CATH Superfamily 3.40.50.2020

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	Ribose-phosphate pyrophosphokinase	2463	3D	4s2uA01	-	92.2
2	Ribose-phosphate pyrophosphokinase	2380	3D	4s2uA02	-	97.4
3	Uracil phosphoribosyltransferase	1474	3D	2ehjD00	-	97.5
4	Adenine phosphoribosyltransferase	1024	3D	5vjpB00	-	91.3
6	Hypoxanthine phosphoribosyltransferase	952	3D	1grvB00	-	95.9
5	Ribose-phosphate pyrophosphokinase 1	903	3D	4m0uB02	-	94.5
7	Ribose-phosphate pyrophosphokinase	736	3D	1u9zD01	-	94.6
8	Orotate phosphoribosyltransferase	639	3D	4wn3A00	-	89.3
9	Xanthine phosphoribosyltransferase	603	3D	1nulB00	-	67.4
10	Uridine-cytidine kinase	549		-	-	96.3
11	Putative ribose-phosphate pyrophosphokinase 1	540		-	-	85.1
12	Phosphoribosyl pyrophosphate synthase-associated protein 2 isoform 1	502		-	-	77.4
13	Amidophosphoribosyltransferase	478	3D	6czfD02	-	73.7
14	Ribose-phosphate pyrophosphokinase 1	379		-	-	93.2
15	Uridine kinase	356		-	-	76.2
19	Hypoxanthine phosphoribosyltransferase	336	3D	2vfaB00	-	79.4
16	Ribose-phosphate pyrophosphokinase II	305		-	-	75.5
20	Bifunctional protein PyrR	302	3D	1w30B00	-	85.1
17	Ribose-phosphate pyrophosphokinase 1	283		-	-	80.1
18	Phosphoribosyl pyrophosphate synthase-associated protein 2	275		-	-	72.4
21	Adenine phosphoribosyltransferase	238	3D	4m0kD00	-	94.1
23	Probable uracil phosphoribosyltransferase	223	3D	1upuD00	-	92.9
22	Adenine phosphoribosyltransferase 1	212		-	-	73.0
24	Putative phosphoribosyl pyrophosphate synthase-associated protein 1	204	3D	2c4kF01	-	80.2
25	Uridine monophosphate synthetase	187	3D	2wnsB00	-	93.9
26	Uracil phosphoribosyltransferase homolog	182		-	-	76.7
27	Xanthine phosphoribosyltransferase	176	3D	2fxvB00	-	53.4
29	Orotate phosphoribosyltransferase	146	3D	5hklB00	-	92.4
28	Amidophosphoribosyltransferase	144		-	-	80.9
30	Ribose-phosphate pyrophosphokinase II	124		-	-	74.6
31	Probable PRS4-ribose-phosphate pyrophosphokinase 3	109		-	-	93.1
32	ribose-phosphate pyrophosphokinase 4	101		-	-	71.4
33	Xanthine phosphoribosyltransferase 1	94	3D	2xbuB00	-	80.0
35	Hypoxanthine phosphoribosyltransferase	90	3D	4qyiE00	-	18.8
34	Ribose-phosphate pyrophosphokinase 4	85		-	-	71.0
36	Uncharacterized protein, isoform B	76		-	-	70.3
46	Hypoxanthine-guanine phosphoribosyltransferase	68	3D	6apvD00	-	83.9
37	Phosphoribosylpyrophosphate synthetase	64		-	-	71.0
38	Hypoxanthine phosphoribosyltransferase	64	3D	2jbhB00	-	76.6
39	Ribose-phosphate pyrophosphokinase	61		-	-	24.4
40	Phosphoribosyl pyrophosphate synthetase 1	53		-	-	53.3
41	Hypoxanthine-guanine phosphoribosyltransferase	51		-	-	83.2
64	Hypoxanthine phosphoribosyltransferase	51	3D	3ozgD00	-	54.7
42	Putative ribose-phosphate pyrophosphokinase	50		-	-	13.7
43	Ribose-phosphate pyrophosphokinase 1	49		-	-	91.2
44	Pur operon repressor	47		-	-	7.6
45	Phosphoribosyl pyrophosphate synthetase 2	38		-	-	7.3
47	Ribose-phosphate pyrophosphokinase II	31		-	-	49.4
48	Hypoxanthine phosphoribosyltransferase	30		-	-	14.4
49	Putative uracil phosphoribosyltransferase urg2	28		-	-	83.8
74	Ribose-phosphate pyrophosphokinase	27	3D	4twbF02	-	92.4
123	Adenine phosphoribosyltransferase	27	3D	6fd6B00	-	46.2
53	Hypoxanthine phosphoribosyltransferase	26	3D	5ipfD00	-	85.2
52	Orotate phosphoribosyltransferase	23		-	-	42.7
50	Related to XPT1-xanthine phosphoribosyl transferase	23		-	-	65.7
51	Ribose-phosphate pyrophosphokinase 1	23		-	-	70.2
55	Ribose-phosphate pyrophosphokinase	20		-	-	31.9
