The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Adenine phosphoribosyltransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 13 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Adenine phosphoribosyltransferase activity GO:0003999
Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.
154 O42842 (/IDA) P08030 (/IDA) P08030 (/IDA) P49435 (/IDA) P49435 (/IDA) P49435 (/IDA) P49435 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA)
(144 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
147 P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA)
(137 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
147 P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA)
(137 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
16 P63544 (/IPI) P63544 (/IPI) P63544 (/IPI) P63544 (/IPI) P63544 (/IPI) P63544 (/IPI) P63544 (/IPI) P63544 (/IPI) P63544 (/IPI) P63544 (/IPI)
(6 more)
Adenine phosphoribosyltransferase activity GO:0003999
Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.
8 Q9KT52 (/ISS) Q9KT52 (/ISS) Q9KT52 (/ISS) Q9KT52 (/ISS) Q9KT52 (/ISS) Q9KT52 (/ISS) Q9KT52 (/ISS) Q9KT52 (/ISS)
AMP binding GO:0016208
Interacting selectively and non-covalently with AMP, adenosine monophosphate.
4 P07741 (/IDA) P07741 (/IDA) P07741 (/IDA) P36972 (/IDA)
Adenine phosphoribosyltransferase activity GO:0003999
Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.
3 P07741 (/TAS) P07741 (/TAS) P07741 (/TAS)
Adenine binding GO:0002055
Interacting selectively and non-covalently with adenine, a purine base.
2 P08030 (/IDA) P08030 (/IDA)
Adenine phosphoribosyltransferase activity GO:0003999
Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.
2 P08030 (/IGI) P08030 (/IGI)
Adenine phosphoribosyltransferase activity GO:0003999
Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.
2 P08030 (/IMP) P08030 (/IMP)
Adenine phosphoribosyltransferase activity GO:0003999
Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.
2 Q5ARJ7 (/RCA) Q5ARJ7 (/RCA)
AMP binding GO:0016208
Interacting selectively and non-covalently with AMP, adenosine monophosphate.
2 P08030 (/ISO) P08030 (/ISO)
Transferase activity, transferring pentosyl groups GO:0016763
Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor).
1 O42842 (/IMP)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Adenine salvage GO:0006168
Any process that generates adenine, 6-aminopurine, from derivatives of it without de novo synthesis.
147 P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA)
(137 more)
Purine ribonucleoside salvage GO:0006166
Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis.
8 Q9KT52 (/ISS) Q9KT52 (/ISS) Q9KT52 (/ISS) Q9KT52 (/ISS) Q9KT52 (/ISS) Q9KT52 (/ISS) Q9KT52 (/ISS) Q9KT52 (/ISS)
Adenine salvage GO:0006168
Any process that generates adenine, 6-aminopurine, from derivatives of it without de novo synthesis.
6 P08030 (/IMP) P08030 (/IMP) P49435 (/IMP) P49435 (/IMP) P49435 (/IMP) P49435 (/IMP)
AMP biosynthetic process GO:0006167
The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate.
4 P49435 (/TAS) P49435 (/TAS) P49435 (/TAS) P49435 (/TAS)
Purine-containing compound salvage GO:0043101
Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis.
3 P07741 (/TAS) P07741 (/TAS) P07741 (/TAS)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
3 P07741 (/TAS) P07741 (/TAS) P07741 (/TAS)
Purine ribonucleoside salvage GO:0006166
Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis.
2 P08030 (/IGI) P08030 (/IGI)
Purine ribonucleoside salvage GO:0006166
Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis.
2 P08030 (/IMP) P08030 (/IMP)
Lactation GO:0007595
The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young.
2 P08030 (/ISO) P08030 (/ISO)
Grooming behavior GO:0007625
The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.
2 P08030 (/IGI) P08030 (/IGI)
Nucleotide salvage GO:0043173
Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis.
2 Q5ARJ7 (/RCA) Q5ARJ7 (/RCA)
Adenine metabolic process GO:0046083
The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
2 P08030 (/IC) P08030 (/IC)
Adenine metabolic process GO:0046083
The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
2 P08030 (/IGI) P08030 (/IGI)
Adenine metabolic process GO:0046083
The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
2 P08030 (/IMP) P08030 (/IMP)
Lactation GO:0007595
The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young.
1 P36972 (/IDA)
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
1 P36972 (/IEP)
AMP salvage GO:0044209
The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from derivatives of it (either adenine, ADP or adenosine 3',5'-bisphosphate) without de novo synthesis.
1 O42842 (/IDA)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
152 H3BQB1 (/IDA) H3BQF1 (/IDA) P07741 (/IDA) P07741 (/IDA) P07741 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA) P69503 (/IDA)
(142 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
148 O42842 (/HDA) P69503 (/HDA) P69503 (/HDA) P69503 (/HDA) P69503 (/HDA) P69503 (/HDA) P69503 (/HDA) P69503 (/HDA) P69503 (/HDA) P69503 (/HDA)
(138 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 O42842 (/HDA) P49435 (/HDA) P49435 (/HDA) P49435 (/HDA) P49435 (/HDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
5 H3BQB1 (/IDA) H3BQF1 (/IDA) P07741 (/IDA) P07741 (/IDA) P07741 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 P49435 (/HDA) P49435 (/HDA) P49435 (/HDA) P49435 (/HDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
3 P07741 (/TAS) P07741 (/TAS) P07741 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P07741 (/TAS) P07741 (/TAS) P07741 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 P07741 (/TAS) P07741 (/TAS) P07741 (/TAS)
Secretory granule lumen GO:0034774
The volume enclosed by the membrane of a secretory granule.
3 P07741 (/TAS) P07741 (/TAS) P07741 (/TAS)
Fungal biofilm matrix GO:0062040
An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses.
3 Q5ALX8 (/IDA) Q5ALX8 (/IDA) Q5ALX8 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
3 P07741 (/HDA) P07741 (/HDA) P07741 (/HDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 P08030 (/ISO) P08030 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P08030 (/ISO) P08030 (/ISO)