 14.6
330
4 - - 0.0
307
4 - - 74.8
326
4 - - 12.6
335
4 - - 6.0
315
4 - - 69.6
317
4 - - 0.0
319
4 - - 9.8
344
4 - - 78.1
336
4 - - 0.0
342
4 - - 0.0
341
4 - - 9.0
309
4 - - 0.0
329
4 - - 4.4
346
N
alpha
4 - - 45.0
322
4 - - 0.0
310
4 - - 77.7
316
4 - - 16.3
314
4 - - 17.1
334
4 - - 3.3
339
4 - - 0.0
345
4 - - 11.0
318
4 - - 0.0
325
4 - - 15.1
337
4 - - 0.0
447
4
3D
2wpxB00 - 0.0
333
4 - - 18.5
347
4 - - 57.4
320
4 - - 5.5
338
4 - - 9.6
328
4 - - 12.7
313
4 - - 24.1
331
4 - - 8.2
348
4 - - 84.4
324
4 - - 10.4
312
Arylalkylamine N-AcetylTransferase
4 - - 18.0
332
4 - - 1.8
327
4 - - 0.0
343
4 - - 69.0
321
4 - - 0.0
350
3 - - 71.2
366
3 - - 0.0
359
3 - - 16.1
360
3 - - 69.2
353
3 - - 0.0
375
3 - - 9.0
387
3 - - 35.1
361
3 - - 6.7
383
3 - - 5.8
365
3 - - 14.1
382
3 - - 15.9
367
3 - - 5.3
351
3 - - 13.3
386
3 - - 12.2
372
3 - - 0.0
354
3 - - 0.0
355
3 - - 0.0
362
3 - - 4.4
376
3 - - 9.2
371
NAT
3 - - 7.8
356
3 - - 16.8
378
3 - - 0.0
381
3 - - 0.0
373
3 - - 9.3
385
3 - - 0.0
377
3 - - 1.5
363
3 - - 0.0
357
3 - - 1.6
358
3 - - 41.7
388
3 - - 57.3
364
3 - - 5.9
370
3 - - 0.6
380
3 - - 9.1
445
3
3D
2z0zA00 - 0.0
352
3 - - 59.9
369
3 - - 6.9
368
3 - - 5.7
374
3 - - 7.2
384
3 - - 0.0
512
2 - - 36.1
463
2 - - 0.0
458
2 - - 10.3
495
6
2 - - 0.0
486
2 - - 0.0
391
2 - - 65.7
444
2 - - 0.0
508
2 - - 26.9
506
Met
2 - - 0.0
456
2 - - 8.8
468
NAT
2 - - 7.6
413
2 - - 0.0
432
2 - - 0.0
477
2 - - 0.0
449
2 - - 0.0
501
2 - - 8.2
490
2 - - 0.0
461
2 - - 0.0
425
2 - - 6.7
395
2 - - 9.4
412
2 - - 2.8
440
2 - - 0.0
467
2 - - 4.2
481
2 - - 9.3
474
2 - - 0.0
472
2 - - 0.0
457
2 - - 0.0
505
2 - - 0.0
419
2 - - 31.0
406
2 - - 11.8
421
2 - - 31.7
491
6'
2 - - 0.0
408
O-GlcNAcase
2 - - 1.0
443
2 - - 0.0
431
2 - - 0.0
509
2 - - 35.7
453
2 - - 0.0
488
2 - - 0.0
405
2 - - 0.0
507
2 - - 0.0
392
2 - - 13.8
399
2 - - 7.5
436
NAT
2 - - 0.0
427
2 - - 0.0
426
2 - - 0.0
498
2 - - 4.8
483
2 - - 1.9
414
2 - - 0.0
462
2 - - 0.0
476
2 - - 8.2
469
2 - - 0.0
511
2 - - 44.2
471
2 - - 0.0
502
2 - - 0.0
423
2 - - 37.8
422
2 - - 39.1
402
2 - - 2.5
464
2 - - 0.0
439
2 - - 13.3
407
2 - - 0.0
435
2 - - 0.0
494
2 - - 9.9
487
2 - - 0.0
448
2 - - 0.0
396
2 - - 11.7
482
2 - - 0.0
499
AFU_orthologue AFUA_3G11780
2 - - 0.0
450
2 - - 0.9
473
2 - - 7.0
451
2 - - 0.0
454
2 - - 0.0
389
2 - - 33.9
410
2 - - 8.7
430
2 - - 3.4
415
2 - - 38.2
480
2 - - 1.4
438
2 - - 11.7
417
2 - - 24.1
493
2 - - 0.0
400
2 - - 4.4
475
2 - - 5.5
515
2 - - 43.9
446
2 - - 5.6
510
2 - - 36.2
393
2 - - 24.7
424
2 - - 40.7
434
2 - - 5.2
442
2 - - 0.0
465
2 - - 0.0
479
2 - - 11.7
503
2 - - 0.0
484
2 - - 0.0
397
2 - - 0.0
459
2 - - 0.0
401
2 - - 9.9
404
2 - - 4.6
516
2 - - 41.2
455
2 - - 0.0
470
2 - - 9.7
390
2 - - 0.0
437
2 - - 0.0
418
2 - - 21.3
485
2 - - 11.4
460
2 - - 0.0
452
2 - - 0.0
416
2 - - 19.8
496
6
2 - - 0.0
441
2 - - 0.0
428
2 - - 0.0
500