56	Ribose-phosphate pyrophosphokinase II	20		-	-	72.9
54	ComF family protein	20		-	-	47.7
58	Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase	20	3D	3qw4C02	-	89.8
57	Hypoxanthine phosphoribosyltransferase	19		-	-	76.5
61	PRS5p 5-phospho-ribosyl-1 Alpha	17		-	-	23.8
83	Ribose-phosphate pyrophosphokinase	17	3D	4twbF01	-	77.6
59	Orotate phosphoribosyltransferase	17		-	-	8.9
60	Ribose-phosphate pyrophosphokinase, putative	17		-	-	14.2
63	Phosphoribosylpyrophosphate synthetase	16		-	-	32.0
62	Ribose-phosphate pyrophosphokinase, putative	16		-	-	3.3
68	Predicted protein	15		-	-	72.7
65	Ribose-phosphate pyrophosphokinase putative	15		-	-	75.7
67	Ribose-phosphate diphosphokinase	15		-	-	33.0
66	Ribose-phosphate pyrophosphokinase 2	15		-	-	5.3
71	ribose-phosphate pyrophosphokinase 2	14		-	-	6.1
70	Ribose-phosphate pyrophosphokinase, putative	14		-	-	18.7
69	Zgc:174895	14		-	-	73.4
73	Uncharacterized protein, isoform L	13		-	-	2.1
72	Uncharacterized protein, isoform I	13		-	-	1.1
76	Phosphoribosylpyrophosphate synthetase	12		-	-	46.7
75	Adenine phosphoribosyltransferase	12		-	-	18.8
92	Adenine phosphoribosyltransferase	12	3D	1qcdA00	-	39.4
81	Putative ribose-phosphate pyrophosphokinase	11		-	-	9.0
78	ribose-phosphate pyrophosphokinase 4	11		-	-	96.8
82	Phosphoribosylpyrophosphate synthetase	11		-	-	3.5
79	Ribose-phosphate pyrophosphokinase, putative	11		-	-	21.1
80	Ribose-phosphate pyrophosphokinase	11		-	-	4.4
77	Phosphoribosyl pyrophosphate synthetase 2	11		-	-	39.9
84	Adenine phosphoribosyltransferase	10		-	-	23.7
87	Ribose-phosphate pyrophosphokinase, putative	10		-	-	42.3
85	Related to ribose-phosphate pyrophosphokinase II	10		-	-	54.8
86	Erythromycin esterase	10		-	-	9.3
88	Orotate phosphoribosyltransferase	9		-	-	8.4
90	Protein CBG07940	9		-	-	65.8
89	Adenine phosphoribosyltransferase 2	9		-	-	1.3
94	Phosphoribosyl transferase	8		-	-	0.0
91	Orotate phosphoribosyltransferase	8		-	-	29.3
93	Ribose-phosphate pyrophosphokinase, putative	8		-	-	11.4
107	Guanine phosphoribosyltransferase	8	3D	1dqpB00	-	4.6
99	Adenine phosphoribosyltransferase	8	3D	1l1rA00	-	13.3
98	Probable PRS4-ribose-phosphate pyrophosphokinase 3	7		-	-	13.0
96	Ribose-phosphate pyrophosphokinase	7		-	-	5.7
95	Ribose-phosphate pyrophosphokinase, putative	7		-	-	2.3
97	phosphoribosyl pyrophosphate synthase-associated protein 2 isoform X4	7		-	-	5.1
101	Ribose-phosphate pyrophosphokinase, putative	6		-	-	47.0
100	Ribose-phosphate pyrophosphokinase, putative	6		-	-	0.8
105	Uncharacterized protein	5		-	-	14.3
106	Uridine kinase, putative AFU_orthologue AFUA_2G05430	5		-	-	92.2
102	Hypoxanthine phosphoribosyltransferase	5		-	-	1.9
104	Ribose-phosphate pyrophosphokinase 2 isoform x1	5		-	-	14.4
103	Ribose-phosphate pyrophosphokinase	5		-	-	2.9
109	Orotate phosphoribosyltransferase	4		-	-	14.8
112	Uncharacterized protein	4		-	-	24.5
110	ribose-phosphate pyrophosphokinase 4	4		-	-	65.4
108	Phosphoribosyl transferase domain protein	4		-	-	4.5
111	Ribose-phosphate pyrophosphokinase	4		-	-	15.1
113	Probable adenine phosphoribosyltransferase	3		-	-	48.9
121	Uridine kinase	3		-	-	0.0
114	Orotate phosphoribosyltransferase	3		-	-	0.0
116	Phosphoribosyl pyrophosphate synthetase-associated protein 1	3		-	-	12.0
117	Phosphoribosyl pyrophosphate synthetase	3		-	-	0.8
118	Adenine phosphoribosyltransferase	3		-	-	5.1
122	Uridine cytidine kinase I, putative	3		-	-	64.7
124	Uridine cytidine kinase I, putative	3		-	-	57.7
120	Uridine kinase	3		-	-	0.0
115	Hypoxanthine-guanine phosphoribosyltransferase	3		-	-	5.3
119	Phosphoribosyl pyrophosphate synthetase	3		-	-	1.5
133	Adenine phosphoribosyltransferase 1, chloroplastic	2		-	-	0.0
146	Uncharacterized protein	2		-	-	26.4
128	Uracil phosphoribosyltransferase-domain-containing protein	2		-	-	0.0
127	Orotate phosphoribosyltransferase	2		-	-	0.0
140	Uncharacterized protein	2		-	-	10.1
134	Adenine phosphoribosyltransferase, putative	2		-	-	0.0
132	Adenine phosphoribosyltransferase 4	2		-	-	0.0
130	Uncharacterized protein	2		-	-	8.4
136	Ribose-phosphate pyrophosphokinase	2		-	-	0.0
142	Uncharacterized protein	2		-	-	0.0
144	Uncharacterized protein	2		-	-	0.0
143	Uncharacterized protein	2		-	-	0.0
125	Hypoxanthine phosphoribosyltransferase	2		-	-	13.7
129	Hypoxanthine phosphoribosyltransferase	2		-	-	7.9
145	Uncharacterized protein	2		-	-	36.8
131	Hypoxanthine phosphoribosyltransferase	2		-	-	8.0
137	Ribose-phosphate pyrophosphokinase	2		-	-	0.0
138	Phosphoribosyl pyrophosphate synthase-associated protein 2	2		-	-	0.0
126	Uncharacterized protein	2		-	-	0.0
135	Uncharacterized protein	2		-	-	20.3
141	Ribose-phosphate pyrophosphokinase 1, putative	2		-	-	0.0
139	Ribose-phosphate pyrophosphokinase	2		-	-	0.0
151	Upp protein	1		-	-	0.0
177	Predicted protein	1		-	-	0.0
178	Uncharacterized protein	1		-	-	0.0
180	Uncharacterized protein	1		-	-	0.0
171	Uncharacterized protein	1		-	-	0.0
158	Uncharacterized protein	1		-	-	0.0
186	Orotate phosphoribosyltransferase	1		-	-	0.0
157	Uncharacterized protein	1		-	-	0.0
165	Uncharacterized protein	1		-	-	0.0
169	Ribose-phosphate pyrophosphokinase	1		-	-	0.0
161	Hypoxanthine-guanine phosphoribosyltransferase, putative	1		-	-	0.0
175	Phosphoribosyl transferase domain containing protein	1		-	-	0.0
184	Ribose phosphate diphosphokinase Prs1, putative AFU_orthologue AFUA_7G05670	1		-	-	0.0
179	Uncharacterized protein	1		-	-	0.0
182	Ribose-phosphate pyrophosphokinase 2 chloroplastic	1		-	-	0.0
168	Uncharacterized protein	1		-	-	0.0
183	Ribose-phosphate pyrophosphokinase 2 chloroplastic	1		-	-	0.0
155	Putative competence protein F	1		-	-	0.0
167	Ribose phosphate pyrophosphokinase NadR	1		-	-	0.0
159	Uncharacterized protein	1		-	-	0.0
166	Ribose-phosphate pyrophosphokinase	1		-	-	0.0
153	Uncharacterized protein	1		-	-	0.0
185	Ribose-phosphate pyrophosphokinase 2 chloroplastic	1		-	-	0.0
160	Uncharacterized protein	1		-	-	0.0
189	Os02g0517564 protein	1		-	-	0.0
172	Uncharacterized protein	1		-	-	0.0
174	Uncharacterized protein	1		-	-	0.0
149	Hypoxanthine-guanine phosphoribosyltransferase	1		-	-	0.0
173	Uncharacterized protein	1		-	-	0.0
190	Uridine monophosphate synthetase	1		-	-	0.0
152	Probable adenine phosphoribosyltransferase	1		-	-	0.0
154	Hypoxanthine phosphoribosyltransferase	1		-	-	0.0
188	Dynein heavy chain 9	1		-	-	0.0
156	Uncharacterized protein	1		-	-	0.0
163	Ribose phosphate pyrophosphokinase NadR	1		-	-	0.0
187	Uncharacterized protein	1		-	-	0.0
150	Uncharacterized protein	1		-	-	0.0
147	Hypoxanthine/guanine phosphoribosyltransferase	1		-	-	0.0
148	Adenine phosphoribosyltransferase	1		-	-	0.0
176	Uncharacterized protein	1		-	-	0.0
181	AER083Cp	1		-	-	0.0
170	Uncharacterized protein	1		-	-	0.0
162	Ribose-phosphat pyrophosphokinase	1		-	-	0.0
164	Ribose-phosphate pyrophosphokinase	1		-	-	0.0

Network disruptions

Functional Families

Browse Functional Families