2 - - 0.0
394
2 - - 2.5
514
2 - - 42.0
513
2 - - 41.4
492
2 - - 0.0
429
2 - - 8.9
409
2 - - 0.0
489
2 - - 0.0
433
2 - - 0.0
497
2 - - 11.0
411
2 - - 0.0
478
2 - - 0.0
398
2 - - 3.0
504
2 - - 0.0
420
2 - - 31.6
403
2 - - 0.0
466
2 - - 8.8
517
1 - - 0.0
569
1 - - 0.0
686
NAT
1 - - 0.0
690
1 - - 0.0
536
1 - - 0.0
558
1 - - 0.0
573
1 - - 0.0
638
1 - - 0.0
661
1 - - 0.0
581
NAT
1 - - 0.0
678
1 - - 0.0
652
1 - - 0.0
606
1 - - 0.0
666
1 - - 0.0
545
1 - - 0.0
588
1 - - 0.0
542
1 - - 0.0
574
1 - - 0.0
660
1 - - 0.0
566
1 - - 0.0
526
1 - - 0.0
604
1 - - 0.0
659
1 - - 0.0
682
1 - - 0.0
626
1 - - 0.0
539
1 - - 0.0
520
1 - - 0.0
532
1 - - 0.0
584
1 - - 0.0
665
1 - - 0.0
649
1 - - 0.0
642
1 - - 0.0
648
1 - - 0.0
681
1 - - 0.0
554
1 - - 0.0
552
1 - - 0.0
563
1 - - 0.0
673
1 - - 0.0
546
1 - - 0.0
537
1 - - 0.0
529
1 - - 0.0
636
1 - - 0.0
600
1 - - 0.0
696
1 - - 0.0
670
1 - - 0.0
625
1 - - 0.0
570
1 - - 0.0
655
1 - - 0.0
597
1 - - 0.0
559
1 - - 0.0
580
1 - - 0.0
675
1 - - 0.0
662
1 - - 0.0
653
1 - - 0.0
685
1 - - 0.0
523
1 - - 0.0
595
1 - - 0.0
644
1 - - 0.0
568
1 - - 0.0
525
1 - - 0.0
691
1 - - 0.0
650
1 - - 0.0
629
1 - - 0.0
533
1 - - 0.0
615
1 - - 0.0
635
1 - - 0.0
575
1 - - 0.0
699
1 - - 0.0
543
1 - - 0.0
603
1 - - 0.0
565
1 - - 0.0
674
1 - - 0.0
553
1 - - 0.0
555
GNAT
1 - - 0.0
680
1 - - 0.0
679
1 - - 0.0
647
1 - - 0.0
593
1 - - 0.0
641
1 - - 0.0
616
1 - - 0.0
640
1 - - 0.0
562
1 - - 0.0
599
1 - - 0.0
609
1 - - 0.0
587
1 - - 0.0
624
1 - - 0.0
656
1 - - 0.0
596
1 - - 0.0
613
1 - - 0.0
547
1 - - 0.0
631
1 - - 0.0
528
1 - - 0.0
560
1 - - 0.0
634
1 - - 0.0
578
1 - - 0.0
695
1 - - 0.0
540
1 - - 0.0
684
1 - - 0.0
571
1 - - 0.0
594
1 - - 0.0
586
1 - - 0.0
534
1 - - 0.0
633
1 - - 0.0
519
1 - - 0.0
646
1 - - 0.0
556
1 - - 0.0
671
1 - - 0.0
692
1 - - 0.0
663
1 - - 0.0
658
1 - - 0.0
549
1 - - 0.0
614
1 - - 0.0
583
1 - - 0.0
591
1 - - 0.0
689
1 - - 0.0
619
1 - - 0.0
698
1 - - 0.0
524
1 - - 0.0
598
1 - - 0.0
602
1 - - 0.0
612
1 - - 0.0
564
1 - - 0.0
657
1 - - 0.0
576
1 - - 0.0
544
1 - - 0.0
623
1 - - 0.0
628
1 - - 0.0
630
1 - - 0.0
608
1 - - 0.0
522
1 - - 0.0
667
1 - - 0.0
561
1 - - 0.0
550
1 - - 0.0
592
1 - - 0.0
530
1 - - 0.0
654
1 - - 0.0
572
1 - - 0.0
527
1 - - 0.0
548
1 - - 0.0
627
1 - - 0.0
637
1 - - 0.0
579
1 - - 0.0
535
1 - - 0.0
683
NAT
1 - - 0.0
541
1 - - 0.0
567
GNAT
1 - - 0.0
605
1 - - 0.0
607
1 - - 0.0
694
1 - - 0.0
582
1 - - 0.0
557
1 - - 0.0
672
1 - - 0.0
677
1 - - 0.0
590
1 - - 0.0
664
1 - - 0.0
617
1 - - 0.0
651
1 - - 0.0
632
1 - - 0.0
610
1 - - 0.0
645
1 - - 0.0
589
1 - - 0.0
687
1 - - 0.0
620
1 - - 0.0
611
1 - - 0.0
585
1 - - 0.0
622
1 - - 0.0
538
1 - - 0.0
521
1 - - 0.0
668
1 - - 0.0
688
1 - - 0.0
693
1 - - 0.0
518
1 - - 0.0
601
1 - - 0.0
551
1 - - 0.0
697
1 - - 0.0
531
1 - - 0.0
669
1 - - 0.0
639
1 - - 0.0
577
1 - - 0.0
643
1 - - 0.0
676
1 - - 0.0
618
1 - - 0.0